KEGG   Phyllostomus discolor (pale spear-nosed bat): 114512697
Entry
114512697         CDS       T07739                                 
Symbol
CDK4
Name
(RefSeq) cyclin-dependent kinase 4
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
pdic  Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic01522  Endocrine resistance
pdic04110  Cell cycle
pdic04115  p53 signaling pathway
pdic04151  PI3K-Akt signaling pathway
pdic04218  Cellular senescence
pdic04530  Tight junction
pdic04660  T cell receptor signaling pathway
pdic04933  AGE-RAGE signaling pathway in diabetic complications
pdic04934  Cushing syndrome
pdic05160  Hepatitis C
pdic05162  Measles
pdic05163  Human cytomegalovirus infection
pdic05164  Influenza A
pdic05165  Human papillomavirus infection
pdic05166  Human T-cell leukemia virus 1 infection
pdic05167  Kaposi sarcoma-associated herpesvirus infection
pdic05169  Epstein-Barr virus infection
pdic05200  Pathways in cancer
pdic05203  Viral carcinogenesis
pdic05212  Pancreatic cancer
pdic05214  Glioma
pdic05218  Melanoma
pdic05219  Bladder cancer
pdic05220  Chronic myeloid leukemia
pdic05222  Small cell lung cancer
pdic05223  Non-small cell lung cancer
pdic05224  Breast cancer
pdic05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:pdic00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    114512697 (CDK4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    114512697 (CDK4)
   04115 p53 signaling pathway
    114512697 (CDK4)
   04218 Cellular senescence
    114512697 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    114512697 (CDK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    114512697 (CDK4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    114512697 (CDK4)
   05203 Viral carcinogenesis
    114512697 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    114512697 (CDK4)
   05225 Hepatocellular carcinoma
    114512697 (CDK4)
   05214 Glioma
    114512697 (CDK4)
   05220 Chronic myeloid leukemia
    114512697 (CDK4)
   05218 Melanoma
    114512697 (CDK4)
   05219 Bladder cancer
    114512697 (CDK4)
   05224 Breast cancer
    114512697 (CDK4)
   05222 Small cell lung cancer
    114512697 (CDK4)
   05223 Non-small cell lung cancer
    114512697 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    114512697 (CDK4)
   05160 Hepatitis C
    114512697 (CDK4)
   05164 Influenza A
    114512697 (CDK4)
   05162 Measles
    114512697 (CDK4)
   05163 Human cytomegalovirus infection
    114512697 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    114512697 (CDK4)
   05169 Epstein-Barr virus infection
    114512697 (CDK4)
   05165 Human papillomavirus infection
    114512697 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    114512697 (CDK4)
   04934 Cushing syndrome
    114512697 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    114512697 (CDK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pdic01001]
    114512697 (CDK4)
Enzymes [BR:pdic01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     114512697 (CDK4)
Protein kinases [BR:pdic01001]
 Serine/threonine kinases: CMGC group
  CDK family
   114512697 (CDK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kdo Haspin_kinase ABC1 Kinase-like
Other DBs
NCBI-GeneID: 114512697
NCBI-ProteinID: XP_028387470
UniProt: A0A6J2NBY6
LinkDB
Position
2:159885205..159888290
AA seq 303 aa
METLRYEPVAEIGVGAYGTVYKARDPNSGHFVALKSVRVPNGGGAGGGLPVSTVREVALL
RRLEAFEHPNVVRLVDVCASSRTDRETRVTLVFEHVDQDLRTYLNKVPPPGLPVETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSSGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSAYATPVDLWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFSPRGPCPVQSVIPEMEESGAQLLLEMLAFNPHKRISAFRALQHSYLQKAEG
SPE
NT seq 912 nt   +upstreamnt  +downstreamnt
atggaaactcttcgatatgagccagtggctgagattggtgttggtgcctatgggacggtg
tacaaggcccgtgatcccaacagtggccactttgtggccctcaagagcgtgcgagtcccc
aatggaggaggtgctggaggaggccttcccgtcagcacagttcgtgaggtggccttactg
aggcggctggaagcttttgagcatcccaacgttgtccggctggtggatgtctgtgccagc
tcccgcactgaccgggagaccagagtgaccctggtgtttgagcatgtggaccaagacctg
aggacgtatctgaacaaggtacccccaccaggcttgccagtggagaccattaaggatctg
atgcgtcagtttctaagaggcctggatttccttcatgccaactgcattgttcaccgggac
ctgaagccagagaacattctggtgacaagtagtgggacagtcaagctggccgactttggc
ctggccagaatctacagctaccagatggcactcacacctgtggtcgtcacactctggtac
cgtgctccggaagttctgctgcagtctgcgtacgccacacctgtggacttgtggagtgtt
ggctgtatcttcgcagagatgtttcgccgaaagcctctcttctgcggaaactctgaagct
gaccagttaggcaaaatctttgatctgattgggctgcccccagaggatgactggccccga
gacgtgtctctgccccgaggagccttttcccccagagggccctgcccagtgcagtccgtg
atacctgagatggaagagtctggcgcacagctgctgctggagatgctggcttttaaccca
cataagcgaatctctgccttccgagccctgcagcactcttatctacaaaaggcagaaggt
agcccagaatga

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