Phascolarctos cinereus (koala): 110210914
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Entry
110210914 CDS
T05867
Name
(RefSeq) receptor tyrosine-protein kinase erbB-3 isoform X1
KO
K05084
receptor tyrosine-protein kinase erbB-3 [EC:
2.7.10.1
]
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw01521
EGFR tyrosine kinase inhibitor resistance
pcw04010
MAPK signaling pathway
pcw04012
ErbB signaling pathway
pcw04020
Calcium signaling pathway
pcw04151
PI3K-Akt signaling pathway
pcw05205
Proteoglycans in cancer
pcw05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
110210914
04012 ErbB signaling pathway
110210914
04020 Calcium signaling pathway
110210914
04151 PI3K-Akt signaling pathway
110210914
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
110210914
05205 Proteoglycans in cancer
110210914
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
110210914
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcw01001
]
110210914
Enzymes [BR:
pcw01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
110210914
Protein kinases [BR:
pcw01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
110210914
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Furin-like
Pkinase
Kinase-like
TM_ErbB1
NtrY_N
Motif
Other DBs
NCBI-GeneID:
110210914
NCBI-ProteinID:
XP_020845660
UniProt:
A0A6P5KJ32
LinkDB
All DBs
Position
Unknown
AA seq
1336 aa
AA seq
DB search
MKGLLELQVLGWLLHLARGSEVGSSQAVCPGTLNGLSVTGDAENQYQTLYKLYDRCEVVM
GNLEIVLTGHSPDLSFLQWIREVTGYVLIAMNEFSTLPLPNLRVVRGAQVYDGKFAIFVM
LNYNTNSSHALRQLRLNQLTEILAGGVYIERNDKLCHMDTIDWRDIVRDPQAEIVVKNNG
KSCPPCHESCGGKCWGPGPGDCQTLTKTICAPQCNGHCFGPNPNQCCHDECAGGCGGPRE
TDCFACRHFNDSGACVSLCPLPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVIDHTS
CVRACPGDKMEVEKNGMKMCEPCGGLCPKACEGTGSGSRFQTVDSSNIDGFVNCTKILGN
LDFLITGLKGDPWHNIPALDPEKLNVFQTVREITGYLNIQSWPPHMHNFSVFSNLTTIGG
RSLYNRGFSLLIMKNVNVTSLGLRSLKEVSAGRIYISANKQLCYHHSLNWTRLLRGPKEG
RLDIKHNRPKKECVAEGRVCDPLCSSGGCWGPGPGQCLSCRNYSRGGVCVTQCNFLNGEP
REFAHEDECFSCHPECQPLEGNVTCYGSGSDACAQCAHFRDGPHCVSSCPHGLVGAKGPI
YKYPDAHRECLPCHENCTQGCNGPELHDCLGQPQAISSKTHVAVGLAVVAGLIVITLVLL
LTLLYLRGRKIQNKRAMRRYLERGESLEPLDPGEKANKVLARIFKETELRKLKVLGSGVF
GTVHKGIWIPEGESIKIPVCIKVIEDRSGRQSFQSVTDHMLAIGSLDHTHIVRLLGLCPG
SSLQLVTQFLPLGSVLDHVRQHRETLGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNV
LLKSPSQVQVADFGVADLLPPDDKQLLHSEAKTPIKWMALESIHFGKYTHQSDVWSYGVT
IWELMTFGDIPYKGLRLAEVPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKE
LANEFTRMARDPPRYLVIKRDSSPGLPPGAEPPALTDKDLEEVETLEPELELELEEEELA
NTLGSAPSLPVGTLSRPRGSQNFLSPSSGYMPMNQSNLGGTRQGSVIRGSSEQCPCPTSL
LQSPRGRLASESSEGRGTSSEAELQEAESVCGSRSPRPRGDSAYHSQRHSLLTPLTPLTP
PGLEEEDVNGYVMPDAHTKGIPSSRDGTLSSSVGLSSILGTEEEEDEDEEYEYMNRRRKQ
SLPRPPRPGSLEELGYEYMDVGSDLSASLGSTHSCPLHPVPIMPATGTTPDEDYEYMNRR
HGGGTAGGDYAAMGGCPAAEQGYEEMGSFQGPGHHAPYIHDAHLKPLRSLEATHSAFDNP
DYWHSRLFSKASAQGT
NT seq
4011 nt
NT seq
+upstream
nt +downstream
nt
atgaaggggttactggagctgcaggtattgggctggctcctccacctggccaggggctcg
gaggtgggcagctcgcaggcagtgtgcccagggaccctcaatggactgagtgtaaccggt
gatgcggaaaaccagtatcagacactttacaaactatatgatcggtgtgaggttgtgatg
ggaaacctggaaattgtgcttacagggcatagccctgatctctccttcctgcagtggatc
cgggaggtaacaggatatgtcctaatcgccatgaatgagttctctactctgccactcccc
aaccttcgtgtggtaaggggggcccaggtctatgacgggaagtttgccatctttgtcatg
ctcaactataataccaactccagccatgccctacgccagctccgcctcaatcagctcaca
gagatcttggctgggggtgtttacattgaaaggaatgataaactttgccacatggacaca
attgactggagagacatcgtcagggacccacaggctgagattgtggtcaagaacaatggc
aaaagctgtcccccttgtcatgagtcctgtggggggaaatgctggggtcctggaccagga
gactgccaaacactgacaaagacaatctgtgccccccaatgcaacggccactgctttggc
cccaatcccaaccagtgctgccatgatgagtgcgcaggtggctgtggaggtccccgagag
acagactgctttgcatgccgacacttcaatgacagtggagcctgtgtgtctctgtgccca
ctgccccttgtctacaacaaactcaccttccaactagagcccaatcctcacaccaagtac
cagtatggaggggtctgtgtggccagctgtccccataactttgtgatagatcacacctcc
tgtgtcagggcctgtcctggggacaagatggaggtagaaaagaatgggatgaagatgtgt
gagccctgtggagggctgtgtccaaaagcctgtgaagggacaggctcaggtagccgattt
cagactgtggactctagcaacatcgatgggtttgtgaactgtaccaagatcttgggaaat
ctggacttccttatcactggcctcaaaggagacccctggcacaacatacctgccctggat
cctgagaaactcaacgtcttccagacagttcgggagattacaggttacctgaacatccag
tcttggcctccccacatgcacaactttagtgtcttctccaacctgacaaccataggtggc
cgaagtctctacaatcgaggtttctcactgctgatcatgaaaaacgtgaacgtgacatcg
ttgggccttcggtccctgaaagaagtcagtgctgggcgtatttatatcagtgccaacaag
cagctctgctaccaccactctctgaactggaccaggctgcttcggggaccaaaggaaggg
aggttggatatcaagcacaatcgccccaaaaaggaatgtgtggcagagggtcgagtgtgt
gacccactgtgctcatctgggggttgctggggccctggtcctggccagtgcttatcctgt
cgaaactacagtcgagggggtgtctgtgtgacccaatgcaacttccttaatggagaaccc
cgagagtttgctcatgaggatgaatgcttctcctgccatcctgagtgccagcctctggag
ggcaatgtcacttgctatggctcgggctcagatgcttgtgctcagtgtgcccacttccgg
gatggaccacattgtgtgagcagctgcccccacggactcgtgggtgccaaaggacccatc
tacaagtacccagatgctcatcgagagtgtctgccttgccatgagaactgcactcagggg
tgtaatggaccagaactccatgactgtttgggacaaccacaggccataagcagtaagacc
catgtggctgtgggcctagctgtggtggcaggcttgatcgtgatcacgttggtcttgcta
cttaccttgctctacttgcgagggcggaagatccagaataagagagcaatgaggcgctac
ttggagcggggtgagagcctggaacctctagaccctggtgaaaaggccaacaaggtcttg
gcccgaattttcaaggagacagagctgaggaaactcaaagtgcttggttcaggtgtcttt
ggaactgtgcacaagggcatatggatcccagagggcgagtccatcaagatcccagtctgc
attaaagtcattgaagacaggagcggacggcagagtttccagtcggtgactgatcacatg
ttggccattggcagcttagatcatacccatatcgttcggctactagggctatgcccgggg
tcatctctgcagctggtcacccaatttctgccattgggatcagtgctagaccacgtacga
caacatcgggagactctaggaccgcagttactgctcaactggggtgtgcagattgccaag
ggcatgtactacctggaggaacatggcatggtgcacagaaatctggctgctcgaaatgtg
ctgctgaagtccccaagtcaggtgcaggttgctgactttggggtggctgacctgctgcca
cctgatgataaacaacttttgcacagtgaggctaagacaccaatcaagtggatggccctg
gagagtatccattttggaaaatacacacaccagagtgacgtctggagttatggtgtgaca
atatgggaactgatgacatttggagacataccctataaagggcttcgactggctgaagtg
cctgacctgctggagaagggagagcgtctagcacagccacagatctgtactattgatgtc
tacatggtcatggttaaatgctggatgattgatgaaaacatacgaccgacatttaaagaa
ttggctaacgaattcacccgaatggctcgggatccaccacgatatttggtcatcaagagg
gacagtagtcctgggctgcctcctggtgcagagccacctgctctgactgacaaagacctg
gaggaggtagagacactggaaccggagctggagctggagctagaggaggaagaactggca
aacacactaggctctgcccccagcctgcccgttggtacgctgtccagaccacgtgggagt
cagaactttctgagtccttcatctggatacatgccaatgaaccagagcaacctaggaggc
accagacaggggtcagtgattcgtgggagtagtgagcagtgcccctgcccaacctcttta
ctccagagcccacgaggccgacttgcatcagaatcttcagaaggccgggggacaagctcc
gaggctgagctgcaagaggcagaatctgtgtgtggaagccggagccctcggcctcgaggg
gacagtgcctaccattcccaacgccacagcctactcactcccctcacccccctcacccca
ccagggctagaggaagaggatgtcaacggttatgttatgcctgatgcacataccaaaggt
attccttcttcccgggatggtacactgtcatcatctgtgggcctcagttccattctgggc
accgaagaagaagaggatgaggatgaagagtatgaatacatgaatcggagaagaaagcag
agtctgccaagacctccaaggccaggatctctggaagagttgggctatgaatatatggat
gtgggatcagacctcagtgcctccttaggcagcacccacagctgtccactccatcctgta
cccatcatgcctgctacaggaactactcctgatgaggattatgagtatatgaatcgtcga
catggtggaggaactgctgggggtgattatgcagccatggggggttgcccagcagctgag
caagggtatgaagaaatgggatcgtttcaaggccctgggcaccatgccccctacatccat
gatgcccacctcaagccccttcgaagcctagaggccactcactctgcctttgacaaccct
gactactggcatagccggcttttctccaaggccagtgctcaggggacataa
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