Phascolarctos cinereus (koala): 110197533 Help Entry 110197533         CDS       T05867                                  Symbol ADCY1 Name (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism pcw  Phascolarctos cinereus (koala) Pathway pcw00230   Purine metabolism pcw01100   Metabolic pathways pcw01522   Endocrine resistance pcw04015   Rap1 signaling pathway pcw04020   Calcium signaling pathway pcw04022   cGMP-PKG signaling pathway pcw04024   cAMP signaling pathway pcw04062   Chemokine signaling pathway pcw04072   Phospholipase D signaling pathway pcw04081   Hormone signaling pcw04082   Neuroactive ligand signaling pcw04114   Oocyte meiosis pcw04211   Longevity regulating pathway pcw04213   Longevity regulating pathway - multiple species pcw04261   Adrenergic signaling in cardiomyocytes pcw04270   Vascular smooth muscle contraction pcw04371   Apelin signaling pathway pcw04540   Gap junction pcw04611   Platelet activation pcw04713   Circadian entrainment pcw04714   Thermogenesis pcw04720   Long-term potentiation pcw04723   Retrograde endocannabinoid signaling pcw04724   Glutamatergic synapse pcw04725   Cholinergic synapse pcw04727   GABAergic synapse pcw04750   Inflammatory mediator regulation of TRP channels pcw04911   Insulin secretion pcw04912   GnRH signaling pathway pcw04913   Ovarian steroidogenesis pcw04914   Progesterone-mediated oocyte maturation pcw04915   Estrogen signaling pathway pcw04916   Melanogenesis pcw04918   Thyroid hormone synthesis pcw04921   Oxytocin signaling pathway pcw04923   Regulation of lipolysis in adipocytes pcw04925   Aldosterone synthesis and secretion pcw04926   Relaxin signaling pathway pcw04927   Cortisol synthesis and secretion pcw04928   Parathyroid hormone synthesis, secretion and action pcw04934   Cushing syndrome pcw04935   Growth hormone synthesis, secretion and action pcw04970   Salivary secretion pcw04971   Gastric acid secretion pcw04972   Pancreatic secretion pcw04976   Bile secretion pcw05032   Morphine addiction pcw05142   Chagas disease pcw05146   Amoebiasis pcw05163   Human cytomegalovirus infection pcw05166   Human T-cell leukemia virus 1 infection pcw05200   Pathways in cancer pcw05207   Chemical carcinogenesis - receptor activation pcw05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:pcw00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     110197533 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     110197533 (ADCY1)    04371 Apelin signaling pathway     110197533 (ADCY1)    04020 Calcium signaling pathway     110197533 (ADCY1)    04072 Phospholipase D signaling pathway     110197533 (ADCY1)    04024 cAMP signaling pathway     110197533 (ADCY1)    04022 cGMP-PKG signaling pathway     110197533 (ADCY1)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     110197533 (ADCY1)    04081 Hormone signaling     110197533 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     110197533 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     110197533 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     110197533 (ADCY1)    04062 Chemokine signaling pathway     110197533 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     110197533 (ADCY1)    04923 Regulation of lipolysis in adipocytes     110197533 (ADCY1)    04912 GnRH signaling pathway     110197533 (ADCY1)    04913 Ovarian steroidogenesis     110197533 (ADCY1)    04915 Estrogen signaling pathway     110197533 (ADCY1)    04914 Progesterone-mediated oocyte maturation     110197533 (ADCY1)    04921 Oxytocin signaling pathway     110197533 (ADCY1)    04926 Relaxin signaling pathway     110197533 (ADCY1)    04935 Growth hormone synthesis, secretion and action     110197533 (ADCY1)    04918 Thyroid hormone synthesis     110197533 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     110197533 (ADCY1)    04916 Melanogenesis     110197533 (ADCY1)    04925 Aldosterone synthesis and secretion     110197533 (ADCY1)    04927 Cortisol synthesis and secretion     110197533 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     110197533 (ADCY1)    04270 Vascular smooth muscle contraction     110197533 (ADCY1)   09154 Digestive system    04970 Salivary secretion     110197533 (ADCY1)    04971 Gastric acid secretion     110197533 (ADCY1)    04972 Pancreatic secretion     110197533 (ADCY1)    04976 Bile secretion     110197533 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     110197533 (ADCY1)    04727 GABAergic synapse     110197533 (ADCY1)    04725 Cholinergic synapse     110197533 (ADCY1)    04720 Long-term potentiation     110197533 (ADCY1)    04723 Retrograde endocannabinoid signaling     110197533 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     110197533 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     110197533 (ADCY1)    04213 Longevity regulating pathway - multiple species     110197533 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     110197533 (ADCY1)    04714 Thermogenesis     110197533 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     110197533 (ADCY1)    05207 Chemical carcinogenesis - receptor activation     110197533 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     110197533 (ADCY1)    05163 Human cytomegalovirus infection     110197533 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     110197533 (ADCY1)    05142 Chagas disease     110197533 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     110197533 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     110197533 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     110197533 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     110197533 (ADCY1) Enzymes [BR:pcw01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      110197533 (ADCY1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom Peptidase_M48 LDcluster4 Motif Other DBs NCBI-GeneID:  110197533 NCBI-ProteinID:  XP_020827202 UniProt:  A0A6P5IYJ8 LinkDB All DBs Position Unknown AA seq 1129 aa AA seqDB search MHGTDMEETPFRKVKTKRRKCPPCGCAPPGGSPVLLEAIACEDEFDCKELESLFRNYNLK LEQTSTLKALAVLIVLTGTLALGELMSGPNLTISKGSHPVHCIIFLSLFIVTNVKYLQVT QLQQIVKLILLFSFTFAFLCCPFSLGAYGIEPPTSPEQGMWQLMLVTFVSYSLLPVRSLL AIIFGIVVSVSHLIVTATSVTAKRHRLWRTLGANALLFVSVNLYGVFVRILTERAQRKAF LQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVS ILFADIVGFTSLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQP KTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDV TLANVMETGGLPGKVHITKTTLECLNGDYEVEPGFGHERNSFLKKHNIETFFIVPSHRRK IFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRALRTAS EKLRNRSSFSTNIVYTTPGTRVNRYISRLIEARQTESEMADLNFFTLQYKHKEREEKYHQ LQDEYFTSAVVLSLVLAALFGLVYLLIIPQSIIVLVLLVFCICFLVACIMYLHVTRVQCF PGCLTIQIRTVLCVFIVILLYSVAQGCVVGCMPWSWNTNSSRSLVIISSGGMNKTRNVLP CDTAHHAFLSCIVGTLTLAIFLRVSSLPKMILLFLVTVLYILVLELSGYRKAVGGGTFYL RGYEPILAILLFSCALALHARQVDLKLRLDYLWAVQAEEERDDMERVKLDNKRILFNLLP AHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIA DFDELMDKEFYKDLEKIKTIGSTYMAAVGLVPTTGTRAKKSIYSHLSTLADFAIEMFDVL DEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGKIQVTE EVHRLLKRCSYEFTCRGKVSVKGKGEMLTYFLEGKANGSNSQTRSLNLERKMYPYGKSNI QTKLGTSCPSVSSVASFTVKAGIGALQTAGTHTNPTLHYLPSVPAVKEA NT seq 3390 nt NT seq  +upstreamnt  +downstreamnt atgcatggcactgacatggaggaaacaccgtttcggaaagtcaaaacgaagaggaggaag tgtccaccctgtggctgcgccccgccggggggctccccggtgcttctggaggccatcgcg tgcgaggacgagttcgactgcaaggagctcgagtcccttttccggaattacaacctgaaa ctggaacagacctccacgctcaaggcgctggccgtgctcatcgtcctgacgggtaccctg gccctgggggagctcatgtccggccccaacctgaccatctccaagggctctcaccccgtg cattgcatcatctttctctccctcttcatcgttaccaatgtcaagtacctacaggtcacc cagctccagcaaatcgtcaaactcatactgctcttcagtttcaccttcgccttcctctgc tgccctttttcgctgggggcctacggcatcgagcctcccacctccccagagcagggaatg tggcaactcatgctggtcaccttcgtttcctattccctgctgccggtgcggagcctgctg gccatcatctttgggatagtggtgtccgtctcgcacctcatcgtcactgccacttcagtg actgccaaaagacacagactctggaggacgcttggggcaaatgctctgctttttgtcagt gtaaatttgtatggggtctttgtgaggattttgacagaaagggctcagaggaaggctttc ctacaggccagaaactgcatagaggacaggctgaggctggaagatgaaaatgaaaaacag gaacggctcctgatgagtcttttgcccagaaatgttgccatggaaatgaaggaagatttt ctgaagccacctgagagaatttttcacaagatttacattcaaaggcatgacaatgtcagc attttgtttgcagatattgtgggcttcactagtttggcatcccagtgcactgctcaagag ctggtgaagcttctgaatgaactctttgggaagtttgatgaattggccactgaaaaccac tgcagacgaattaaaatcctgggggactgctactattgtgtgtcaggactgacccagccc aaaaccgaccatgcccactgctgtgtcgaaatggggctggacatgattgataccatcacg tctgttgcagaagccactgaagttgacctcaacatgcgagtgggcctgcatacaggccgt gtcctgtgtggggtgctaggacttcgaaagtggcaatatgatgtctggtcaaatgacgtg actctagcaaatgtcatggagactggaggattacctgggaaggttcatatcacaaagacc accttagagtgcctaaatggggactatgaggtagaaccaggttttggacatgagaggaac agtttcttgaaaaaacataatatcgaaaccttttttattgtaccatcccatcggagaaag atatttcctggacttattctctcagatataaaaccagccaaaaggatgaagttcaaaacg gtctgttacttattggtccagctaatgcactgtcggaagatgtttaaagcagaaatcccg ttctccaatgtcatgacctgtgaggatgatgacaagaggagggcattaaggacagcatct gaaaaactcaggaatcgatcttctttttctacaaacattgtctacaccaccccaggaact cgagttaacagatatatcagccgtttaatagaagcccggcaaacagagtctgagatggca gacttgaatttctttaccctacagtacaaacataaagaacgggaagaaaaatatcaccag cttcaagatgagtatttcaccagtgctgtggtcctttcacttgttctagctgccttattt ggccttgtctaccttctaataatcccacagagtatcatcgtcctggttctcctggtgttc tgcatatgcttcctagtggcttgtattatgtatctacacgtcacacgagttcagtgtttt ccagggtgcctgacaattcaaattcgtactgttttatgtgttttcatcgtaattttactt tactctgtggctcaaggatgtgtggtgggctgcatgccttggtcatggaacactaattcc agcagatccttagtgattatttcttctggaggaatgaataagacaaggaatgtcctgccc tgtgacacagcccatcacgcattcctttcctgcattgtggggactttgacactggcaata tttctccgtgtctcttcattgccaaaaatgatccttctctttttggttacagtcttgtat atacttgttttggagctcagtgggtacagaaaagcagtggggggtggcaccttttacctc cgtggatatgaacccatattggctattttgctgttttcctgtgctctggcccttcatgcc aggcaggtggacttgaagttacgtctggactacctctgggctgtgcaggcagaagaagag cgagatgatatggagagagtgaaactggacaataagaggattctcttcaaccttttgcca gcccatgttgcacaacactttcttatgtccaatcccaggaacatggacctttattaccag tcctattcacaagtgggcgtgatgtttgcttccatcccaaatttcaatgatttctacatc gaactggatggcaataacatgggagtggagtgtttacgcctattaaatgaaattattgct gattttgatgagctcatggacaaagaattttataaggacctagaaaagatcaagacaatt ggaagtacatatatggctgcagtgggattggtgccaaccacagggaccagggccaagaag tcaatttattcacatctgagcacactagccgattttgcaatagagatgttcgatgtcctt gatgaaatcaactaccaatcttacaacgactttgtcctccgtgttggcattaatgtaggt ccagtagtggcaggtgttattggtgccagaagacctcaatatgatatctggggaaacact gtaaatgttgccagccgaatggatagtactggagtgcaggggaaaattcaggtcacagaa gaagtccaccgattactaaagcggtgtagctatgaatttacgtgtcgagggaaagtcagt gtcaagggaaaaggtgaaatgttgacctattttctggaaggaaaagcaaacggtagtaat tctcaaaccaggtccttaaacttagaacggaaaatgtatccatatgggaaatcaaacatt cagacaaaactgggtactagctgcccttctgtctcatctgtggctagctttacggtcaaa gctgggattggagccctgcagacagcaggcacccacaccaatccaacgctccattacctt ccttctgtgccagctgtgaaagaagcctag

DBGET integrated database retrieval system