Puma concolor (puma): 112870451 Help Entry 112870451         CDS       T08890                                  Symbol ACACB Name (RefSeq) acetyl-CoA carboxylase 2   KO K01946   acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15] Organism pcoo  Puma concolor (puma) Pathway pcoo00061   Fatty acid biosynthesis pcoo00620   Pyruvate metabolism pcoo00640   Propanoate metabolism pcoo01100   Metabolic pathways pcoo04152   AMPK signaling pathway pcoo04910   Insulin signaling pathway pcoo04920   Adipocytokine signaling pathway pcoo04922   Glucagon signaling pathway pcoo04931   Insulin resistance pcoo04936   Alcoholic liver disease Brite KEGG Orthology (KO) [BR:pcoo00001]  09100 Metabolism   09101 Carbohydrate metabolism    00620 Pyruvate metabolism     112870451 (ACACB)    00640 Propanoate metabolism     112870451 (ACACB)   09103 Lipid metabolism    00061 Fatty acid biosynthesis     112870451 (ACACB)   09110 Biosynthesis of other secondary metabolites    00254 Aflatoxin biosynthesis     112870451 (ACACB)  09130 Environmental Information Processing   09132 Signal transduction    04152 AMPK signaling pathway     112870451 (ACACB)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     112870451 (ACACB)    04922 Glucagon signaling pathway     112870451 (ACACB)    04920 Adipocytokine signaling pathway     112870451 (ACACB)  09160 Human Diseases   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     112870451 (ACACB)    04931 Insulin resistance     112870451 (ACACB) Enzymes [BR:pcoo01000]  2. Transferases   2.1  Transferring one-carbon groups    2.1.3  Carboxy- and carbamoyltransferases     2.1.3.15  acetyl-CoA carboxytransferase      112870451 (ACACB)  6. Ligases   6.3  Forming carbon-nitrogen bonds    6.3.4  Other carbon-nitrogen ligases     6.3.4.14  biotin carboxylase      112870451 (ACACB)   6.4  Forming carbon-carbon bonds    6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)     6.4.1.2  acetyl-CoA carboxylase      112870451 (ACACB) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  ACC_central Carboxyl_trans CPSase_L_D2 ACCA_BT Biotin_carb_C Biotin_carb_N ATP-grasp Biotin_lipoyl Dala_Dala_lig_C ATP-grasp_3 Motif Other DBs NCBI-GeneID:  112870451 NCBI-ProteinID:  XP_025789381 UniProt:  A0A6P6IMA8 LinkDB All DBs Position Unknown AA seq 2169 aa AA seqDB search MTLLLFLSCLIFSCLTFSWLKFWGEMTDSKQVTKSTPEGSCSPSQAPFPASDSSGEPPQK DDNNGPLPETPNRAEPASHRGADDTDQQRTSGPPPHQNPPGDSLSSDDTSPAPQANATGT ADLKTPDTDGPSSPAKPQDPRARPLSKKDEKQEHIKRQLMTNFILGSFDDNSSDEDPSAG LFRESPRKGSRASLGTLSLEAALTAGEPENPVPTIRPSMSGLHLVKKGRELKKVDLHRDF TVASPAEFVTRFGGDRVIEKSGAFNLQDAEAAKGASSEHRVLVTLSVAVRSPAVTFSVSV FLSFPHLIAEYIKMADQYVPVPGGPNNNNYANVELVVDIAKRIPVQAVWAGWGHASENPK LPELLCKHEIAFLGPPSEAMWALGDKIASTIVAQTLQVPTLPWSGSGLMIEWAEDNLQEG KRISVPEDIYDQGCVKDVDEGLEVAEKIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQ VQSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIA TPAVFEFMEQCAVRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVN LPAAQLQGFKPSSGTVQELNFRSNKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEA ISNMVVALKELSIRGDFRTTVEYLINLLETERFQNNDIDTGWLDHLIAEKVQAEKPDIML GVVCGALNVADVMFRTCMTDFLHSLERGQVLPAASLLNIVDVELIYDGVKYIVKVARQSL TTFVLIMNGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRVTIGNKTCVFEKEND PTVLRSPSAGKLIQYTVEDGGHVEAGSSYAEMEVSTEPAPGVRLQPGLPSPHSPREDHPP SSSLHLSPGLPPADLLREPVCGVRPKFSPAEPFTGELPSQQTLPIIGEKLHQVFHNVLEN LTNVMNGYCLPEPIFSTKLKEWVQKLMTTLRHPSLPLLELQEIMTSVSGRIPAPVEKSVR RVMAQYASNITSVLCQFPSQQIATILDCHAATLQRKADREVFFMNTQSIVQLVQRYRSGT RGYMKAVVLDLLRRYLRVEHHFQQAHYDKCVINLREQLKPNMSQVLDCIFSHAQVAKKNQ LVIMLIDELCGPDPSLSEELTSILNELTQLSKSEHCKVALRARQILIASHLPSYELRHNQ VESIFLSAIDMYGHQFCPENLKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYI AYELNSLQHRQLPDGTCVVEFQFMLPSSHPNRYGKNILVEYGLRRITFLIAQEKEFPKFF TFRARDEFAEDRIYRHLEPALAFQLELSRMRSFDLTAVPCANHKMHLYLGAAKVKEGAEV TDHRFFIRAIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLN FVPTVIMDPFKIEESVRSMVMRYGSRLWKLRVLQAEVKINIRETTTGSAVPIRLFITNES GYYLDISLYKEVTDPRSGNIMFHSFGNKQGPQHGMLINTPYVTKDLLQAKRFQAQSLGTT YVYDFPEMFRQALLKLWGSTDDYPKDILTYTELVLDPQGQLVEMNRLPGGNEVGMVAFKM RFKTREYPEGRDAIVISNDITFRIGSFGLGEDLLYLRASEMARAEGIPKIYLAANSGACI GLAEEIKHMFQVAWVDPGDPHKGFKYLYLTPQDYTRISSLNSVRCKHIEEEGESRYVITD IIGKDRGLGVENLKGSGMIAGESSLAYEEIVTISMVTCRALGIGAYLVRLGQRVIQVENS HIILTGASALNKVLGREVYTSNNQLGGVQIMHHNGVSHVTVPDDFEGVYTILEWLSYMPK DNRSPVPITTPSDPIDREIGFFPSRAPYDPRWLLAGRPHPTLKGSWQSGFFDHGSFKEIM APWAQTVVTGRARLGGIPVGVIAVETRTVEVVVPADPANLDSEAKIIQQAGQVWFPDSAY KTAQAINDFNREGLPLIIFANWRGFSGGMKDMYDQVLKFGAYIVDSLRQYKQPVLIYIPP HGELRGGSWVVVDSSINPLCIETYADKESRASILEPEGTVEIKFRKKDLIKTMRRIDPVY KKLVEQLGVSELSDKDRRDLEGQLKAREDLLLPVYHQVAVLFADLHDRAHGMLEKGVVSV RACSCGSPT NT seq 6510 nt NT seq  +upstreamnt  +downstreamnt atgaccttgcttctttttctatcttgtttgattttctcctgcttgaccttctcctggtta aaattctggggggaaatgacagactccaagcaagtcaccaagagcacacccgaagggagc tgtagcccaagccaagcgccttttccagcctcagacagctcaggggagccgccgcagaaa gatgataacaacggtcctctgccagagactcctaaccgggctgagccagcctcccacaga ggtgccgacgataccgatcagcaaagaacttccgggccacccccacaccagaatccccca ggagactccctttcctctgatgacacctccccagcgccccaagccaatgcaacggggacc gcagacctgaagaccccagataccgatggcccgtcgtctccagccaagccccaggacccg cgagccagacccctctccaagaaagacgagaagcaggagcacatcaagaggcagctgatg accaactttatcctgggctccttcgatgacaactcctccgatgaggaccccagtgccggc ttgttccgagagtctccccggaagggcagccgggccagcctggggactctgtctctggag gctgctctaactgcaggcgagccggagaaccccgtccccaccataagacccagcatgtcc ggactccacctggtgaagaagggccgagaactaaagaaggtggacctgcacagagacttt accgtggcctccccggctgagtttgtcacgcgcttcgggggggatcgggtcattgagaag tctggggcctttaacctccaggacgcagaggcagccaagggggccagttcagagcacaga gtcttggtcaccctctcggtggccgtccgtagtcctgcagtgaccttcagcgtctcagtt tttctttcctttcctcatttaattgcagagtatatcaagatggcagatcagtacgtccct gtcccaggagggcccaacaacaacaactatgccaacgtggagctggttgtggacattgcc aagaggatccccgtgcaggcggtgtgggctggctggggccatgcttccgaaaaccccaaa ctcccggagctcctgtgcaagcatgagattgctttcttaggccctcccagtgaggccatg tgggccttgggagataagatcgcctccaccattgtggcccagacgctgcaggtcccaaca ctgccttggagtggaagtggtctgatgatagagtgggcagaagataatctgcaggagggg aaaagaatcagtgtcccagaagacatttacgaccagggttgtgtgaaagatgtggatgag ggcctagaggtggcagagaaaattggttttcccttgatgatcaaagcttctgaaggcggt ggagggaaaggaatccggaaagcagagagtgctgaggacttcccaatccttttcagacaa gtgcagagtgagatcccgggctccccgatctttctcatgaagctggcccagcacgcccgg cacctggaggtccagatcctcgccgaccagtacgggaacgccgtgtctctcttcgggcgt gactgctccatccagcggcggcatcagaagatcatcgaggaggcaccggccaccatcgcc acaccggctgtgttcgagttcatggagcagtgtgccgtccgcctggccaagaccgtgggc tacgtgagcgcggggacggtggaatacctctacagccaggatggcagcttccactttctg gagctgaatccccgcctgcaggtggagcacccgtgcacggaaatgatcgccgacgtcaac ctgccggccgcccagctacaggggtttaagccaagctccggaacggttcaggaactgaat ttccgcagcaacaagaatgtgtggggttatttcagcgtggctgctactggcggcttacat gaatttgcggattcccagttcgggcactgcttctcctggggagagaaccgggaagaggcc atttcgaacatggtggtggctttgaaggagctgtccatccggggcgacttcaggaccacc gtggagtatctcattaacctgctggagaccgagcgtttccagaacaatgacatcgacaca gggtggttggatcacctcatcgctgagaaagtgcaggctgagaagccagatatcatgctt ggggtggtgtgtggagccttgaacgtggccgatgtgatgttcagaacctgcatgacggat ttcctacactcgctggaaaggggccaggtccttcctgccgcttctctgctgaacatcgtg gatgtggaattaatttatgatggtgttaagtacattgtcaaggtggcccggcaatctctg accacgttcgtcctgatcatgaacggctgtcacatcgagatcgacgcccaccggctgaat gacggcgggttactgctgtcctacaatggcaacagctataccacctacatgaaagaagag gttgacagttaccgtgttaccattggcaacaagacctgtgtgtttgagaaggagaacgat cccacggtcctgaggtccccttcggccgggaagctaatacagtacacggtggaggacggg ggccacgtcgaggctgggagcagctacgcggagatggaggtgagcacagagcccgcccct ggggtgaggctgcagccgggtctcccctccccccactccccaagggaggaccatccgcca tcatccagtctacacctctcccctgggctgccacctgctgacctcctcagagagccagta tgtggggttcggcccaaattctctccagccgagccattcacaggagagctcccttcccag caaactctgcccatcattggagagaaactacaccaggttttccacaacgtcctggaaaac ctgaccaacgtcatgaatggctactgcctgccagagcctatttttagcacaaagctgaag gagtgggtgcagaaactcatgacgaccctgcggcacccgtccctgccgctgctggagctg caggagatcatgaccagcgtgtcgggccgcatccccgcccccgtggagaagtcggtccgc agggtgatggctcagtatgccagcaacatcacctcggtgctgtgccagttccccagccag cagatagccactatcctggactgccacgcggccaccctgcagcggaaggctgaccgggag gtgttcttcatgaacacccagagcatcgtgcagctggtccagaggtaccgcagcgggacc cgcggctacatgaaggcagtggtgttggatctcctgagaagatatttacgcgtggaacac catttccaacaagctcactacgacaagtgtgtgatcaacctcagggagcagctgaagcca aacatgtcccaggtgctggactgcatcttttcccacgcgcaggtggccaagaagaaccag ctggtgatcatgttgatcgatgagctctgtggcccagacccttccctgtcggaagagctg acctccatcctcaacgagctcactcagctgagcaaaagcgagcattgcaaagtggccctc agagcgagacagatcctgatcgcctcccacctcccgtcctacgagctgaggcacaaccag gtggagtccattttcctgtccgccatcgacatgtatggccaccagttctgcccggaaaac ctcaagaaattaatactgtcagagacgaccatattcgacgtcctgcccactttcttctac cacgctaacaaggtcgtttgcatggcgtccctggaggtttacgtgcgaaggggctacatc gcctacgagttaaacagcttgcagcaccggcagctcccagatggcacctgcgtggtagaa ttccagttcatgctgccctcctcccacccaaaccggtatggaaaaaacatccttgtggaa tatggactccgaagaatcacattcctgattgcccaagagaaagaatttccgaagtttttc acattcagagcaagagatgagtttgcagaagatcgcatttaccgtcacctggaacccgcc ctggccttccagctggagctcagccggatgcgcagcttcgatctgacggccgtgccctgc gccaaccacaagatgcatctgtacctgggcgccgccaaagtgaaagaaggcgcggaggtg acagaccacagattcttcatccgcgccatcatcaggcactcggacctcattacgaaggaa gcctcctttgagtacctgcagaacgagggtgagcgtctgctcctggaagccatggatgag ctggaggtggcgttcaacaacaccagtgtgcgcaccgactgcaaccacatcttcctgaac ttcgtgcccaccgtcatcatggaccccttcaagatcgaggagtccgtgcgttccatggtt atgcgctacggcagccggctgtggaaactccgcgtgctgcaggctgaggtcaagatcaac atccgcgagaccaccaccggcagtgctgttcccatccgcctgttcatcaccaacgaatcg ggctactacctggacatcagcctctacaaagaagtcaccgaccccagatctggaaacatc atgtttcactcctttggcaacaaacagggcccccagcacgggatgctgatcaacactccc tacgtcaccaaggatctgcttcaggccaagcgattccaggcccagtccctgggcaccacc tacgtgtatgacttcccggagatgttcaggcaggctctccttaaactgtggggctccaca gacgactaccccaaagacatcctgacatacaccgagcttgtgctggaccctcagggccag ctggtggagatgaaccgcctccctggaggaaatgaggtgggcatggtggccttcaagatg aggtttaagacccgagagtatccagaagggcgggacgcgatcgtcatcagcaatgacatc accttccgcattggatccttcggcctgggagaagaccttttgtatctgcgtgcgtctgag atggcccgggcggagggtatccccaaaatctacctcgcagccaacagcggggcctgtatc ggccttgcagaggagatcaagcacatgttccaggtggcttgggtggacccaggagacccc cacaaaggatttaaatacctgtacctgacgcctcaagactacaccagaatcagctcccta aactctgtccgttgtaaacacatcgaggaagagggagagtccaggtatgtcatcacggat atcatcgggaaggaccgtggcctgggcgtggagaacctcaagggctcgggcatgattgca ggggagtcctccctagcttacgaagagatcgtcaccatcagtatggtgacctgccgagcc cttgggatcggggcctacttggtgaggctgggccagcgagtgatccaggtggaaaattcg cacatcatcctgacgggagccagcgctctcaacaaggtcctgggcagagaggtttacacc tccaacaaccagctgggcggcgtgcagatcatgcatcacaacggcgtctcccacgtcact gtgccagacgacttcgagggcgtgtacaccatcctggagtggctgtcctatatgccaaag gataatcgcagtccagtccccatcaccacaccctcggaccccattgaccgagaaattgga ttcttcccgtccagggctccctacgacccccggtggctgcttgcaggacggcctcaccca actctgaagggatcctggcagagtggattctttgaccacggcagtttcaaggaaatcatg gcaccttgggcccagacggtggtgacaggaagagcgaggctaggggggatccctgttgga gtgatcgccgtggagacgcggaccgtggaggtggtagtgcctgcagaccctgccaacctg gattccgaggccaagataatccagcaggcgggccaggtgtggttcccagactcagcctac aagacggcccaggccatcaacgatttcaaccgagagggattgcccctgataatctttgcc aactggagggggttctccggtggcatgaaagacatgtacgaccaggtgctaaagtttgga gcctacatcgtggacagcctcaggcagtacaaacagcccgtcctgatctatatcccaccc cacggggaactccgggggggctcctgggtggtcgtggactcctccatcaaccccctgtgc atagaaacgtacgcagacaaggagagcagggcgagcattctggagccggagggaacagtg gagattaagttccgaaagaaagatctgataaagaccatgaggaggatcgacccagtttat aagaagctcgtggaacagctaggagtgtccgagctctccgataaggaccgcagggacctg gagggccagctgaaggcccgggaggacctgctcctgcccgtctaccaccaggtggcggtg ctgttcgccgacctccacgacagggcccacggcatgctggagaagggtgtcgtctctgta agagcctgcagctgtgggagccccacatga

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