Phascolarctos cinereus (koala): 110197193 Help Entry 110197193         CDS       T05867                                  Symbol CASP8 Name (RefSeq) caspase-8   KO K04398   caspase 8 [EC:3.4.22.61] Organism pcw  Phascolarctos cinereus (koala) Pathway pcw01524   Platinum drug resistance pcw04115   p53 signaling pathway pcw04210   Apoptosis pcw04215   Apoptosis - multiple species pcw04217   Necroptosis pcw04620   Toll-like receptor signaling pathway pcw04621   NOD-like receptor signaling pathway pcw04622   RIG-I-like receptor signaling pathway pcw04623   Cytosolic DNA-sensing pathway pcw04625   C-type lectin receptor signaling pathway pcw04657   IL-17 signaling pathway pcw04668   TNF signaling pathway pcw04932   Non-alcoholic fatty liver disease pcw04936   Alcoholic liver disease pcw05010   Alzheimer disease pcw05016   Huntington disease pcw05022   Pathways of neurodegeneration - multiple diseases pcw05132   Salmonella infection pcw05134   Legionellosis pcw05142   Chagas disease pcw05145   Toxoplasmosis pcw05152   Tuberculosis pcw05160   Hepatitis C pcw05161   Hepatitis B pcw05162   Measles pcw05163   Human cytomegalovirus infection pcw05164   Influenza A pcw05165   Human papillomavirus infection pcw05167   Kaposi sarcoma-associated herpesvirus infection pcw05168   Herpes simplex virus 1 infection pcw05169   Epstein-Barr virus infection pcw05170   Human immunodeficiency virus 1 infection pcw05200   Pathways in cancer pcw05203   Viral carcinogenesis pcw05416   Viral myocarditis pcw05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:pcw00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     110197193 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     110197193 (CASP8)    04215 Apoptosis - multiple species     110197193 (CASP8)    04217 Necroptosis     110197193 (CASP8)    04115 p53 signaling pathway     110197193 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     110197193 (CASP8)    04621 NOD-like receptor signaling pathway     110197193 (CASP8)    04622 RIG-I-like receptor signaling pathway     110197193 (CASP8)    04623 Cytosolic DNA-sensing pathway     110197193 (CASP8)    04625 C-type lectin receptor signaling pathway     110197193 (CASP8)    04657 IL-17 signaling pathway     110197193 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     110197193 (CASP8)    05203 Viral carcinogenesis     110197193 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     110197193 (CASP8)    05161 Hepatitis B     110197193 (CASP8)    05160 Hepatitis C     110197193 (CASP8)    05164 Influenza A     110197193 (CASP8)    05162 Measles     110197193 (CASP8)    05168 Herpes simplex virus 1 infection     110197193 (CASP8)    05163 Human cytomegalovirus infection     110197193 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     110197193 (CASP8)    05169 Epstein-Barr virus infection     110197193 (CASP8)    05165 Human papillomavirus infection     110197193 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     110197193 (CASP8)    05134 Legionellosis     110197193 (CASP8)    05152 Tuberculosis     110197193 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     110197193 (CASP8)    05142 Chagas disease     110197193 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     110197193 (CASP8)    05016 Huntington disease     110197193 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     110197193 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     110197193 (CASP8)    05416 Viral myocarditis     110197193 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     110197193 (CASP8)    04932 Non-alcoholic fatty liver disease     110197193 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     110197193 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:pcw01002]     110197193 (CASP8) Enzymes [BR:pcw01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      110197193 (CASP8) Peptidases and inhibitors [BR:pcw01002]  Cysteine peptidases   Family C14: caspase family    110197193 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED Motif Other DBs NCBI-GeneID:  110197193 NCBI-ProteinID:  XP_020826549 UniProt:  A0A6P5J6C7 LinkDB All DBs Position Unknown AA seq 471 aa AA seqDB search MDFHTVLYNVAEEIDSRDLVGLKFLCLDHIPLKKQEFIKDAVGLFKILEEKGLLEEDNLF FLKELLYRDNRMDLLKLLNTNQQEVECQIQTTAQISSYRVLLFDLSENVAKFELKSIKFM LSRKIPKCKLEDNMTLIDIFIEMEKRGILGEGNLDDLKAVCDVIDKNLLEKIRKYESNRV ERSTERVPMEIQDVEEMMNDLQATSGDFPGEKDQDKAYKMSSKPRGYCLIINNFDFQRAR KEKPEHQNIRDRKGTDVDADALKNTFKELHFEIVHLQDRTAEQIHKDLQYYRDRNHDGKD CFICCLLSHGDRGTIYGIDGQEVAIKDLTSYFSSSKCPSLAGKPKVFFIQACQGKTIQSG ITLDTDSEQQRESLETDAFLQSECIPDEADFLLGMATVENHISYRHPKEGTWYIQSLCKN LKEKCPRGVAILDILTDVNSEVSQKIDPNNKGKQMPQPKYTLRKKLFFPTN NT seq 1416 nt NT seq  +upstreamnt  +downstreamnt atggacttccacacagttctgtacaacgttgcagaggaaatagacagtcgagatcttgtt ggtctgaaattcctctgcttggatcatatcccattgaagaagcaggaatttatcaaggat gccgtggggttgttcaaaatactggaggaaaagggtttgttggaggaggacaatctgttc ttcttgaaggaactgttgtaccgcgataaccgaatggatctcctaaagctcctgaacact aaccaacaggaggtggagtgtcaaatccaaaccacagcccagatttcttcctatagggtc ctgctttttgacctttcagaaaatgtggcaaaatttgaattgaaatctattaaatttatg ttgagtcgcaagattcccaagtgcaaactagaagataatatgaccttgatcgatattttc attgagatggagaaacggggaattctaggagaaggaaacctggatgacctgaaggcagtt tgtgatgtcattgacaagaacctgctggagaaaataagaaaatatgaatcaaacagagtg gaaagaagcacagaaagagttccaatggaaatccaggatgttgaagaaatgatgaatgat cttcaggcaacatctggagattttccaggagaaaaggaccaggacaaagcttacaaaatg agcagcaagcctcggggatactgcttgatcatcaacaactttgacttccaaagagcacgg aaggaaaagcctgagcaccagaacataagggacaggaaagggactgatgtagatgcagat gctctgaaaaacaccttcaaggagcttcattttgaaattgtacatttgcaagatcgcaca gcagagcaaatacacaaggacctacagtattaccgggacaggaaccacgatggcaaagat tgctttatttgctgcctcctgtcccatggggatagaggtaccatctacggcattgatggg caggaggtggccatcaaggatctgacatcgtatttctctagttccaagtgcccgtccctt gctggtaaacccaaagtattttttattcaagcttgtcaaggcaagaccatccagagtggg atcaccctcgatacagattctgagcagcaaagagaatctctggaaacagatgcatttctt cagagtgaatgcattccagatgaggccgactttttacttgggatggcaactgtggagaat catatctcttaccgacacccaaaggaggggacctggtacatacagtccctttgcaagaat ctgaaggaaaaatgtcctcgaggagtggctattcttgacatcctgacagatgtaaactct gaagtgagccaaaaaattgacccgaacaacaaagggaagcagatgccacaacctaaatac acccttaggaaaaaacttttctttcccactaactag

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