KEGG   Propithecus coquereli (Coquerel's sifaka): 105825663
Entry
105825663         CDS       T08746                                 
Symbol
PTPN11
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 11 isoform X1
  KO
K07293  tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
Organism
pcoq  Propithecus coquereli (Coquerel's sifaka)
Pathway
pcoq04014  Ras signaling pathway
pcoq04072  Phospholipase D signaling pathway
pcoq04148  Efferocytosis
pcoq04360  Axon guidance
pcoq04517  IgSF CAM signaling
pcoq04625  C-type lectin receptor signaling pathway
pcoq04630  JAK-STAT signaling pathway
pcoq04650  Natural killer cell mediated cytotoxicity
pcoq04660  T cell receptor signaling pathway
pcoq04670  Leukocyte transendothelial migration
pcoq04722  Neurotrophin signaling pathway
pcoq04920  Adipocytokine signaling pathway
pcoq04931  Insulin resistance
pcoq05168  Herpes simplex virus 1 infection
pcoq05205  Proteoglycans in cancer
pcoq05208  Chemical carcinogenesis - reactive oxygen species
pcoq05211  Renal cell carcinoma
pcoq05220  Chronic myeloid leukemia
pcoq05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:pcoq00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    105825663 (PTPN11)
   04630 JAK-STAT signaling pathway
    105825663 (PTPN11)
   04072 Phospholipase D signaling pathway
    105825663 (PTPN11)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    105825663 (PTPN11)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    105825663 (PTPN11)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    105825663 (PTPN11)
   04650 Natural killer cell mediated cytotoxicity
    105825663 (PTPN11)
   04660 T cell receptor signaling pathway
    105825663 (PTPN11)
   04670 Leukocyte transendothelial migration
    105825663 (PTPN11)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    105825663 (PTPN11)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    105825663 (PTPN11)
  09158 Development and regeneration
   04360 Axon guidance
    105825663 (PTPN11)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    105825663 (PTPN11)
   05208 Chemical carcinogenesis - reactive oxygen species
    105825663 (PTPN11)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105825663 (PTPN11)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    105825663 (PTPN11)
   05211 Renal cell carcinoma
    105825663 (PTPN11)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    105825663 (PTPN11)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    105825663 (PTPN11)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:pcoq01009]
    105825663 (PTPN11)
Enzymes [BR:pcoq01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     105825663 (PTPN11)
Protein phosphatases and associated proteins [BR:pcoq01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    105825663 (PTPN11)
SSDB
Motif
Pfam: Y_phosphatase SH2 SH2_1 PTP-SAK Tc-R-P DSPc Y_phosphatase3 PTPlike_phytase PTP-NADK
Other DBs
NCBI-GeneID: 105825663
NCBI-ProteinID: XP_012518988
Ensembl: ENSPCOG00000027416
UniProt: A0A2K6GT86
LinkDB
Position
Unknown
AA seq 597 aa
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG
DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK
EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD
VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT
DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP
VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV
ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVW
QYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILI
DIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSK
RKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDNARVYENVGLMQQQKSFR
NT seq 1794 nt   +upstreamnt  +downstreamnt
atgacatcgcggagatggtttcacccaaatatcactggcgtggaggcagaaaacctactg
ttgacaagaggagttgatggcagtttcttggcaaggcccagtaaaagtaaccccggggac
ttcacactttccgttagaagaaatggagctgtcacccacatcaagattcagaacactggt
gattattacgacctgtacggaggggaaaagtttgccaccttggctgagttggtccagtat
tacatggaacatcatgggcaattaaaagagaagaatggagatgttattgagcttaaatat
cctctgaactgtgcagatcctacctctgaaaggtggttccacggacacctttctgggaaa
gaagcagagaaattactaactgaaaaaggaaagcacggtagctttcttgtccgagagagc
cagagccaccccggagatttcgttctctctgtgcgcaccggtgatgacaaaggggagagc
aatgacggcaaatctaaagtgacccacgtcatgattcgctgtcaggaactgaaatacgac
gttggtggaggagaacggtttgattctttgacggatctcgtggagcattacaagaagaat
cctatggtagaaacattgggcacagtactgcagctcaaacagcccctcaacacaactcgt
attaatgctgctgaaatagaaagcagggttcgagaactaagcaaattagctgagaccaca
gataaagtcaaacaaggcttttgggaagaattcgagacactacaacaacaggagtgtaaa
cttctctacagccgaaaagaaggtcaaaggcaagaaaataaaaacaaaaatagatataaa
aacatcctgccctttgatcataccagggttgtcctacatgacggcgatcccaacgagcct
gtttcagattacatcaatgcaaatattatcatgcccgaatttgaaaccaagtgcaacaat
tcaaagcccaaaaagagttatattgccacacaaggctgcctgcaaaacacggtgaatgac
ttttggcggatggtcttccaagagaactcccgagtgatcgtcatgacaacaaaagaagtg
gagagaggaaagagtaaatgtgtcaaatactggccagatgagtatgccctgaaagaatac
ggggtcatgcgcgttaggaacgtcaaagaaagtgccgcgcatgactatacattaagagaa
cttaaactttccaaggttggacaagctctactccaggggaatacggagagaaccgtctgg
cagtaccactttcggacctggccggaccacggagtgcccagtgaccccgggggcgtgctg
gacttcttggaggaggtccaccacaagcaggagagcatcatggacgcagggccagtcgta
gtgcactgcagtgctggaattggccggacagggacattcatagtgattgatatccttatt
gacatcatcagagagaaaggtgttgactgcgacattgacgttcccaagaccatccagatg
gtgcggtctcagaggtcagggatggtccagacagaagcacagtaccgatttatctatatg
gccgtccagcattatattgaaacactacagcgcaggattgaagaagagcagaaaagcaag
aggaaagggcacgagtatacaaatattaagtattctctagcggaccagaccagtggcgat
cagagccccctcccgccttgcaccccaacgccaccctgtgcagaaatgagagaagataat
gctagagtctatgaaaacgtgggcctgatgcagcagcagaaaagtttcagatga

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