KEGG   Propithecus coquereli (Coquerel's sifaka): 105824793
Entry
105824793         CDS       T08746                                 
Symbol
GRB2
Name
(RefSeq) growth factor receptor-bound protein 2
  KO
K04364  growth factor receptor-bound protein 2
Organism
pcoq  Propithecus coquereli (Coquerel's sifaka)
Pathway
pcoq01521  EGFR tyrosine kinase inhibitor resistance
pcoq01522  Endocrine resistance
pcoq04010  MAPK signaling pathway
pcoq04012  ErbB signaling pathway
pcoq04014  Ras signaling pathway
pcoq04062  Chemokine signaling pathway
pcoq04068  FoxO signaling pathway
pcoq04072  Phospholipase D signaling pathway
pcoq04150  mTOR signaling pathway
pcoq04151  PI3K-Akt signaling pathway
pcoq04380  Osteoclast differentiation
pcoq04510  Focal adhesion
pcoq04517  IgSF CAM signaling
pcoq04540  Gap junction
pcoq04550  Signaling pathways regulating pluripotency of stem cells
pcoq04630  JAK-STAT signaling pathway
pcoq04650  Natural killer cell mediated cytotoxicity
pcoq04660  T cell receptor signaling pathway
pcoq04662  B cell receptor signaling pathway
pcoq04664  Fc epsilon RI signaling pathway
pcoq04714  Thermogenesis
pcoq04722  Neurotrophin signaling pathway
pcoq04910  Insulin signaling pathway
pcoq04912  GnRH signaling pathway
pcoq04915  Estrogen signaling pathway
pcoq04917  Prolactin signaling pathway
pcoq04926  Relaxin signaling pathway
pcoq04935  Growth hormone synthesis, secretion and action
pcoq05034  Alcoholism
pcoq05160  Hepatitis C
pcoq05161  Hepatitis B
pcoq05163  Human cytomegalovirus infection
pcoq05165  Human papillomavirus infection
pcoq05200  Pathways in cancer
pcoq05203  Viral carcinogenesis
pcoq05205  Proteoglycans in cancer
pcoq05206  MicroRNAs in cancer
pcoq05207  Chemical carcinogenesis - receptor activation
pcoq05208  Chemical carcinogenesis - reactive oxygen species
pcoq05210  Colorectal cancer
pcoq05211  Renal cell carcinoma
pcoq05213  Endometrial cancer
pcoq05214  Glioma
pcoq05215  Prostate cancer
pcoq05220  Chronic myeloid leukemia
pcoq05221  Acute myeloid leukemia
pcoq05223  Non-small cell lung cancer
pcoq05224  Breast cancer
pcoq05225  Hepatocellular carcinoma
pcoq05226  Gastric cancer
pcoq05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:pcoq00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105824793 (GRB2)
   04012 ErbB signaling pathway
    105824793 (GRB2)
   04014 Ras signaling pathway
    105824793 (GRB2)
   04630 JAK-STAT signaling pathway
    105824793 (GRB2)
   04068 FoxO signaling pathway
    105824793 (GRB2)
   04072 Phospholipase D signaling pathway
    105824793 (GRB2)
   04151 PI3K-Akt signaling pathway
    105824793 (GRB2)
   04150 mTOR signaling pathway
    105824793 (GRB2)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    105824793 (GRB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    105824793 (GRB2)
   04540 Gap junction
    105824793 (GRB2)
   04550 Signaling pathways regulating pluripotency of stem cells
    105824793 (GRB2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    105824793 (GRB2)
   04660 T cell receptor signaling pathway
    105824793 (GRB2)
   04662 B cell receptor signaling pathway
    105824793 (GRB2)
   04664 Fc epsilon RI signaling pathway
    105824793 (GRB2)
   04062 Chemokine signaling pathway
    105824793 (GRB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    105824793 (GRB2)
   04912 GnRH signaling pathway
    105824793 (GRB2)
   04915 Estrogen signaling pathway
    105824793 (GRB2)
   04917 Prolactin signaling pathway
    105824793 (GRB2)
   04926 Relaxin signaling pathway
    105824793 (GRB2)
   04935 Growth hormone synthesis, secretion and action
    105824793 (GRB2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    105824793 (GRB2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    105824793 (GRB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    105824793 (GRB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105824793 (GRB2)
   05206 MicroRNAs in cancer
    105824793 (GRB2)
   05205 Proteoglycans in cancer
    105824793 (GRB2)
   05207 Chemical carcinogenesis - receptor activation
    105824793 (GRB2)
   05208 Chemical carcinogenesis - reactive oxygen species
    105824793 (GRB2)
   05203 Viral carcinogenesis
    105824793 (GRB2)
   05231 Choline metabolism in cancer
    105824793 (GRB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    105824793 (GRB2)
   05225 Hepatocellular carcinoma
    105824793 (GRB2)
   05226 Gastric cancer
    105824793 (GRB2)
   05214 Glioma
    105824793 (GRB2)
   05221 Acute myeloid leukemia
    105824793 (GRB2)
   05220 Chronic myeloid leukemia
    105824793 (GRB2)
   05211 Renal cell carcinoma
    105824793 (GRB2)
   05215 Prostate cancer
    105824793 (GRB2)
   05213 Endometrial cancer
    105824793 (GRB2)
   05224 Breast cancer
    105824793 (GRB2)
   05223 Non-small cell lung cancer
    105824793 (GRB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    105824793 (GRB2)
   05160 Hepatitis C
    105824793 (GRB2)
   05163 Human cytomegalovirus infection
    105824793 (GRB2)
   05165 Human papillomavirus infection
    105824793 (GRB2)
  09165 Substance dependence
   05034 Alcoholism
    105824793 (GRB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    105824793 (GRB2)
   01522 Endocrine resistance
    105824793 (GRB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pcoq04131]
    105824793 (GRB2)
Membrane trafficking [BR:pcoq04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    105824793 (GRB2)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH3_3 SH2_2 DUF5093 DUF7145 hSH3 SH3_4
Other DBs
NCBI-GeneID: 105824793
NCBI-ProteinID: XP_012517831
Ensembl: ENSPCOG00000020735
UniProt: A0A2K6FUX3
LinkDB
Position
Unknown
AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq 654 nt   +upstreamnt  +downstreamnt
atggaagccatcgccaaatatgacttcaaagctactgcagacgatgagctgagcttcaaa
aggggggacatcctcaaggttttgaatgaagagtgtgatcagaactggtacaaggcagag
ctcaatggaaaggacggcttcatccccaagaactacatagaaatgaagccacatccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgcttagcaaacagcggcacgac
ggggcctttcttatccgagagagtgagagtgctcccggggacttctccctctctgtcaag
tttggaaatgacgttcagcacttcaaggtgctccgagatggagctggaaagtatttcctc
tgggtggtgaagttcaattctttgaatgagctggtagattatcacagatccacatctgtc
tccagaaaccagcagatattcctgcgggacatagaacaggtgccacagcagccaacatac
gtccaggccctctttgactttgacccccaggaggatggcgagctgggcttccgtcgggga
gactttatccacgtcatggataactcagaccccaactggtggaagggggcttgccacggg
cagaccggcatgtttccccgcaattacgtcaccccagtgaaccggaacgtctaa

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