Puma concolor (puma): 112871959 Help Entry 112871959         CDS       T08890                                  Symbol CASP8 Name (RefSeq) caspase-8   KO K04398   caspase 8 [EC:3.4.22.61] Organism pcoo  Puma concolor (puma) Pathway pcoo01524   Platinum drug resistance pcoo04115   p53 signaling pathway pcoo04210   Apoptosis pcoo04215   Apoptosis - multiple species pcoo04217   Necroptosis pcoo04620   Toll-like receptor signaling pathway pcoo04621   NOD-like receptor signaling pathway pcoo04622   RIG-I-like receptor signaling pathway pcoo04623   Cytosolic DNA-sensing pathway pcoo04625   C-type lectin receptor signaling pathway pcoo04657   IL-17 signaling pathway pcoo04668   TNF signaling pathway pcoo04932   Non-alcoholic fatty liver disease pcoo04936   Alcoholic liver disease pcoo05010   Alzheimer disease pcoo05016   Huntington disease pcoo05022   Pathways of neurodegeneration - multiple diseases pcoo05132   Salmonella infection pcoo05134   Legionellosis pcoo05142   Chagas disease pcoo05145   Toxoplasmosis pcoo05152   Tuberculosis pcoo05160   Hepatitis C pcoo05161   Hepatitis B pcoo05162   Measles pcoo05163   Human cytomegalovirus infection pcoo05164   Influenza A pcoo05165   Human papillomavirus infection pcoo05167   Kaposi sarcoma-associated herpesvirus infection pcoo05168   Herpes simplex virus 1 infection pcoo05169   Epstein-Barr virus infection pcoo05170   Human immunodeficiency virus 1 infection pcoo05200   Pathways in cancer pcoo05203   Viral carcinogenesis pcoo05416   Viral myocarditis pcoo05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:pcoo00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     112871959 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     112871959 (CASP8)    04215 Apoptosis - multiple species     112871959 (CASP8)    04217 Necroptosis     112871959 (CASP8)    04115 p53 signaling pathway     112871959 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     112871959 (CASP8)    04621 NOD-like receptor signaling pathway     112871959 (CASP8)    04622 RIG-I-like receptor signaling pathway     112871959 (CASP8)    04623 Cytosolic DNA-sensing pathway     112871959 (CASP8)    04625 C-type lectin receptor signaling pathway     112871959 (CASP8)    04657 IL-17 signaling pathway     112871959 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     112871959 (CASP8)    05203 Viral carcinogenesis     112871959 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     112871959 (CASP8)    05161 Hepatitis B     112871959 (CASP8)    05160 Hepatitis C     112871959 (CASP8)    05164 Influenza A     112871959 (CASP8)    05162 Measles     112871959 (CASP8)    05168 Herpes simplex virus 1 infection     112871959 (CASP8)    05163 Human cytomegalovirus infection     112871959 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     112871959 (CASP8)    05169 Epstein-Barr virus infection     112871959 (CASP8)    05165 Human papillomavirus infection     112871959 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     112871959 (CASP8)    05134 Legionellosis     112871959 (CASP8)    05152 Tuberculosis     112871959 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     112871959 (CASP8)    05142 Chagas disease     112871959 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     112871959 (CASP8)    05016 Huntington disease     112871959 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     112871959 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     112871959 (CASP8)    05416 Viral myocarditis     112871959 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     112871959 (CASP8)    04932 Non-alcoholic fatty liver disease     112871959 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     112871959 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:pcoo01002]     112871959 (CASP8) Enzymes [BR:pcoo01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      112871959 (CASP8) Peptidases and inhibitors [BR:pcoo01002]  Cysteine peptidases   Family C14: caspase family    112871959 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  112871959 NCBI-ProteinID:  XP_025790859 UniProt:  A0A6P6IST3 LinkDB All DBs Position Unknown AA seq 479 aa AA seqDB search MDFSKCLYNIGEQLGSDELASLKFLSLDYIPQKKQEPIKDALMLFQRLQEKRMLEESNLS FLKELLFRINRLDLLFNYLNTSKEAMEQELQIPGRAQIPPYRVMLFQISEDVNKLELRSF KFLLSQEISRCKVDDDMNLLDIFIEMEKRVILGERNLDTLKRICDQINKSLLKKITDYEE LSREGRMSLQRSPDELSNGEESLAMMALSDSLEEQDSESQTSDKVYRMKSKPRGYCLIFN NYDFSRARKDVPKLQNIKDRNGTDFDAEALSKTFSELHFEIVNFKDSTAKTICEVLKSYQ RMDHNNKDCFICCILSHGDKGIIYGSDGQEAPIYELTSYFTGSKCPSLAGKPKIFFIQAC QGDNYQRGIAVETDSEQKEDYLEMDSSFQKRYIPDEADFLLGMATVNNCVSYRNPTEGTW YIQSLCQSLRERCPRGEDILTILTEVNFEVSNKDDKKNMGKQMPQPTFTLRKKLFFPLN NT seq 1440 nt NT seq  +upstreamnt  +downstreamnt atggatttcagtaaatgtctgtataatattggggaacagttgggcagtgacgagctggcc tccctcaaattcctgagcctggactacatcccacaaaagaagcaagaacccatcaaagat gccttgatgttattccagagactccaggaaaagagaatgttggaggaaagcaacctgtcc ttcttgaaggagctgcttttccgaattaatagactggacctgctgttcaactacctgaac accagcaaggaagcgatggagcaggagcttcagataccaggcagagcccagatccctccc tacagggtcatgctttttcagatttcagaagatgtaaacaaattggaattgaggtcgttt aagtttcttttgagccaggagatctccagatgtaaagtggatgatgatatgaacttgctt gatattttcatagagatggaaaagagggtcatcctaggggaaagaaatttggacactctg aaaagaatctgtgaccaaatcaacaagagcctgctgaagaaaatcactgattatgaagaa ttaagcagagagggaagaatgagccttcaaagaagtccagatgaattgtcaaatggggag gaatccctggcaatgatggcattatcggactctctagaagaacaggacagtgagtcacag acatcggacaaagtttaccgaatgaaaagcaaacctcgcggatattgtttgatctttaac aattatgattttagcagagcacggaaggatgtgcccaaacttcagaacattaaggatagg aatggaacagacttcgatgcagaagctttgagtaagacctttagtgagcttcattttgag attgtgaatttcaaagactctacagcaaagacaatctgtgaagttctgaaatcctaccaa agaatggaccataataacaaagattgcttcatctgctgtatcctctcccatggagacaaa ggcattatttatggctctgatgggcaggaagcccctatctatgagctgacttcttacttc actggttcaaagtgcccttcccttgcaggcaagcccaaaatcttttttattcaggcttgt caaggggataactaccagagaggtatagctgttgagactgactccgaacagaaggaagac tacttagaaatggactcatcatttcagaagagatatatcccagatgaggctgattttctg ctggggatggccactgtgaacaactgtgtttcctaccgaaaccctacggaggggacctgg tatatccagtcactttgccagagcctaagagaaagatgtcctaggggcgaagatatcctc accatccttactgaggtgaactttgaagtgagcaataaggatgacaagaaaaacatgggg aaacaaatgccacaacctactttcacactgaggaaaaaactcttcttccctcttaattga

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