Puma concolor (puma): 112869526
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Entry
112869526 CDS
T08890
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
pcoo
Puma concolor (puma)
Pathway
pcoo04120
Ubiquitin mediated proteolysis
pcoo04144
Endocytosis
pcoo04330
Notch signaling pathway
pcoo04668
TNF signaling pathway
pcoo04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
pcoo00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
112869526 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
112869526 (ITCH)
04668 TNF signaling pathway
112869526 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
112869526 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
112869526 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pcoo04131
]
112869526 (ITCH)
04121 Ubiquitin system [BR:
pcoo04121
]
112869526 (ITCH)
Enzymes [BR:
pcoo01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
112869526 (ITCH)
Membrane trafficking [BR:
pcoo04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
112869526 (ITCH)
Ubiquitin system [BR:
pcoo04121
]
Ubiquitin ligases (E3)
HECT type E3
112869526 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
112869526
NCBI-ProteinID:
XP_025788454
UniProt:
A0A6P6IKX4
LinkDB
All DBs
Position
Unknown
AA seq
707 aa
AA seq
DB search
MSGSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVLTVEEVVVTLQLIGDKEPTETMGDLSVCLDGLQLESEVVTNGETTCSES
ASQNDDGSRPKDEASWEQRVDQHGRVYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYY
VDHFTRTTTWQRPTLESVRNYEQWQLQRSQLQGAMQQFNQRFIYGNQDLFTTSQNKEFDP
LGPLPPGWEKRTDSNGRVYFVNHNTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYF
VDHNRRTTTYIDPRTGKSALDNGPQIAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKT
LFEDSFQQIMSFNPQDLRRRLWVIFPGEEGLDYGGVARERFFVLSHEVLNPMYCLFEYAG
KDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKD
LESIDPEFYNSLIWVKENNIEERGLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEE
YIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRH
AIYRHYTRTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCI
EKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE
NT seq
2124 nt
NT seq
+upstream
nt +downstream
nt
atgtctggcagtggatcacagctgggttcaatgggtagcctgaccatgaaatcacagctt
cagatcactgtcatttcagcaaaacttaaagaaaataaaaagaattggtttggaccaagt
ccttatgtggaagtcacagttgatggacagtcaaagaagacagaaaaatgcaacaatacg
aacagtcccaaatggaagcaaccccttacagttcttacagttgaggaagtagttgtgact
ttacagcttataggtgacaaagagccaacagagacaatgggagacttgtcagtttgtctt
gatgggctgcagttagagtctgaagttgttactaatggtgaaactacatgttcagaaagt
gcttcacagaatgatgatggctctagaccgaaggatgaagcaagttgggagcagagagtg
gaccagcatgggcgagtttactacgtagatcatattgaaaaaagaacaacgtgggataga
ccagaacctctacctcctggctgggaacggcgggttgacaacatgggacgtatttattat
gttgaccatttcacaagaacaacaacgtggcagaggccgacattggaatctgtccggaac
tatgaacagtggcaactccaacgtagtcagcttcaaggagcaatgcagcaatttaaccag
agattcatttatgggaatcaggatttgtttactacatcgcaaaataaagaatttgatccc
cttggtcccctgcctcctggatgggagaagagaacagacagcaatggtagagtatatttt
gtcaaccacaacactcgtattacacaatgggaggaccccagaagtcaaggtcaattaaat
gaaaagcccttacctgaaggctgggaaatgagattcacagtagatggaattccatatttt
gtggaccacaatagaagaacaaccacctatattgatccccgcactggaaaatctgctcta
gacaatggaccacagatagcctacgtacgggacttcaaggcaaaggttcagtatttccgg
ttctggtgtcagcaactggcaatgccacagcacataaagattacagtgacaagaaaaaca
ttgtttgaagattcctttcagcagataatgagcttcaatccccaagatctgcgaagacgt
ttgtgggtgatttttccaggagaagaaggtttagattatggaggtgtagcaagagagagg
ttctttgttttgtcacacgaggtgttgaaccccatgtattgcctgtttgaatatgcagga
aaggataactactgcctgcagattaatcctgcttcttacatcaatccagatcacctgaaa
tattttcgttttattggcaggtttattgccatggctttgttccatgggaaattcatagac
acaggtttttctttgccattctataagcgtatattgaacaaaccagttggactcaaggat
ttagaatctattgatccagaattttacaattctctcatctgggttaaagaaaacaatatt
gaggaacgtggtttggaaatgtacttctctgtcgataaagaaattttaggtgaaatcaag
agtcatgatttgaaacctaatggtggcaatattcttgtgacagaagaaaataaagaggaa
tatatcagaatggtagctgaatggaggttgtctcgaggtgttgaagaacagacacaagct
ttctttgagggctttaatgaaattcttccccagcagtatttgcaatactttgatgcaaag
gaattagaggtccttttatgtggaatgcaagagattgatttgaatgactggcaaagacat
gccatctaccgtcattacactaggacaagcaaacaaatcatgtggttttggcagtttgtt
aaagaaattgataatgagaagagaatgagacttctgcagtttgttactggaacttgtcga
ttgccagttggaggatttgctgacctcatggggagcaatggaccacagaaattctgcatt
gaaaaagttgggaaagaaaactggttacccagaagtcatacctgttttaaccgcctggac
ctgccaccctacaagagctatgagcaactgaaggaaaagctgttatttgccattgaagaa
acagaaggatttggacaagagtaa
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