KEGG   Phyllostomus discolor (pale spear-nosed bat): 114495334
Entry
114495334         CDS       T07739                                 
Symbol
TNF
Name
(RefSeq) tumor necrosis factor isoform X1
  KO
K03156  tumor necrosis factor superfamily, member 2
Organism
pdic  Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic01523  Antifolate resistance
pdic04010  MAPK signaling pathway
pdic04060  Cytokine-cytokine receptor interaction
pdic04061  Viral protein interaction with cytokine and cytokine receptor
pdic04064  NF-kappa B signaling pathway
pdic04071  Sphingolipid signaling pathway
pdic04150  mTOR signaling pathway
pdic04210  Apoptosis
pdic04217  Necroptosis
pdic04350  TGF-beta signaling pathway
pdic04380  Osteoclast differentiation
pdic04612  Antigen processing and presentation
pdic04620  Toll-like receptor signaling pathway
pdic04621  NOD-like receptor signaling pathway
pdic04622  RIG-I-like receptor signaling pathway
pdic04625  C-type lectin receptor signaling pathway
pdic04640  Hematopoietic cell lineage
pdic04650  Natural killer cell mediated cytotoxicity
pdic04657  IL-17 signaling pathway
pdic04660  T cell receptor signaling pathway
pdic04664  Fc epsilon RI signaling pathway
pdic04668  TNF signaling pathway
pdic04920  Adipocytokine signaling pathway
pdic04930  Type II diabetes mellitus
pdic04931  Insulin resistance
pdic04932  Non-alcoholic fatty liver disease
pdic04933  AGE-RAGE signaling pathway in diabetic complications
pdic04936  Alcoholic liver disease
pdic04940  Type I diabetes mellitus
pdic05010  Alzheimer disease
pdic05014  Amyotrophic lateral sclerosis
pdic05020  Prion disease
pdic05022  Pathways of neurodegeneration - multiple diseases
pdic05132  Salmonella infection
pdic05133  Pertussis
pdic05134  Legionellosis
pdic05135  Yersinia infection
pdic05140  Leishmaniasis
pdic05142  Chagas disease
pdic05143  African trypanosomiasis
pdic05144  Malaria
pdic05145  Toxoplasmosis
pdic05146  Amoebiasis
pdic05152  Tuberculosis
pdic05160  Hepatitis C
pdic05161  Hepatitis B
pdic05163  Human cytomegalovirus infection
pdic05164  Influenza A
pdic05165  Human papillomavirus infection
pdic05166  Human T-cell leukemia virus 1 infection
pdic05168  Herpes simplex virus 1 infection
pdic05169  Epstein-Barr virus infection
pdic05170  Human immunodeficiency virus 1 infection
pdic05171  Coronavirus disease - COVID-19
pdic05205  Proteoglycans in cancer
pdic05310  Asthma
pdic05321  Inflammatory bowel disease
pdic05322  Systemic lupus erythematosus
pdic05323  Rheumatoid arthritis
pdic05330  Allograft rejection
pdic05332  Graft-versus-host disease
pdic05410  Hypertrophic cardiomyopathy
pdic05414  Dilated cardiomyopathy
pdic05417  Lipid and atherosclerosis
pdic05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pdic00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    114495334 (TNF)
   04350 TGF-beta signaling pathway
    114495334 (TNF)
   04064 NF-kappa B signaling pathway
    114495334 (TNF)
   04668 TNF signaling pathway
    114495334 (TNF)
   04071 Sphingolipid signaling pathway
    114495334 (TNF)
   04150 mTOR signaling pathway
    114495334 (TNF)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    114495334 (TNF)
   04061 Viral protein interaction with cytokine and cytokine receptor
    114495334 (TNF)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    114495334 (TNF)
   04217 Necroptosis
    114495334 (TNF)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    114495334 (TNF)
   04620 Toll-like receptor signaling pathway
    114495334 (TNF)
   04621 NOD-like receptor signaling pathway
    114495334 (TNF)
   04622 RIG-I-like receptor signaling pathway
    114495334 (TNF)
   04625 C-type lectin receptor signaling pathway
    114495334 (TNF)
   04650 Natural killer cell mediated cytotoxicity
    114495334 (TNF)
   04612 Antigen processing and presentation
    114495334 (TNF)
   04660 T cell receptor signaling pathway
    114495334 (TNF)
   04657 IL-17 signaling pathway
    114495334 (TNF)
   04664 Fc epsilon RI signaling pathway
    114495334 (TNF)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    114495334 (TNF)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    114495334 (TNF)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    114495334 (TNF)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    114495334 (TNF)
   05170 Human immunodeficiency virus 1 infection
    114495334 (TNF)
   05161 Hepatitis B
    114495334 (TNF)
   05160 Hepatitis C
    114495334 (TNF)
   05171 Coronavirus disease - COVID-19
    114495334 (TNF)
   05164 Influenza A
    114495334 (TNF)
   05168 Herpes simplex virus 1 infection
    114495334 (TNF)
   05163 Human cytomegalovirus infection
    114495334 (TNF)
   05169 Epstein-Barr virus infection
    114495334 (TNF)
   05165 Human papillomavirus infection
    114495334 (TNF)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    114495334 (TNF)
   05135 Yersinia infection
    114495334 (TNF)
   05133 Pertussis
    114495334 (TNF)
   05134 Legionellosis
    114495334 (TNF)
   05152 Tuberculosis
    114495334 (TNF)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    114495334 (TNF)
   05144 Malaria
    114495334 (TNF)
   05145 Toxoplasmosis
    114495334 (TNF)
   05140 Leishmaniasis
    114495334 (TNF)
   05142 Chagas disease
    114495334 (TNF)
   05143 African trypanosomiasis
    114495334 (TNF)
  09163 Immune disease
   05310 Asthma
    114495334 (TNF)
   05322 Systemic lupus erythematosus
    114495334 (TNF)
   05323 Rheumatoid arthritis
    114495334 (TNF)
   05321 Inflammatory bowel disease
    114495334 (TNF)
   05330 Allograft rejection
    114495334 (TNF)
   05332 Graft-versus-host disease
    114495334 (TNF)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    114495334 (TNF)
   05014 Amyotrophic lateral sclerosis
    114495334 (TNF)
   05020 Prion disease
    114495334 (TNF)
   05022 Pathways of neurodegeneration - multiple diseases
    114495334 (TNF)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    114495334 (TNF)
   05418 Fluid shear stress and atherosclerosis
    114495334 (TNF)
   05410 Hypertrophic cardiomyopathy
    114495334 (TNF)
   05414 Dilated cardiomyopathy
    114495334 (TNF)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    114495334 (TNF)
   04940 Type I diabetes mellitus
    114495334 (TNF)
   04936 Alcoholic liver disease
    114495334 (TNF)
   04932 Non-alcoholic fatty liver disease
    114495334 (TNF)
   04931 Insulin resistance
    114495334 (TNF)
   04933 AGE-RAGE signaling pathway in diabetic complications
    114495334 (TNF)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    114495334 (TNF)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:pdic04052]
    114495334 (TNF)
   00536 Glycosaminoglycan binding proteins [BR:pdic00536]
    114495334 (TNF)
Cytokines and neuropeptides [BR:pdic04052]
 Cytokines
  Tumor necrosis fators
   114495334 (TNF)
Glycosaminoglycan binding proteins [BR:pdic00536]
 Heparan sulfate / Heparin
  Cytokines
   114495334 (TNF)
SSDB
Motif
Pfam: TNF
Other DBs
NCBI-GeneID: 114495334
NCBI-ProteinID: XP_028366388
UniProt: A0A6J2LJY4
LinkDB
Position
4:104407235..104409853
AA seq 230 aa
MSTESMIRDVELAEKVLPKKAGGHQGSRRCLCLSLFSFFLVAGATTLFCLLHFGVIGPQR
EEQFLIGPSLARTLGLSSRTPSDKPVAHVVANQQTVGQLQWKNQVANALLANGVQLRNNQ
LVVPLDGLYLIYSQVLFKGQGCPPTHLLLTHTISRYSASYARKVNLLSAIKSPCQRETPE
GTDAKPWYEPIYLGGVFQLEKDDQLSAEVNLPDYLDFAEFGQVYFGLIAL
NT seq 693 nt   +upstreamnt  +downstreamnt
atgagcactgaaagcatgatccgggacgtggagctggctgagaaggtgctccccaagaag
gcagggggtcaccagggctccagacggtgcttgtgcctcagcctcttctccttcttcctc
gtggcaggagccactacactcttctgtctgttgcacttcggtgtgattggcccccagagg
gaagagcagttcctaattggcccctcactggcccggacccttggattatcttctcgaacc
ccaagtgacaagcctgttgcccatgttgtagcaaatcagcaaactgtggggcagctgcag
tggaagaatcaggttgccaatgctctcctggccaatggtgtgcaactgagaaacaaccag
ctggttgtgccattggatgggctgtacctcatctactcccaggtcctcttcaagggccaa
ggctgccctcccacccatttgctcctcacccacaccatcagccgctattccgcctcctac
gcccgaaaggtcaacctcctctccgccatcaagagcccttgccaaagggagaccccagaa
gggactgacgccaagccctggtatgaacccatctacctgggaggggtcttccagctggag
aaagatgatcaactcagcgccgaggtcaacctgcctgactatctcgattttgccgaattt
gggcaggtctactttgggctcattgccctgtga

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