Phascolarctos cinereus (koala): 110206265 Help Entry 110206265         CDS       T05867                                  Symbol LCK Name (RefSeq) tyrosine-protein kinase Lck   KO K05856   lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2] Organism pcw  Phascolarctos cinereus (koala) Pathway pcw04064   NF-kappa B signaling pathway pcw04380   Osteoclast differentiation pcw04650   Natural killer cell mediated cytotoxicity pcw04658   Th1 and Th2 cell differentiation pcw04659   Th17 cell differentiation pcw04660   T cell receptor signaling pathway pcw05135   Yersinia infection pcw05166   Human T-cell leukemia virus 1 infection pcw05235   PD-L1 expression and PD-1 checkpoint pathway in cancer pcw05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:pcw00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     110206265 (LCK)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     110206265 (LCK)    04660 T cell receptor signaling pathway     110206265 (LCK)    04658 Th1 and Th2 cell differentiation     110206265 (LCK)    04659 Th17 cell differentiation     110206265 (LCK)   09158 Development and regeneration    04380 Osteoclast differentiation     110206265 (LCK)  09160 Human Diseases   09161 Cancer: overview    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     110206265 (LCK)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     110206265 (LCK)   09171 Infectious disease: bacterial    05135 Yersinia infection     110206265 (LCK)   09163 Immune disease    05340 Primary immunodeficiency     110206265 (LCK)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:pcw01001]     110206265 (LCK)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:pcw03036]     110206265 (LCK) Enzymes [BR:pcw01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      110206265 (LCK) Protein kinases [BR:pcw01001]  Non-receptor tyrosine kinases   SRC family    110206265 (LCK) Chromosome and associated proteins [BR:pcw03036]  Eukaryotic type   Centrosome formation proteins    Kinases and associated factors     110206265 (LCK) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_2 SH3_9 SH2_1 ABC1 SH3_16 Haspin_kinase Kdo SH3_3 RIO1 Motif Other DBs NCBI-GeneID:  110206265 NCBI-ProteinID:  XP_020839176 UniProt:  A0A6P5K2T3 LinkDB All DBs Position Unknown AA seq 509 aa AA seqDB search MGCSCSSSLDEDWMENIDVCERCHYPIVPLDAKGTLPMRNGSDVRDPLVTYEGLNPPVSP LQDNLVIALHSYKPSHDGDLGFEKGEQLRILEQNGEWWKAQSLTTGQEGYIPFNFVAKAN SLEPEPWFFKDLSRKDAERQLLAPGNTHGSFLIRESETTAGSFSLSVRDFDQNQGEVVKH YKIRNLDNGGFYISPRITFPNLHELVQHYSKVSDGLCTRLSRPCQTQKPQKPWWEDEWEV PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKAGSMSPDAFLAEANLMKQLQHQRL VRLYAVVTQEPIYIITEYMENGSLVDFLKTTTGVKLTIHKLLDMAAQIAEGMAFIEERNY IHRDLRAANILVSDTLNCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK SDVWSFGILLTEIVTYGRIPYPGMTNPEVIQNLEQGYRMVRPDNCPEELYKLMMLCWKER PEERPTFDYLRSVLEDFFTATEGQYQPQP NT seq 1530 nt NT seq  +upstreamnt  +downstreamnt atgggctgctcctgcagctccagcctcgatgaggactggatggaaaatatcgacgtgtgt gaacgatgccactaccctatcgtcccattggatgccaagggcacgctcccaatgaggaat ggttctgatgtacgggatcccttggtcacctatgagggtttaaacccacctgtgtctccg ttacaagataacctggtcatcgccctgcacagttataagccctcccatgatggggacctg ggctttgagaagggggagcagctgaggattctggaacagaatggagaatggtggaaggca cagtccttgaccactggccaggagggctacattcccttcaactttgtggccaaagcaaac agcctggagcctgagccttggtttttcaaggacctgagccggaaggatgctgagagacaa cttttggcccctggaaatacccacggatccttcctgatcagagagagcgagaccactgca ggctccttctctctgtctgtgcgggactttgaccagaaccagggggaggtggtgaaacat tacaagatccgcaacctggacaatggcggcttctacatttccccccgaatcacctttcct aatctgcatgagttggtccagcattattccaaagtctcagatgggctatgcactcgactg agccggccctgccagacccaaaagccacagaagccctggtgggaagacgagtgggaggtt ccaagagagacactgaagctggtcgagaggctgggagctggccagtttggggaggtttgg atggggtactacaatgggcataccaaggtagctgtgaaaagcctgaaagcgggcagcatg tctcctgatgccttcctggccgaggccaacctgatgaaacagttgcagcaccagcggctg gtacgcctttatgccgtggtcacacaggagcccatctacatcatcactgagtacatggag aatggaagcctggtagacttcctcaaaaccacaactggagtcaaactaaccatccacaaa ttgctggatatggctgcacagattgccgagggcatggccttcattgaagagcgcaattac attcaccgggaccttcgggcagccaacattctggtatcagacacactgaactgtaagatt gctgactttgggttggcccggctaattgaggacaatgaatacacggccagggaaggagca aaatttcccatcaagtggacagctcctgaggccatcaactatgggacatttaccattaag tcagatgtctggtcttttggcatcctgctcacagaaatcgtcacctatgggaggatcccc tacccaggaatgaccaaccctgaggtgattcagaatctggagcagggctatcgaatggtg aggcctgacaactgcccagaagagctatacaaactgatgatgctgtgctggaaggagagg cctgaggaacggcccacctttgactacctgaggagtgtcttagaagacttcttcactgcc actgagggccagtaccagccccagccatga

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