Phascolarctos cinereus (koala): 110196696
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Entry
110196696 CDS
T05867
Symbol
IRS2
Name
(RefSeq) insulin receptor substrate 2 isoform X1
KO
K07187
insulin receptor substrate 2
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw04022
cGMP-PKG signaling pathway
pcw04068
FoxO signaling pathway
pcw04081
Hormone signaling
pcw04140
Autophagy - animal
pcw04152
AMPK signaling pathway
pcw04211
Longevity regulating pathway
pcw04213
Longevity regulating pathway - multiple species
pcw04910
Insulin signaling pathway
pcw04920
Adipocytokine signaling pathway
pcw04923
Regulation of lipolysis in adipocytes
pcw04930
Type II diabetes mellitus
pcw04931
Insulin resistance
pcw04932
Non-alcoholic fatty liver disease
pcw04935
Growth hormone synthesis, secretion and action
pcw05010
Alzheimer disease
pcw05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
110196696 (IRS2)
04022 cGMP-PKG signaling pathway
110196696 (IRS2)
04152 AMPK signaling pathway
110196696 (IRS2)
09133 Signaling molecules and interaction
04081 Hormone signaling
110196696 (IRS2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
110196696 (IRS2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
110196696 (IRS2)
04923 Regulation of lipolysis in adipocytes
110196696 (IRS2)
04920 Adipocytokine signaling pathway
110196696 (IRS2)
04935 Growth hormone synthesis, secretion and action
110196696 (IRS2)
09149 Aging
04211 Longevity regulating pathway
110196696 (IRS2)
04213 Longevity regulating pathway - multiple species
110196696 (IRS2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
110196696 (IRS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
110196696 (IRS2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
110196696 (IRS2)
04932 Non-alcoholic fatty liver disease
110196696 (IRS2)
04931 Insulin resistance
110196696 (IRS2)
BRITE hierarchy
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Ortholog
Paralog
GFIT
Motif
Pfam:
IRS
PH
PH_11
MEKK4_N
Mcp5_PH
Motif
Other DBs
NCBI-GeneID:
110196696
NCBI-ProteinID:
XP_020825717
UniProt:
A0A6P5IUC9
LinkDB
All DBs
Position
Unknown
AA seq
1451 aa
AA seq
DB search
MASPPLNGLLTPANSSSGGGGGGSGGGSGGGTNLNNNNNNNNHSVRKCGYLRKQKHGHKR
FFVLRGPGGGGEEQSGGGPGGQPPLPARLEYYENEKKWKNKSGAPKRVIALDSCLNINKR
ADAKHKYLIALYTKDEYFAVAAENEQEQEGWYRALTDLLNEGKAAYDSSTLYPHCLSSGA
SSASASSCSASLPGSGGSGSFGAAAEDLHYGLITPATAAYREVWQVNLKPKGLGQSKNLT
GVYRLCLSARTIGFVKLNCEVPSVTLQLMNIRRCGHSDSFFFIEVGRSASTGPGELWMQA
DDSVVAQNIHETILEAMKALKELFEFRPRSKSQSSGSSSTHPISVPGTRRHHHHHLVNLP
PSQTGLLRRSRTDSLAATPPAASNPIATQAPGAGKCSSCRVRTASEGDGSSGSGGGAGCR
PVSVAGSPMSPGPVRTPLSRSHTLSSSCSASMRPNKMMLAPAGGSLQHSRSTSMPVSHSP
PSATSPGSLSSSSGNGSASYSLPQGQHPHPHHLHLHQGQRPSSGSASASGSPSDPGFMSL
DEYGSSPGDLRAFCSNRSNTPESIAETPPARDGSGTELYGYMTMERPLSLCGRNYRRVSG
EGASDLDKGHRKRTYSLTTPARQRAVPQVSSASLDEYTLMRASFAGSSSRLYPASSPKVT
YNPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGVAPLAGGSIGSCKSDDYMPMSPTSV
SAPKQILQPRMAAASLAAGAASQAASSATSGRGSPLNGSSFKTSSPAESSPEDSGYMRMW
CGSKLSVESSEGKLLPNGDYLNMSPSDAGASLTPPDFFYDSVPLPGGGERPKGIPGCCYS
SLPRSYKTPCPRNGDSDQYVFMNSPVGRRIVEEEQEQPRLQPLPATATPCTQTTRPFVSN
GDSHSQPHHLVPSAVRQSGSSSGNNSRPESFLIQRCRAVRPTRLSLEGLRTLPSMHEYPL
PPEPKSPGEYINIDFSESGAHLSPPPPPLLTSAASSSSLLSASSPASSMGSGTPGTSGDS
RRRSPLSDYMNLGFGSPKSPKSGTEGGGSVGSLDALMSPEASSPCPPLPTPPASSSTSSS
QQQQLPPPPPPGELYRLPPASSTCHPAPVSSSSPSCPPESGDSGDYTEMAFGIAATPPQP
IAAPPKPESARVTSPTSGVKRLSLMEQVSGVEAFLLASPPPDPHRGAKVIRADPQGGRRR
HSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSGEGPSGSGGESLGGGEEEPSM
SPHLQQPSLPLPPQPQQLRWTQNQSGALVGCPGGSTSPMCRETSAGFQNGLNYIAIDVRD
EAGLLLQQQQQSGDKNTWARTRGLGGLINGGNGSNTGGCVGPGSGPLPTANTYASIDFMS
HHLKEATAVKDIYEISRKVSFPSCAKEGMLPLSVPTVYNASCIEKSLPLSAVPSTTVTVV
GEGKSDLTGQP
NT seq
4356 nt
NT seq
+upstream
nt +downstream
nt
atggccagcccgccactgaacgggctcctgaccccggcgaattcctccagcggaggagga
ggcggcggcagtggtggcggcagtggcggcggcaccaacctgaacaacaacaacaacaac
aacaaccacagcgtgcggaagtgcggctacctgaggaagcaaaaacacgggcacaaacgc
tttttcgtgctccggggccctgggggtggcggggaagagcagagcggtggggggcctggg
gggcagccacccctgcccgcgaggctggagtactacgagaatgagaaaaagtggaaaaac
aagtcgggggccccgaaaagggtgatcgccctagactcctgcctcaacatcaacaagcgg
gcggacgccaagcacaagtatctgatcgccctctataccaaggacgagtacttcgctgtg
gcagccgaaaatgagcaggagcaggagggctggtaccgggcgctcaccgacctgctcaac
gagggcaaagccgcttatgattccagcacgctctacccgcactgcctctcgtccggcgcc
tcgtcggccagcgcctcgtcctgcagcgcctccctgcctggctcgggcggcagcggctct
tttggggcagcggccgaggacctccactatgggctgatcaccccggccaccgcggcttac
cgggaggtctggcaggtgaacctgaagcccaaagggctgggacagagcaagaacctgacc
ggggtgtaccggctctgcctctccgcacgcaccattggttttgtgaagctcaactgcgag
gtgccgtcggtcactctgcagctgatgaacatccgacgctgcggccactcggacagcttc
ttcttcatcgaggtagggcgctcggcgtccacgggccctggcgagctctggatgcaggca
gatgactcagtggtggcccagaacatccacgaaaccatcctggaggccatgaaagctctg
aaggagctgttcgaattccgaccccgcagcaagagccagtcctcgggctcctcttccacc
caccccatcagcgtcccgggcacccggcgtcatcaccaccatcatttggtcaacctgcca
cccagccagactgggctccttcgccgatcccggaccgacagcctggccgccacgcctccc
gccgcgagtaaccccattgcgacccaggccccaggagctgggaagtgcagctcttgtagg
gtacgcacggccagcgagggggatggcagcagcgggagcggaggaggggcgggctgcagg
ccggtgtcagtggccggcagccccatgagtcccggcccggtgaggactcccctgagcagg
tcccatactctgagcagcagctgcagcgcctccatgcgacctaataagatgatgttagcc
cctgcaggaggctccctgcagcacagcagatccacgtctatgccggtatcccattcgcct
ccgtctgccaccagccctggcagcctgtcctccagcagcgggaatggctcagcttcttac
tccttgcctcaaggacagcatccacatccacaccaccttcacctccaccagggccagcgg
ccctctagtggcagtgcttctgcttctggctcccccagtgacccaggcttcatgtccttg
gatgaatatggctctagccctggggacctgcgggccttctgcagtaaccgaagcaacact
cctgagtctatagctgagaccccaccagcaagagatggtagtgggactgaactatatgga
tacatgaccatggagagacccctgagtctgtgtggccgaaactaccgaagggtgtccggg
gagggggcctcagacttggacaaaggtcacagaaagaggacttactctctgaccactcct
gctcgccaacgtgcagtaccccaggtgtcctctgcctctcttgatgaatatactctgatg
cgggccagttttgcaggcagctcaagccgcctttacccagcctcatctcccaaagtgacc
tacaacccatacccagaggactatggggacattgagattggctcccaccggagctccagc
agtaaccttggagcagatgatggctacatgcccatgactcctggagtggccccactggca
gggggcagcattggaagctgcaaaagtgatgactacatgcccatgagtcccaccagcgtc
tctgctcccaaacagatactacagccacggatggcagcagcctcccttgctgcaggtgca
gcctcccaggcagcctcatcagcaacaagcggtagaggctctccactgaatggcagcagc
ttcaagaccagttctccagctgaaagctctcctgaggacagtgggtacatgcgcatgtgg
tgcgggtccaagctgtcggtggaaagctctgagggcaagctacttcccaatggggattac
cttaacatgtcccctagtgatgctggagcttctctcaccccacctgacttcttctatgac
tcagtccccttgcctggtggtggagaacgacccaagggaatcccaggctgctgttacagc
tcactgccccggtcctacaagactccctgtcctcgaaatggggatagtgaccagtatgtc
ttcatgaattctccagtggggaggaggattgtggaagaggagcaagagcagccgaggctg
cagccactgcccgccacggctaccccctgcacccagaccaccaggccctttgtgtctaac
ggggacagccactcccagcctcaccacctagtgccttcagcagttaggcagagtggcagt
agcagtggcaacaacagccggccagagagtttcctcattcagcgttgcagagcagtccgg
ccaactcgtctgtccctggaggggcttagaaccctacctagcatgcatgagtaccctctg
ccacctgagcccaaaagcccaggtgagtacatcaacattgactttagtgagtctggagcc
cacctctcaccacctccacctcctctgctgacctcagcagcctcatcatcatcgctactc
tcagctagcagccccgcctcttcgatgggctcaggtacccctggcaccagtggtgacagc
cggaggcgttctcctctctctgattatatgaaccttggctttggctcacccaagtcaccc
aaatctggcactgagggtggtggctctgtgggctctttggatgccttgatgtcccctgag
gcctcctcgccctgcccaccactgccaacaccacctgcctcctcctctacttcttcctca
cagcagcagcaactaccacctccaccaccaccgggagagctataccgcctgcctccagct
tcttctacctgccacccagcccctgtttcttcctcctctccgtcttgtccccctgagtca
ggggatagtggtgactacaccgagatggccttcggcatagctgccactccaccacagccc
attgcagcccctccgaagccagaaagtgcccgggtgaccagccctacatctggtgtgaag
cggctgagtttgatggagcaggtgtctggtgtagaggccttcctgctggccagcccaccc
ccagacccacaccggggtgccaaggtcatccgtgctgacccacagggtggccgccgacgc
cacagctcggaaaccttttcctcgaccactactgtgacccctgtgtccccgtccttcgca
cacaatcctaagcgccacaactcggcctctgtggaaaatgtctctctcaggaaaagtggc
gaagggcccagtggcagtggtggtgagagtcttggaggaggtgaagaagagccgtctatg
tctccccaccttcagcagccttcgctccctctgccacctcagccccagcagctgaggtgg
acccaaaaccaatctggagcgttagtcggttgccctgggggcagtacctctcctatgtgt
cgggagacatcagcaggcttccagaatggtctcaactacattgccattgatgttagagat
gaagctggcctattgttgcagcagcagcagcagtctggagacaagaatacttgggcccgg
acccgtggcctgggtgggctcatcaatggtggaaatggcagcaacacaggtggttgtgtg
ggaccaggctctggacccttgcccacagccaacacctatgctagcattgactttatgtcc
catcatctgaaggaggctacagctgtgaaagatatctatgaaatatccaggaaagtctcc
tttccttcatgtgcaaaggagggtatgctgccactgtcagtccctactgtttataatgct
tcctgcattgaaaaatcactgccactcagcgcagttccttccactactgtgacagtagtt
ggagaagggaaatctgatttgactgggcagccctga
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