KEGG   PATHWAY: pdic00531
Entry
pdic00531                   Pathway                                
Name
Glycosaminoglycan degradation - Phyllostomus discolor (pale spear-nosed bat)
Class
Metabolism; Glycan biosynthesis and metabolism
Pathway map
pdic00531  Glycosaminoglycan degradation
pdic00531

Module
pdic_M00076  Dermatan sulfate degradation [PATH:pdic00531]
pdic_M00077  Chondroitin sulfate degradation [PATH:pdic00531]
pdic_M00078  Heparan sulfate degradation [PATH:pdic00531]
pdic_M00079  Keratan sulfate degradation [PATH:pdic00531]
Other DBs
GO: 0006027
Organism
Phyllostomus discolor (pale spear-nosed bat) [GN:pdic]
Gene
114501414  HYAL2; LOW QUALITY PROTEIN: hyaluronidase-2 [KO:K01197] [EC:3.2.1.35]
114507228  SPAM1; hyaluronidase PH-20 [KO:K01197] [EC:3.2.1.35]
114507240  HYAL4; hyaluronidase-4 [KO:K01197] [EC:3.2.1.35]
114501418  hyaluronidase-3 isoform X1 [KO:K01197] [EC:3.2.1.35]
114505797  GUSB; beta-glucuronidase isoform X1 [KO:K01195] [EC:3.2.1.31]
114505161  IDS; iduronate 2-sulfatase isoform X1 [KO:K01136] [EC:3.1.6.13]
114489977  IDUA; alpha-L-iduronidase isoform X2 [KO:K01217] [EC:3.2.1.76]
114509932  ARSB; arylsulfatase B isoform X1 [KO:K01135] [EC:3.1.6.12]
114492003  HPSE; heparanase isoform X1 [KO:K07964] [EC:3.2.1.166]
114497813  HPSE2; inactive heparanase-2 isoform X1 [KO:K07965] [EC:3.2.1.-]
114503187  SGSH; N-sulphoglucosamine sulphohydrolase isoform X1 [KO:K01565] [EC:3.10.1.1]
114508545  HGSNAT; heparan-alpha-glucosaminide N-acetyltransferase [KO:K10532] [EC:2.3.1.78]
114502490  NAGLU; alpha-N-acetylglucosaminidase [KO:K01205] [EC:3.2.1.50]
114488241  GALNS; N-acetylgalactosamine-6-sulfatase isoform X1 [KO:K01132] [EC:3.1.6.4]
114501877  GLB1; beta-galactosidase isoform X2 [KO:K12309] [EC:3.2.1.23]
114513208  GNS; N-acetylglucosamine-6-sulfatase [KO:K01137] [EC:3.1.6.14]
114490166  HEXB; beta-hexosaminidase subunit beta [KO:K12373] [EC:3.2.1.52]
114492663  HEXA; LOW QUALITY PROTEIN: beta-hexosaminidase subunit alpha [KO:K12373] [EC:3.2.1.52]
Compound
C00426  Dermatan sulfate
C00573  Keratan sulfate
C00634  Chondroitin 4-sulfate
C00925  Heparan sulfate
G00526   
G00711   
G00872  DWA-2
G01391   
G01945   
G01977   
G02632   
G09660   
G10008   
G10505  Hyaluronic acid
G12336   
G13034   
G13035   
G13036   
G13037   
G13038   
G13039   
G13040   
G13041   
G13042   
G13043   
G13073   
G13074   
Reference
PMID:27570
  Authors
Greiling H, Stuhlsatz HW, Cantz M, Gehler J
  Title
Increased urinary excretion of keratan sulfate in fucosidosis.
  Journal
J Clin Chem Clin Biochem 16:329-34 (1978)
DOI:10.1515/cclm.1978.16.6.329
Reference
PMID:3161730
  Authors
Fuchs W, Beck M, Kresse H
  Title
Intralysosomal formation and metabolic fate of N-acetylglucosamine 6-sulfate from keratan sulfate.
  Journal
Eur J Biochem 151:551-6 (1985)
DOI:10.1111/j.1432-1033.1985.tb09138.x
Related
pathway
pdic00532  Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
pdic00533  Glycosaminoglycan biosynthesis - keratan sulfate
pdic00534  Glycosaminoglycan biosynthesis - heparan sulfate / heparin
KO pathway
ko00531   
LinkDB

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