Phascolarctos cinereus (koala): 110216682
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Entry
110216682 CDS
T05867
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw04120
Ubiquitin mediated proteolysis
pcw04144
Endocytosis
pcw04330
Notch signaling pathway
pcw04668
TNF signaling pathway
pcw04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
110216682 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
110216682 (ITCH)
04668 TNF signaling pathway
110216682 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
110216682 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
110216682 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pcw04131
]
110216682 (ITCH)
04121 Ubiquitin system [BR:
pcw04121
]
110216682 (ITCH)
Enzymes [BR:
pcw01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
110216682 (ITCH)
Membrane trafficking [BR:
pcw04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
110216682 (ITCH)
Ubiquitin system [BR:
pcw04121
]
Ubiquitin ligases (E3)
HECT type E3
110216682 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
PQQ_2
Motif
Other DBs
NCBI-GeneID:
110216682
NCBI-ProteinID:
XP_020854208
UniProt:
A0A6P5L848
LinkDB
All DBs
Position
Unknown
AA seq
868 aa
AA seq
DB search
MSGSSSRSGSVGGLTMKSQLQIIVISAKLKENKKNWFGPSPYVEVSVDGQSKKTEKCSNT
NSPKWKQPLTVIVTPVSKLNFRVWSHQTLKSDVLLGSAALDIHETLKSNNMKLDEVIVTL
QLVGDKEPTEIIGDLSVCLDGLQVDPEILTNGYATCSEGSSQSDDSRTRNDTRSNTDGPE
NAEEAGPSENRKVNGNNSPSLTNGGFKPPRPPRPSRPPPPTPRRPASVNASPSAPSEAPV
SSTESSPSTNMSVTPEGAAAPATAALTTPPASRQVQPANSASQQLSTVNQGPLPPGWEQR
VDQHGRVYYVDHVEKRTSWDRPEPLPPGWERRVDNMGRVYYVDHFTRTTTWQRPTLESVR
NYEQWQLQRSQLQGAMQQFNQRFIYGNQDLFTSSQNKEFDPLGPLPPGWEKRTDNNGRVY
FVNHNTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGVPYFVDHNRRTTTYIDPRTGKSA
LDNGPQIAYVRDFKAKVHYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFNPQDLRR
RLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHL
KYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENN
IEECGLEMYFSVDKEILGEIKSHELKPNGSNILVTEENKEEYIRMVAEWRLSRGVEEQTQ
AFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQF
VKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRL
DLPPYKSYEQLKEKLLFAIEETEGFGQE
NT seq
2607 nt
NT seq
+upstream
nt +downstream
nt
atgtctggcagtagttcacggtcagggtctgtggggggattgaccatgaaatcacaactt
cagatcattgtcatctcagcaaagcttaaagaaaataaaaagaactggtttggaccaagt
ccttatgtggaagtctcagtagatggacagtcaaagaagacagaaaaatgcagcaatacc
aacagtcccaagtggaagcagcctcttactgtaattgtcacacctgtcagcaaattaaat
tttcgtgtatggagtcaccagacattaaaatccgatgttttactgggaagtgctgctcta
gatattcatgaaacgttaaagtcaaataatatgaaacttgatgaagtaattgtgacatta
caactcgtgggtgacaaggagccaacagaaatcataggagacttgtcagtttgccttgat
ggactacaagtagatcccgagattctaacgaatggctatgccacatgttcagaaggtagt
tcacagagtgatgattccagaaccaggaatgatacaagatcaaatacagatggacctgaa
aatgctgaggaagcaggacccagtgaaaataggaaggtcaatggcaataactctccatca
ctcacaaatggaggctttaaacctcctaggcctccaagaccttcacggccacctcctccc
actcctcgtagaccagcatctgtcaatgcttctccatctgcaccttctgaggctcctgtg
tctagtacagagtcgtcaccatcaacaaacatgagtgtaactcctgagggagcagcagca
cctgccaccgcggctttaacgacacccccagcttccagacaagtgcagccagcgaattct
gcttctcaacagctcagtacagtcaatcaaggtcctcttccaccgggttgggagcagaga
gtggaccagcatggacgagtctactatgtagatcatgttgaaaaaagaacatcgtgggat
agaccagaacctcttcctcctggctgggaacgtcgagttgacaacatgggacgtgtttat
tatgttgaccacttcacaagaactaccacctggcagcggccaactttggagtcagttaga
aactatgagcagtggcagctacaacgaagtcaactccaaggagcaatgcagcagtttaac
cagagattcatttatgggaatcaagatttgtttacttcatctcagaataaagaatttgat
cctcttggacctctgccaccaggatgggagaagagaacagacaacaatggcagggtgtat
tttgtcaatcacaacacacgcattacacagtgggaagatcccagaagtcaaggtcagtta
aatgagaagcctttaccggaaggctgggaaatgagatttactgtggatggagttccatat
tttgtggatcacaataggagaacgacaacctatatagatccccgaacgggaaaatctgct
ctagataatggaccccaaatagcctatgttagggatttcaaggcaaaagttcactatttc
cgtttctggtgtcagcaattggctatgccacagcacatcaagattacagtgacaagaaaa
actttgtttgaagattcatttcagcagataatgagtttcaatccccaggatcttcgaaga
cgtttgtgggtgatttttccaggagaagaaggtttagattatggaggtgtggcaagagaa
tggttctttcttttgtcacatgaagtgctgaacccaatgtattgcctgtttgaatatgca
gggaaggataattactgcttgcaaataaacccagcttcttatatcaatccagaccatctg
aaatactttcgttttattggcaggtttattgccatggcattattccatggaaaattcata
gatacaggcttttctttgccattctataaacgtatcttgaataaacctgttggactcaag
gacctagaatctattgatccagaattttacaattctctcatctgggttaaagaaaacaat
atcgaagaatgtggtttagagatgtacttctcagttgataaggaaattcttggtgaaatt
aagagtcatgaactgaaacccaatggcagtaatattctagtaacagaagaaaataaagaa
gaatacattagaatggtagctgaatggagattatctcggggtgttgaagagcagacacaa
gctttcttcgaaggcttcaatgaaatcctcccccagcagtacctgcagtactttgatgct
aaggaactagaggtacttttgtgtggaatgcaagagattgatttaaatgactggcagaga
catgccatctaccgacattatactaggacaagcaaacaaatcatgtggttttggcagttt
gtgaaagaaattgacaatgagaagagaatgagactgttgcagtttgtcactggcacttgc
aggttgccggttgggggattcgctgacctcatggggagcaatggaccacaaaagttttgc
attgaaaaagttgggaaagaaaattggttacctagaagtcatacctgtttcaaccgcttg
gatctaccaccctacaagagctatgaacaactgaaggaaaaactgttatttgctattgag
gaaacagaaggatttggacaagagtaa
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