KEGG   Phyllostomus discolor (pale spear-nosed bat): 114497989
Entry
114497989         CDS       T07739                                 
Symbol
DHFR
Name
(RefSeq) dihydrofolate reductase isoform X1
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
pdic  Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic00670  One carbon pool by folate
pdic00790  Folate biosynthesis
pdic01100  Metabolic pathways
pdic01240  Biosynthesis of cofactors
pdic01523  Antifolate resistance
pdic04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:pdic00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    114497989 (DHFR)
   00670 One carbon pool by folate
    114497989 (DHFR)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    114497989 (DHFR)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    114497989 (DHFR)
Enzymes [BR:pdic01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     114497989 (DHFR)
SSDB
Motif
Pfam: DHFR_1 YidX_N
Other DBs
NCBI-GeneID: 114497989
NCBI-ProteinID: XP_028369816
UniProt: A0A6J2LR40
LinkDB
Position
3:complement(50148300..50167456)
AA seq 187 aa
MVRCLNCIVAVSQNMGIGKNGDLPWPRIRNELKYFQRMTTTTSAEGKQNLVIMGRKTWFS
IPEKNRPLQDRINVVLSRELKELPKGAHFLARSLDDALNLIEEPELTNKVDMVWIIGGSS
VYKEAMNRSGHVRLFVTRIMEEFESDTFLPEIDLERYKLLPEYPGVFSDVQEEKGIKFKF
EVYERND
NT seq 564 nt   +upstreamnt  +downstreamnt
atggttcgttgcctaaactgcatcgtcgctgtgtcccagaacatgggcattgggaagaac
ggagacctaccttggcctcggatcaggaatgaactcaaatatttccaaagaatgaccaca
accacttcagcagaaggtaaacagaatttggtgattatgggtaggaagacctggttctcc
attcctgagaagaatcgacctttacaggacaggattaatgtagtcctcagcagagaactc
aaggaacttccaaaaggagctcattttcttgccagaagtctggatgatgccttaaacctt
attgaggaaccagaattaacaaataaagtggacatggtttggataataggaggcagttct
gtgtataaggaagccatgaacaggtcaggccatgttagactgtttgtgacgaggatcatg
gaggaatttgaaagtgacacatttttgccagaaattgatttggagagatacaaacttctc
ccagagtacccaggtgttttttctgatgtccaggaggagaaaggcattaaattcaaattt
gaagtatatgaaaggaatgattaa

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