Phyllostomus discolor (pale spear-nosed bat): 114508468
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Entry
114508468 CDS
T07739
Symbol
IRS2
Name
(RefSeq) insulin receptor substrate 2 isoform X2
KO
K07187
insulin receptor substrate 2
Organism
pdic
Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic04022
cGMP-PKG signaling pathway
pdic04068
FoxO signaling pathway
pdic04081
Hormone signaling
pdic04140
Autophagy - animal
pdic04152
AMPK signaling pathway
pdic04211
Longevity regulating pathway
pdic04213
Longevity regulating pathway - multiple species
pdic04910
Insulin signaling pathway
pdic04920
Adipocytokine signaling pathway
pdic04923
Regulation of lipolysis in adipocytes
pdic04930
Type II diabetes mellitus
pdic04931
Insulin resistance
pdic04932
Non-alcoholic fatty liver disease
pdic04935
Growth hormone synthesis, secretion and action
pdic05010
Alzheimer disease
pdic05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
pdic00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
114508468 (IRS2)
04022 cGMP-PKG signaling pathway
114508468 (IRS2)
04152 AMPK signaling pathway
114508468 (IRS2)
09133 Signaling molecules and interaction
04081 Hormone signaling
114508468 (IRS2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
114508468 (IRS2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
114508468 (IRS2)
04923 Regulation of lipolysis in adipocytes
114508468 (IRS2)
04920 Adipocytokine signaling pathway
114508468 (IRS2)
04935 Growth hormone synthesis, secretion and action
114508468 (IRS2)
09149 Aging
04211 Longevity regulating pathway
114508468 (IRS2)
04213 Longevity regulating pathway - multiple species
114508468 (IRS2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
114508468 (IRS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
114508468 (IRS2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
114508468 (IRS2)
04932 Non-alcoholic fatty liver disease
114508468 (IRS2)
04931 Insulin resistance
114508468 (IRS2)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
IRS
PH
PH_11
MEKK4_N
Mcp5_PH
Motif
Other DBs
NCBI-GeneID:
114508468
NCBI-ProteinID:
XP_028382150
UniProt:
A0A6J2MWE6
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All DBs
Position
11:complement(64197213..64226666)
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AA seq
1335 aa
AA seq
DB search
MASPPLHGPPGPAGSDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGASGEEA
TAGGGPAPQPPRLEYYENEKKWRSKAGAPKRVISLDCCLNINKRADAKHKYLIALYTKDE
YFAVAAENEQEQEGWYRALTDLVSEGRAGAGDSTLSSITTGSCSASLPGALGGSAGADES
YGLVAPATSVYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQLM
NIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFRPR
SKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPATKCSSCRVRT
ASEGDGGTAAGTGAAGGRPVSVAGSPLSPGPVRVPLSRSHTLSGGCGSRVSKVTLPPAGG
ALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPLPPGPHTHLQHPLHHHTSQRPSS
GSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPAKDGSGSELYGYMT
MDRPLSHCGRPYRRVSGDGAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRAT
FSGSSGRLCPTCPTSSPKVAYHPYPEDYGDIEIGSHRSSSSNLGTDDGYMPMTPGVALMG
GGSGSCKSDDYMPMSPTSVSAPKQILQPRAAAAAALPPTGPAVPAPANAAGRAFPENGAS
YKASSPAESSPEDSGYMRMWCGSKLSMENTDSKLLPNGDYLNMSPSDAGTSETPPDFFSA
ALHGGEMLRGVPGYCYSSLPRSYKAPYTCSGDNDQYVLMSSPVGRILEEERLEPQASVAT
TQSASALVAGVSGIGHTQPPHSAVPSPGRLGGSGSSRPEGFLNQRCRAVRPTRLSLEGLQ
TLPSMHEYPLPSEPKSPGEYINIDFGESGARLSPPAPPLLASAASSSSLLSASSPASSLG
SGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGTQTGDPVGSLDALLSPDASSRYPPLPP
RPAAPSSLKSQPPPPPSPGELYRLPPASTPQGPSAASSSSSETGDNGDYTEMAFGVAATP
PQPIVAPPKPEGARVTSPTSGMKRLSLMDQVSGVEAFLQAGQPPDPHRGAKVIRADPQGG
RRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGGSGVLSGGDEPPPS
PHQLQPQLTQQARPWTPSQPGGLVGCPGGSGSPMRRETSAGFQNGLNYIAIDVRDEPGSS
PPQQQHPQSQHPHPQPGDKSAWGRTRSLGGLISTVGAGSAGGVVGGPGPGALPSNTYASI
DFLSHHLKEATIVKE
NT seq
4008 nt
NT seq
+upstream
nt +downstream
nt
atggcgagcccgccgctgcacggcccccccgggccggcgggcagcgacggccccaacctc
aacaacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcag
aagcacggccacaaacgctttttcgtgctgcgcgggcccggcgcgagcggcgaggaggca
acggcgggtgggggtccagcaccgcagcctccgcggctcgagtactacgagaacgagaag
aagtggcggagcaaggcgggcgccccgaagcgggtcatctcgctcgactgctgcctgaac
atcaacaagcgcgccgacgccaagcacaagtacctgatcgccctctacaccaaggacgag
tactttgccgtggcggccgagaacgagcaggagcaggagggctggtaccgcgcgctcacc
gacctggtcagcgagggccgcgctggtgccggcgactcgaccctctcctccatcaccacc
gggtcctgcagtgcctctttgcctggcgccctgggcggctcagcgggtgctgatgagagc
tacgggctggtggcgcccgccacatcagtctaccgcgaggtatggcaggtgaacctgaag
ccaaagggtttgggccaaagcaagaacttgacaggcgtctaccgcctgtgtctgtccgct
cgcactattggtttcgtaaagctgaactgtgagcagccgtcggtgacgctgcagctcatg
aacatccgccgctgcggccactcggacagcttcttcttcatcgaggtgggccgctcagct
gtcaccggccctggcgagctgtggatgcaggccgacgactcggtggtggcccagaacatc
catgagaccatcctggaggccatgaaagcactcaaggagctcttcgagttccggccgcgc
agcaagagccagtcgtcgggctcctcagccacacatcccattagcgtccccggcgctcgc
aggcaccaccacctggtcaacctgccccccagccagactggcctggtgcgccgctcacgc
accgacagcctggctgccaccccgccggctaccaaatgcagctcatgccgggtgcgcacg
gccagcgagggcgacggcggcacggcggcgggaacgggggcggcgggtggaaggcccgtg
tcggtggctgggagccccctgagccccgggccggtgcgcgtgcccctgagccgctcgcac
accctgagcggtggctgcggtagccgtgtgagcaaggtgacactgcctccggcagggggc
gccctgcaacacagccgctccatgtccatgcccgtggcgcattcgcccccggcagccacc
agcccaggcagtctttcgtccagcagcgggcatggttcgggctcctacccactgcctccg
ggtccgcacacgcacctgcagcatcctctgcaccaccacacgagccagcggccctccagt
ggcagcgcctcagcctctggctcccccagcgatcccggcttcatgtccttggatgagtac
ggctccagccctggggatttgagagccttctgcagccacagaagcaacacacctgagtcc
attgccgagacacccccggcgaaggatgggagtgggagcgagctatacgggtacatgacc
atggacaggcccctgagccactgtggccgcccctaccgtcgggtctcaggggatggagct
caggacttggacagagggctgaggaagaggacttactccctgaccacacctgctcggcag
cggccggtgccccagccctcctctgcatctctggatgaatacactctcatgcgggccacc
ttctctggcagctcaggccgcctctgcccaacctgcccgacatcttctcccaaagtggcc
taccacccttatcctgaagactacggcgatattgagattgggtcccataggagctccagc
agtaacttgggcacggacgatggttacatgcccatgacccctggcgtggccctcatgggt
ggtggcagtggcagctgcaagagtgacgactacatgcccatgagccccaccagtgtgtct
gcccccaagcagatcctgcagccacgggctgctgctgctgcagccttgccccccactgga
cctgcagtgccggcacccgccaatgcggcaggcagggcctttccagagaacggggccagc
tacaaagctagctccccggctgaaagttctcccgaggacagtggatacatgcgtatgtgg
tgtggctccaagctgtccatggagaacaccgacagcaagctgcttcccaacggggactac
ctcaacatgtcccccagcgacgcgggcacttcagagaccccacccgacttcttctcggca
gccttgcatggcggagagatgctcaggggtgtccctggctactgctacagctctttgccc
cgctcctacaaggctccctacacttgcagtggggacaatgaccagtatgtgctcatgagc
tcccccgtgggtcgcatcctggaagaggagaggctggaacctcaggccagtgtggcgacc
acgcagtcggccagcgcccttgtggctggggtcagtgggattgggcacacccagcctcct
cactccgcagtgccttctccagggaggctaggtggcagcggcagtagccgcccagagggc
ttcctgaaccagcgttgccgggcagtgaggcccacgcgcctatccctggaggggctgcag
accttacccagcatgcacgagtaccctctaccgtcggagcccaaaagtcccggagagtat
atcaatattgactttggggagtctggagcccgcttgtcaccgcctgcccctccgctgctg
gcttcggcagcctcatcctcttcgctgctgtctgccagcagcccagcctcttccctgggc
tctggcaccccaggaactagcagcgacagccggcaacgctcaccactctctgactacatg
aacctcgacttcagttcgcccaagtcacccaaacctggtacccagactggtgacccagtg
ggctccttggatgccctcctatctcccgatgcctcctcccggtacccgccactgccccca
cgccctgctgccccctcctccttgaagtcacagccacctcccccaccctccccgggagag
ttgtaccgcctgcctcctgcatccactccccaaggccccagtgctgcctcctcttcgtcc
tcggagactggggacaatggtgactacaccgagatggcctttggcgtggctgccaccccg
ccacaacccatcgtggcccccccaaagccagaaggtgcccgtgtgaccagccccacatct
ggcatgaagaggctgagtctcatggatcaggtgtctggagttgaggcctttctgcaggct
ggccagcccccagacccacatcggggggccaaggtcatccgtgcagacccgcaggggggc
cgccgccgccacagctctgagaccttttcctcaaccaccactgtgactcccgtgtctcca
tcctttgcccacaacccgaagcgccacaactcggcctcggtggaaaatgtctctctcagg
aaaagcagcgaagggggtggcagcggtgtcctcagtgggggcgatgagccccctccatct
ccccaccagttgcaaccacagctcacccagcaggctcggccatggacaccaagtcagcct
gggggcctggttggctgccctgggggcagtggctctccaatgcgcagggagacgtctgct
ggctttcagaatggcctcaactacatcgccatcgatgtgagagatgagccagggtcctcg
ccaccccagcagcaacacccccaatcgcagcatccgcatccccagccaggcgacaagagc
gcctggggccggacccgtagccttgggggtctcatcagcactgtgggggctggcagtgct
ggtggggtggttggggggccaggccctggagccctgccttccaacacctatgccagcatc
gacttcttgtcccatcacctgaaggaggccaccattgtgaaagagtga
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