KEGG   PATHWAY: pda00945
Entry
pda00945                    Pathway                                
Name
Stilbenoid, diarylheptanoid and gingerol biosynthesis - Phoenix dactylifera (date palm)
Description
Stilbenoids are a group of phenolic compounds, biosynthetically interrelated through their common origin from a C6-C2-C6 intermediate, such as resveratol found in grapes. Stilbenoids can also exist as glycosides (e.g., piceid). Combretastatins are potentially useful stilbenoid natural products with known antitumor activity. Diarylheptanoid is a compound group having phenyl rings at 1,7 positions of n-heptane (C6-C7-C6), such as curcumin found in the ginger family. [6]-Gingerol is a major active component of ginger and has diverse pharmacologic effects.
Class
Metabolism; Biosynthesis of other secondary metabolites
Pathway map
pda00945  Stilbenoid, diarylheptanoid and gingerol biosynthesis
pda00945

Organism
Phoenix dactylifera (date palm) [GN:pda]
Gene
103697376  [KO:K13065] [EC:2.3.1.133]
103697378  [KO:K13065] [EC:2.3.1.133]
103699039  [KO:K13065] [EC:2.3.1.133]
103701551  [KO:K00588] [EC:2.1.1.104]
103701552  [KO:K00588] [EC:2.1.1.104]
103702142  [KO:K00487] [EC:1.14.14.91]
103702256  [KO:K00487] [EC:1.14.14.91]
103705056  [KO:K09754] [EC:1.14.14.96]
103706246  [KO:K00487] [EC:1.14.14.91]
103706282  [KO:K09754] [EC:1.14.14.96]
103707445  [KO:K13065] [EC:2.3.1.133]
103707448  [KO:K13065] [EC:2.3.1.133]
103708914  [KO:K00487] [EC:1.14.14.91]
103710057  [KO:K00588] [EC:2.1.1.104]
103710206  [KO:K13065] [EC:2.3.1.133]
103712513  [KO:K13065] [EC:2.3.1.133]
103713131  [KO:K00487] [EC:1.14.14.91]
103713767  [KO:K00588] [EC:2.1.1.104]
103716242  [KO:K13065] [EC:2.3.1.133]
103722165  [KO:K00487] [EC:1.14.14.91]
103722553  [KO:K00588] [EC:2.1.1.104]
120107377  [KO:K00588] [EC:2.1.1.104]
120107378  [KO:K00588] [EC:2.1.1.104]
120110174  [KO:K00487] [EC:1.14.14.91]
120113086  [KO:K00588] [EC:2.1.1.104]
Compound
C00223  p-Coumaroyl-CoA
C00323  Caffeoyl-CoA
C00406  Feruloyl-CoA
C00540  Cinnamoyl-CoA
C00852  Chlorogenate
C01745  Pinosylvin
C02947  4-Coumaroylshikimate
C03582  Resveratrol
C05901  Piceatannol
C10287  Pterostilbene
C10434  5-O-Caffeoylshikimic acid
C10443  Curcumin
C10462  [6]-Gingerol
C12208  p-Coumaroyl quinic acid
C17740  p-Coumaroyl-diketide-CoA
C17741  Feruloyl-diketide-CoA
C17742  Demethoxycurcumin
C17743  Bisdemethoxycurcumin
C17744  1-(4-Hydroxyphenyl)-1-decene-3,5-dione
C17745  1-(3,4-Dihydroxyphenyl)-1-decene-3,5-dione
C17746  1-Dehydro-[6]-gingerdione
C17747  5-Hydroxy-1-(4-hydroxyphenyl)-3-decanone
C17748  1-(3,4-Dihydroxyphenyl)-5-hydroxy-3-decanone
C17749  Curcumin monoglucoside
C17750  Curcumin diglucoside
C22988  4'-O-Methyl-trans-resveratrol
Reference
  Authors
Katsuyama Y, Kita T, Funa N, Horinouchi S
  Title
Curcuminoid biosynthesis by two type III polyketide synthases in the herb Curcuma longa.
  Journal
J Biol Chem 284:11160-70 (2009)
DOI:10.1074/jbc.M900070200
Reference
  Authors
Ramirez-Ahumada Mdel C, Timmermann BN, Gang DR
  Title
Biosynthesis of curcuminoids and gingerols in turmeric (Curcuma longa) and ginger (Zingiber officinale): identification of curcuminoid synthase and hydroxycinnamoyl-CoA thioesterases.
  Journal
Phytochemistry 67:2017-29 (2006)
DOI:10.1016/j.phytochem.2006.06.028
Reference
  Authors
Masada S, Terasaka K, Mizukami H
  Title
A single amino acid in the PSPG-box plays an important role in the catalytic function of CaUGT2 (Curcumin glucosyltransferase), a Group D Family 1 glucosyltransferase from Catharanthus roseus.
  Journal
FEBS Lett 581:2605-10 (2007)
DOI:10.1016/j.febslet.2007.05.002
Related
pathway
pda00940  Phenylpropanoid biosynthesis
KO pathway
ko00945   

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