Propithecus coquereli (Coquerel's sifaka): 105810971
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Entry
105810971 CDS
T08746
Symbol
IRS4
Name
(RefSeq) insulin receptor substrate 4
KO
K17446
insulin receptor substrate 4
Organism
pcoq
Propithecus coquereli (Coquerel's sifaka)
Pathway
pcoq04022
cGMP-PKG signaling pathway
pcoq04068
FoxO signaling pathway
pcoq04081
Hormone signaling
pcoq04140
Autophagy - animal
pcoq04152
AMPK signaling pathway
pcoq04211
Longevity regulating pathway
pcoq04213
Longevity regulating pathway - multiple species
pcoq04910
Insulin signaling pathway
pcoq04920
Adipocytokine signaling pathway
pcoq04923
Regulation of lipolysis in adipocytes
pcoq04930
Type II diabetes mellitus
pcoq04935
Growth hormone synthesis, secretion and action
pcoq05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
pcoq00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
105810971 (IRS4)
04022 cGMP-PKG signaling pathway
105810971 (IRS4)
04152 AMPK signaling pathway
105810971 (IRS4)
09133 Signaling molecules and interaction
04081 Hormone signaling
105810971 (IRS4)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
105810971 (IRS4)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
105810971 (IRS4)
04923 Regulation of lipolysis in adipocytes
105810971 (IRS4)
04920 Adipocytokine signaling pathway
105810971 (IRS4)
04935 Growth hormone synthesis, secretion and action
105810971 (IRS4)
09149 Aging
04211 Longevity regulating pathway
105810971 (IRS4)
04213 Longevity regulating pathway - multiple species
105810971 (IRS4)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
105810971 (IRS4)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
105810971 (IRS4)
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Ortholog
Paralog
GFIT
Motif
Pfam:
IRS
PH_11
PH_8
PH
Motif
Other DBs
NCBI-GeneID:
105810971
NCBI-ProteinID:
XP_012500496
LinkDB
All DBs
Position
Unknown
AA seq
1271 aa
AA seq
DB search
MASCSFARDQATRRLRGAAAAAAAALTAVATTPLLSSGTPTALIGTGSSCPGAMWLSTAT
GSRSDSESEEEDLPVGAEVCKRGYLRKQKHGHRRYFVLKLETADAPARLEYYENARKFRH
SVRAAAAAAAAAASGSAVPALIPPRRVITLYQCFSVSQRADARYRYLIALFTQDEYFAMV
AENESEQESWYLLLSRLILESKRRRCGTLGAQPDGEPAALAAAAAAEPPFYKDVWQVIVK
PRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRST
VIGPGELWMQVDDCVVAQNMHELFLEKMRALCADEYRARCRSYSICIGAHLLTLLSTRRH
LGLLPLEPGGWLRRSRFDQFYHLRALGDGEDEMLFSRRFLTPSEPVPASRRGRPHLPRVR
WSRRAISVPACIFRRLSPSPVRAPNPAEAPNDGAGQSSEASGSGNSGEEGNPQGKEGQEG
REGDYMPMNNWGSGNGRGSGGGQGSSGQGSSSQSSGGNQCSGGGQGSRGGQGSSGSQGSS
GQGSGGNQCSGNGQGTAGGSGGGQGAGGGHGSGGGRGPGDGHGSGSGKNSGGGKSSGSGK
GAEGDGERGKSLKKRSYFGKLTQSKQQQMSGPPPPPPPPPPAGATGGKAKSGGRFRLYFC
ADKGATKERKEAKEVKHAEIPEGAARGPYRARAFDEDEDDPYVPMRPGVAAPLASSSDYM
PMAPQNVSASKRHSRSPFEDSRGYMIMFPRVNPPPVPSPPKTPDPNKEDDSKDNDSDSDY
MFMAPGAGAIPKNPKNAQGGSSSKSWSSYFSLPNPFRSSPLGQSDHSEYVPMLPGKFLGR
GLEKEVSSNWGPKHAASKLSVEGLFSKPGDRGAPSKPLDDGSPKNKAKRANRLSFITKGN
KIKPKPQKPTHEQREADGSSDYVNIDFTKRDSNRPVPFIQGLPDSWGIIADPRQSAFSNY
VNIEFGVPFLNSANHLLYLLRSVGPLFLYGARWPLRLIPYRATGSNANEEAGNYIEVIFN
PAMTPAVPFADSAIRYDAETGRIYVVDPFSECCMDISLSPSRCSEPLPVARLLQEEEQER
RRPQSRSQSFFAAARAAVSAFPTDSLEEELFASSASAAAFAAAPTLAVGRVLAAASALAA
APGIGSAAAGWEAAAGFDSASARWFQPVANAADAGAVRGTQNSALVSNLGAPNPPADLVR
GENGAGGALAAAAAAAAAAAAAAAAPPPPPRGPRVPRPPERGDSDDDDDDDTYVRMDFAR
PDNKFDSPKRE
NT seq
3816 nt
NT seq
+upstream
nt +downstream
nt
atggcgagttgctccttcgctcgcgaccaagcgacaaggagactgagaggtgcagcagca
gcagcagcggcggctctaacagcggtggcgaccaccccgcttctttcttcgggaacccca
accgcactcattgggaccgggtcgtcttgtccgggagccatgtggctctccacggccact
ggctcccggtcagactctgagtccgaagaggaggacctccccgtcggggccgaagtctgc
aaacggggctacctgcggaagcagaagcatgggcacaggcgctacttcgtgctcaaactc
gagaccgccgacgccccagctcggctggaatactacgaaaatgccaggaagttccgccac
agtgtccgcgccgcggcggctgcagctgcggcggccgcctcaggctccgcggtccccgcg
ctgattccaccgcggcgcgtgatcactctataccagtgcttctccgtgagccagcgagca
gatgcaaggtaccgctatctcattgcccttttcacccaggacgagtacttcgcaatggtg
gccgagaacgagtcggagcaggaaagctggtacttgctgctcagccgcctcatcctcgag
agcaagcgccgccgctgcggcacgctgggcgcgcagccggacggagagccggccgcgctg
gcggcggcagcggcggcggagccacccttctataaagatgtgtggcaggtaatagtcaaa
cccagggggctggggcacagaaaagagctgagcggcgtgttccggctctgtctaaccgac
gaggaggtcgtgtttgtgaggctgaacaccgaagtggccagtgtagtcgtccagctcctg
agcatccgtcgctgcgggcactcggagcagtatttcttcttggaagtcggcaggtccacc
gttatcggtccgggggagctctggatgcaggtcgatgactgtgtggtggcccaaaacatg
cacgagctgtttttggagaagatgagagccttgtgtgcagacgaatacagagcccgctgc
cgcagctacagcatctgcatcggcgcccacctgttaaccctgctgtccactaggaggcac
ctgggcttgctgccgctcgagcccggcggctggctcagaaggtcccgctttgaccagttt
taccacctcagagccctcggtgatggggaagacgagatgctcttctccagacgcttccta
acacccagcgagcctgtgcccgcctccaggcgaggaagaccgcacctgcccagagtgcgc
tggtccaggagagcgatttcagtgccagcctgcatttttcgccgcttatcacccagcccg
gtacgtgccccaaaccctgcagaagccccgaacgacggagctggccagtcttctgaagca
tctggctctggcaactctggggaggaaggcaatcctcagggcaaagaaggtcaggaagga
agggaaggtgactacatgcctatgaacaattggggctccggcaatggccggggctcagga
ggtggccagggctcaagtgggcaaggctccagtagccagagctcgggaggaaaccaatgt
tcaggtggcggacagggatccagaggtggccagggctctagcggcagccagggttcaagt
ggccagggctcaggaggaaaccagtgctcaggaaatggccagggcactgcaggtggctca
ggtggtggccagggagctggaggtgggcacggctcaggcggtggccggggacctggagat
ggacatggctcaggcagtggcaagaactctggcgggggcaagagctcaggaagtgggaaa
ggcgcggaaggtgatggtgaacgtggaaaatctctgaagaaaagatcctactttggcaaa
ttaactcaaagcaagcaacagcaaatgtcaggacctccaccacccccacctccacccccg
ccagctggagcaactggtggaaaagcgaagtctggaggaagattccgactttatttttgt
gctgacaaaggagccacgaaagaacgaaaagaagccaaagaagtgaaacacgcagagatc
ccagaaggtgcagctcgggggccctacagagccagagcttttgatgaagatgaagatgat
ccatatgtgccaatgaggccaggggtggctgcccctcttgcaagctccagcgattatatg
ccaatggctcctcaaaatgtctctgcttcaaaacgccattctcgatcaccttttgaagat
tcaagagggtacatgattatgtttcccagagtgaacccaccacctgttccaagtcctcca
aaaacacccgatcctaataaagaggatgactcaaaggacaatgacagtgacagtgactat
atgtttatggctcctggagcaggtgcaattccaaaaaaccccaagaatgctcaggggggc
tcttcctccaaaagttggagctcctacttctctctgccaaatccttttcggagctcccct
ttgggacagagtgaccacagtgagtatgtaccaatgttacctggaaagtttctggggagg
ggcctagaaaaagaagtctcatctaactggggccccaaacatgcagcttcaaagctgtca
gttgaggggttattctcaaagcctggagataggggagcaccttcaaagcctttggatgat
gggtccccaaagaataaggctaagagagctaaccgactttcttttattacaaaaggaaat
aaaatcaagccaaaaccacaaaagcccacacatgagcagagagaagctgacggctctagt
gactacgtcaacattgacttcactaaaagagatagcaataggccagttccctttattcaa
ggactgccagattcgtggggcataattgctgaccccagacagtcagccttttctaattac
gtgaatattgagttcggagtgccatttctaaattcagcaaaccacctcttatatctttta
agaagtgtcggccctctatttctgtacggcgctaggtggccacttcgtcttattccctac
cgtgccacaggtagcaatgctaatgaggaagctggtaactacattgaagtaattttcaac
ccagcaatgacaccagccgtgccttttgctgacagtgccattcgctatgatgctgaaact
ggtcgaatctacgtggtcgacccattttctgagtgctgtatggacatttctctgtctccc
agccgatgctctgagccactacctgtagctaggctgctgcaagaggaagagcaagagaga
agacgcccacaaagccgttcgcaaagtttctttgcagccgccagagccgctgtctcggct
tttcctaccgacagtctcgaggaagaactcttcgcttcctcagcctcggctgcggctttc
gcggccgcgccgaccttagccgtgggccgggttttagccgcggcctccgcgctcgccgcg
gccccgggcatcggttcagcagccgccggctgggaggcagcggctggatttgactccgcc
tccgcccgctggtttcaacctgttgctaatgctgctgatgccggagcggtaagggggacc
cagaatagcgcccttgtctcgaacctgggagccccaaacccacccgcagaccttgtcaga
ggtgaaaacggggcgggcggggctctcgctgccgccgccgccgccgctgccgccgccgcc
gctgctgctgctgctcccccaccaccacctcgcggtccccgggtgccaagacccccggag
agaggagattctgacgacgacgacgacgacgacacttacgtgagaatggactttgccaga
cctgacaacaaattcgactctcccaaaagagagtga
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