Phascolarctos cinereus (koala): 110207655
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Entry
110207655 CDS
T05867
Symbol
ROCK2
Name
(RefSeq) rho-associated protein kinase 2 isoform X1
KO
K17388
Rho-associated protein kinase 2 [EC:
2.7.11.39
]
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw04022
cGMP-PKG signaling pathway
pcw04024
cAMP signaling pathway
pcw04062
Chemokine signaling pathway
pcw04071
Sphingolipid signaling pathway
pcw04270
Vascular smooth muscle contraction
pcw04310
Wnt signaling pathway
pcw04360
Axon guidance
pcw04510
Focal adhesion
pcw04520
Adherens junction
pcw04530
Tight junction
pcw04611
Platelet activation
pcw04670
Leukocyte transendothelial migration
pcw04810
Regulation of actin cytoskeleton
pcw04921
Oxytocin signaling pathway
pcw05132
Salmonella infection
pcw05135
Yersinia infection
pcw05163
Human cytomegalovirus infection
pcw05200
Pathways in cancer
pcw05205
Proteoglycans in cancer
pcw05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
110207655 (ROCK2)
04071 Sphingolipid signaling pathway
110207655 (ROCK2)
04024 cAMP signaling pathway
110207655 (ROCK2)
04022 cGMP-PKG signaling pathway
110207655 (ROCK2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
110207655 (ROCK2)
04520 Adherens junction
110207655 (ROCK2)
04530 Tight junction
110207655 (ROCK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
110207655 (ROCK2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
110207655 (ROCK2)
04670 Leukocyte transendothelial migration
110207655 (ROCK2)
04062 Chemokine signaling pathway
110207655 (ROCK2)
09152 Endocrine system
04921 Oxytocin signaling pathway
110207655 (ROCK2)
09153 Circulatory system
04270 Vascular smooth muscle contraction
110207655 (ROCK2)
09158 Development and regeneration
04360 Axon guidance
110207655 (ROCK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110207655 (ROCK2)
05205 Proteoglycans in cancer
110207655 (ROCK2)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
110207655 (ROCK2)
09171 Infectious disease: bacterial
05132 Salmonella infection
110207655 (ROCK2)
05135 Yersinia infection
110207655 (ROCK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
110207655 (ROCK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcw01001
]
110207655 (ROCK2)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
pcw03036
]
110207655 (ROCK2)
Enzymes [BR:
pcw01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
110207655 (ROCK2)
Protein kinases [BR:
pcw01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
110207655 (ROCK2)
Chromosome and associated proteins [BR:
pcw03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
110207655 (ROCK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH
C1_1
APH
NPV_P10
Pkinase_C
Motif
Other DBs
NCBI-GeneID:
110207655
NCBI-ProteinID:
XP_020841053
UniProt:
A0A6P5K6J6
LinkDB
All DBs
Position
Unknown
AA seq
1400 aa
AA seq
DB search
MSQPPAEKMSGSAEVVPWDWAFANRQRLLEALLWDPRSPIYVESLLDGITSLYFDLNFPA
LRKNKNIDNFLIRYERTVTKIGCLQMKAEDFDVIKVIGRGAFGEVQLVRHKESQNVYAMK
LLSKFEMIKRSDSAFFWEERDIMAFANSPWIVQLFCAFQDDRYLYMVMEYMPGGDLVNLM
SNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKNGHLKLADFGTCMKMDE
TGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVG
TYSKIMDHKNSLNFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIKQHSFFKSDQWNW
DNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYSENLL
LGDSPSSCTENDSVQSRKNEQSVQIQKKLYLLEEHLKNEIQAKEDLDQKCKLVNTRLEKI
TKELEEEVTSRKNVESALRQLEREKALLQHKNTEYQRKAEHEADKKRNLENDVNSLKDQL
EDLKKRNQNSQISNEKVNQLQRQLDEANALLRTESDTASRLRKNQTESSKQIQQLESNNR
ELQDKNCTLENAKLKLEKDFINLQSALESERRDRTHGSEIINDLQGRISGLEEDIKNGKI
SLAKMELEKRQLQERFTDLEKEKSNMEIDMTYKLKVIQQSLEQEEAEHKATKARLADKNK
IYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSMLDCDLKQSQQKVNELLK
QKDKLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQMKQENNHLMEIKMS
LEKQNIELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECQEKTKLCKEMQQK
SQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQE
LAEKDATIASLEEANRTLTSDVANLANEKEELNNKVKEVQEQMSKLKDEETNISVIKTQF
EKQLLNERTLKTQAVNKLAEIMNRKEPPRRGADTDVRRKEKENRKLHMELKSEREKLTQQ
MIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPG
EAEADDGFPGTESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPYM
VLDIDKLFHVRPVTQTDVYRADSKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNCICH
KGHEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCKVY
YDISSAKNLLLLANSTEDQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKVQPNQSIRRP
SRQLPPSKPSSGPPLRIILH
NT seq
4203 nt
NT seq
+upstream
nt +downstream
nt
atgagccagccgccggccgagaaaatgtctggcagcgcggaggtagtgccctgggactgg
gccttcgcgaaccgccagcggctgctggaggccctgctctgggacccccgctcccccatc
tacgtggagagcctcctggatggtataacttccttgtactttgatctgaattttcctgct
ctgaggaaaaacaagaatatagacaatttcttaattagatatgagagaactgtgacaaaa
attggatgcctacagatgaaggcagaagattttgatgttattaaagtaattggaagaggt
gcttttggtgaagttcagttggttcgtcataaagagtcacagaatgtttatgccatgaag
cttcttagtaaatttgaaatgataaaaagatcagattctgcttttttttgggaagaacga
gatatcatggcctttgctaatagtccctggattgttcagctcttttgtgcctttcaagat
gatagatatctttatatggtaatggaatacatgcctggtggagaccttgtaaaccttatg
agtaactatgacgtacctgaaaaatgggccaaattttacacagctgaagttgttctggct
ttggatgcaatacactccatgggtttaatacacagagatgtgaaacctgacaacatgctt
ttggataaaaatggacatctgaaattagcagattttggcacttgtatgaaaatggatgaa
acaggcatggtacgttgtgatacagcagttggaacacctgattacatatcacctgaagtt
ttgaagtcacagggtggtgatggctactatggacgagagtgtgattggtggtctgtaggt
gttttcctttttgagatgcttgttggggatactccattttatgcagattcacttgtggga
acatatagtaaaattatggatcataaaaattcactcaatttcccagaagatgcagaaata
tccaagcatgcaaaaaatctcatatgtgctttcttgaccgacagggaggtgcgacttggg
agaaatggggtagaagaaatcaaacagcattctttctttaaaagtgatcagtggaattgg
gataacataagagagactgcagctccagtagtacctgaactcagcagtgacatagatagc
agcaattttgatgacattgaagatgataaaggagacgtggaaacctttccaattcctaaa
gcctttgtgggaaaccagctgccttttataggttttacctactatagtgaaaatttgttg
ttaggtgactctccttcatcctgtacagaaaatgattcagtacaatcaaggaaaaatgag
caatctgtacagattcaaaaaaaattatacttactagaagaacacctcaaaaatgagata
caagccaaagaggacctggaccagaagtgcaaattggttaacactcgactagagaagata
acaaaagaactagaagaagaggttacctcaagaaagaatgtagaatctgcattaagacaa
ttagagagagagaaagctcttcttcaacacaaaaatacagagtaccagcggaaagcagaa
catgaagcagacaaaaaacggaatctagaaaacgatgttaacagcttgaaagatcagctt
gaagatttgaaaaaaagaaatcaaaactctcaaatatctaatgaaaaagtcaatcagctc
cagagacaattggatgaagccaatgctttgctgcgaactgagtctgatactgcgtccagg
ttacggaaaaaccagacagaaagttcaaaacaaattcagcagctggaatctaataatagg
gaactacaagacaaaaattgcacgctagagaatgctaaactgaaacttgaaaaggatttc
atcaatcttcagtcagctctagaatctgaaaggagagatagaacccatggatcagagatc
attaatgatttacaaggtagaatatctggtttggaagaagatattaagaatggtaaaatt
tcattagcaaaaatggagttagagaagaggcaactacaggagagatttacagatttagaa
aaggaaaaaagtaacatggaaatagacatgacatacaaactgaaagttatacagcagagc
ttggaacaggaagaagcagaacataaagctacaaaagcacggttagcagataagaataag
atatatgaatctattgaggaggccaagtctgaagctatgaaagaaatggagaagaaactc
ctagaggaaagaactttaaaacaaaaggtggaaaaccttctgttggaagctgaaaaaaga
tgttcaatgttggactgcgacctcaaacagtcccaacagaaagtcaacgaactcttgaaa
cagaaggacaaactaaatgaagatgtcaggaacttgaccttaaaaatagagcaagaaact
caaaagcgctgcctcacacaaaatgacctgaagatgcaaacacagcaagtcaacacactg
aaaatgtctgaaaaacaaatgaaacaagaaaataatcatcttatggaaatcaaaatgagt
ctggaaaagcaaaatatcgaacttcggaaagaacgacaagatgcagatggacaaatgaaa
gagctccaagatcagctcgaagcagaacaatatttctcaactctctataaaacacaagtt
cgagagcttaaagaagaatgtcaagagaagaccaagctttgcaaagaaatgcagcagaag
agccaggaattacaggatgagagggactccctggctgcacaactggagatcaccttgaca
aaagctgattcagagcagctagcccgttctattgctgaagaacagtactctgatttggaa
aaagagaagatcatgaaagagctggaaattaaagagatgatggctcgacacaaacaagaa
cttgcagaaaaagatgctacaatagcatctctcgaggaggctaataggacactaactagt
gatgtggctaatctggcaaatgagaaagaagaactgaataataaagtcaaggaagtccaa
gagcaaatgtcaaagttgaaagatgaagaaacaaatatatcagttattaaaacgcaattt
gagaagcaactattaaatgagagaacactaaaaactcaggctgtgaataaattggctgag
attatgaatcgaaaagaacctcccaggcgtggtgctgacacagatgtgaggaggaaagag
aaagagaacagaaagctacatatggaacttaaatcagaacgtgaaaagttaactcaacag
atgatcaaatatcaaaaagaactcaatgaaatgcaagctcaaatagctgaagaaagccaa
attcgaattgaactgcaaatgactctggacagtaaagacagtgacattgaacagcttcga
tcacagctccaggccttacacattggtctagatagttccagtataggcagtggaccaggg
gaagctgaggcagatgatgggttcccaggtacagaatcaagattagagggatggctttca
ttgcctgtacgaaacaacactaagaagtttggatgggttaaaaagtatgtgattgtaagc
agcaagaagattcttttctatgatagtgaacaagataaagaacagtctaatccttacatg
gtgttagatatagacaagttgttccatgtccggccagtcacacagacagatgtttataga
gctgattccaaagagattccaaggatattccagatcctgtatgctaatgaaggtgaaagc
aaaaaagaacaagaatttcccgtggaaccagttggggaaaagtcaaactgcatttgccac
aaaggacatgaatttattcccactctttatcatttcccaaccaactgtgaggcctgtatg
aagccactttggcacatgtttaaacctccacctgctcttgagtgtcgccgctgccatatc
aaatgccataaagaccacatggacaaaaaggaggaaatcatagcaccttgtaaagtatac
tatgacatttcatcggcaaagaatctgctgttgttagccaattctacagaggaccagcag
aagtgggtcagtcggttggtaaaaaagatacccaaaaagcccccagcaccagatcctttt
gctcggtcatctcctagaacttctatgaaggtacagcccaaccagtctataagacggcca
agtcgacagcttcctccaagcaaaccaagttctggccctccccttcgaattattcttcat
tga
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