Phyllostomus discolor (pale spear-nosed bat): 114514654
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Entry
114514654 CDS
T07739
Symbol
ADCY8
Name
(RefSeq) adenylate cyclase type 8 isoform X1
KO
K08048
adenylate cyclase 8 [EC:
4.6.1.1
]
Organism
pdic
Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic00230
Purine metabolism
pdic01100
Metabolic pathways
pdic01522
Endocrine resistance
pdic04015
Rap1 signaling pathway
pdic04020
Calcium signaling pathway
pdic04022
cGMP-PKG signaling pathway
pdic04024
cAMP signaling pathway
pdic04062
Chemokine signaling pathway
pdic04072
Phospholipase D signaling pathway
pdic04081
Hormone signaling
pdic04082
Neuroactive ligand signaling
pdic04114
Oocyte meiosis
pdic04211
Longevity regulating pathway
pdic04213
Longevity regulating pathway - multiple species
pdic04261
Adrenergic signaling in cardiomyocytes
pdic04270
Vascular smooth muscle contraction
pdic04371
Apelin signaling pathway
pdic04540
Gap junction
pdic04611
Platelet activation
pdic04713
Circadian entrainment
pdic04714
Thermogenesis
pdic04720
Long-term potentiation
pdic04723
Retrograde endocannabinoid signaling
pdic04724
Glutamatergic synapse
pdic04725
Cholinergic synapse
pdic04727
GABAergic synapse
pdic04742
Taste transduction
pdic04750
Inflammatory mediator regulation of TRP channels
pdic04911
Insulin secretion
pdic04912
GnRH signaling pathway
pdic04913
Ovarian steroidogenesis
pdic04914
Progesterone-mediated oocyte maturation
pdic04915
Estrogen signaling pathway
pdic04916
Melanogenesis
pdic04918
Thyroid hormone synthesis
pdic04921
Oxytocin signaling pathway
pdic04923
Regulation of lipolysis in adipocytes
pdic04925
Aldosterone synthesis and secretion
pdic04926
Relaxin signaling pathway
pdic04927
Cortisol synthesis and secretion
pdic04928
Parathyroid hormone synthesis, secretion and action
pdic04934
Cushing syndrome
pdic04935
Growth hormone synthesis, secretion and action
pdic04970
Salivary secretion
pdic04971
Gastric acid secretion
pdic04972
Pancreatic secretion
pdic04976
Bile secretion
pdic05032
Morphine addiction
pdic05163
Human cytomegalovirus infection
pdic05166
Human T-cell leukemia virus 1 infection
pdic05200
Pathways in cancer
pdic05207
Chemical carcinogenesis - receptor activation
pdic05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
pdic00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
114514654 (ADCY8)
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
114514654 (ADCY8)
04371 Apelin signaling pathway
114514654 (ADCY8)
04020 Calcium signaling pathway
114514654 (ADCY8)
04072 Phospholipase D signaling pathway
114514654 (ADCY8)
04024 cAMP signaling pathway
114514654 (ADCY8)
04022 cGMP-PKG signaling pathway
114514654 (ADCY8)
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
114514654 (ADCY8)
04081 Hormone signaling
114514654 (ADCY8)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
114514654 (ADCY8)
09144 Cellular community - eukaryotes
04540 Gap junction
114514654 (ADCY8)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
114514654 (ADCY8)
04062 Chemokine signaling pathway
114514654 (ADCY8)
09152 Endocrine system
04911 Insulin secretion
114514654 (ADCY8)
04923 Regulation of lipolysis in adipocytes
114514654 (ADCY8)
04912 GnRH signaling pathway
114514654 (ADCY8)
04913 Ovarian steroidogenesis
114514654 (ADCY8)
04915 Estrogen signaling pathway
114514654 (ADCY8)
04914 Progesterone-mediated oocyte maturation
114514654 (ADCY8)
04921 Oxytocin signaling pathway
114514654 (ADCY8)
04926 Relaxin signaling pathway
114514654 (ADCY8)
04935 Growth hormone synthesis, secretion and action
114514654 (ADCY8)
04918 Thyroid hormone synthesis
114514654 (ADCY8)
04928 Parathyroid hormone synthesis, secretion and action
114514654 (ADCY8)
04916 Melanogenesis
114514654 (ADCY8)
04925 Aldosterone synthesis and secretion
114514654 (ADCY8)
04927 Cortisol synthesis and secretion
114514654 (ADCY8)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
114514654 (ADCY8)
04270 Vascular smooth muscle contraction
114514654 (ADCY8)
09154 Digestive system
04970 Salivary secretion
114514654 (ADCY8)
04971 Gastric acid secretion
114514654 (ADCY8)
04972 Pancreatic secretion
114514654 (ADCY8)
04976 Bile secretion
114514654 (ADCY8)
09156 Nervous system
04724 Glutamatergic synapse
114514654 (ADCY8)
04727 GABAergic synapse
114514654 (ADCY8)
04725 Cholinergic synapse
114514654 (ADCY8)
04720 Long-term potentiation
114514654 (ADCY8)
04723 Retrograde endocannabinoid signaling
114514654 (ADCY8)
09157 Sensory system
04742 Taste transduction
114514654 (ADCY8)
04750 Inflammatory mediator regulation of TRP channels
114514654 (ADCY8)
09149 Aging
04211 Longevity regulating pathway
114514654 (ADCY8)
04213 Longevity regulating pathway - multiple species
114514654 (ADCY8)
09159 Environmental adaptation
04713 Circadian entrainment
114514654 (ADCY8)
04714 Thermogenesis
114514654 (ADCY8)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
114514654 (ADCY8)
05207 Chemical carcinogenesis - receptor activation
114514654 (ADCY8)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
114514654 (ADCY8)
05163 Human cytomegalovirus infection
114514654 (ADCY8)
09165 Substance dependence
05032 Morphine addiction
114514654 (ADCY8)
09166 Cardiovascular disease
05414 Dilated cardiomyopathy
114514654 (ADCY8)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
114514654 (ADCY8)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
114514654 (ADCY8)
Enzymes [BR:
pdic01000
]
4. Lyases
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.1 adenylate cyclase
114514654 (ADCY8)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Guanylate_cyc
AC_N
Adcy_cons_dom
TBK1_ULD
Motif
Other DBs
NCBI-GeneID:
114514654
NCBI-ProteinID:
XP_028389676
UniProt:
A0A6J2NCP3
LinkDB
All DBs
Position
7:complement(133083493..133240309)
Genome browser
AA seq
1254 aa
AA seq
DB search
MELSDVRCLSGSEELYTIHPTPPAGDGGSGSRPQRLLWQTAVRHITEQRFIHGHRGSGGG
GGGRSGGSGKGSDPAGGGPNHHASQLSGDSALPLYSLGPGERAHSSGGTKVFPERSGSGS
ASGSGGGGDLGFLHLDCAPSNSDFFLSGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQ
RRKSEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTT
SHTYLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGL
GTSLLQVILQVVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCV
EARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILF
ADVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQD
HAHCCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIA
NKLESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLSL
PEDIVKESVSCSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQA
LHVQSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLV
CAFIVLLFITAIQSLLPSSRVMPMAIQFSILIMLHSALVLITTAEDYKCLPLILRKTCCW
INETYLARNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFV
FTGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLRYDKLNHSGEDFLGT
KEASLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPS
HVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIAD
FDELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEI
NKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETY
LILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVL
GLVQSLNRQRQKQLLNENNNTGIIKGHYNRRTLLTPGGSEPGTQAEGADKSDLP
NT seq
3765 nt
NT seq
+upstream
nt +downstream
nt
atggagctctcggatgtgcgctgccttagcggcagcgaggaactctacaccatccacccg
acgcccccggccggcgacggcgggagcggctctcggccacagcggctgctgtggcagacg
gcggtgcggcacattaccgagcagcgcttcattcacgggcaccggggcagcggcggcggc
ggcggagggaggagtggaggctccggcaaaggctcggaccctgcaggcggcggccccaac
caccacgcttcgcagctgtccggcgactcggcgctgcctctctactccctggggccgggg
gagagggcgcacagctcggggggcaccaaagtcttcccggagcgcagcgggagcggcagc
gccagcggcagcgggggagggggcgacctgggcttcctgcacctcgactgcgccccaagc
aactcggacttcttcctcagcgggggctatagctaccgaggggtcatcttccccaccctg
cgcaactcgttcaagtcccgggatctggagcgcctctaccagcgctatttcctgggccag
aggcgcaaatccgaggtggtgatgaacgtgctggatgtgctgaccaaactcaccctgctg
gttctgcacttgagcctggcctcggcccccatggacccgctcaagggcattctgctgggc
ttcttcaccggcatcgaggtggtgatctgcgccctggtggtggtcaggaaggacaccacc
tctcacacgtacctgcagtacagcggcgtggtcacctgggtggccatgaccacccagatc
ttggccgcaggccttggctatgggctcctgggagacggcatcggctacgtgctcttcaca
cttttcgccacctacagcatgctgccgctgccgctcacctgggccatcctggccggcttg
ggcacctcgctgctgcaggtgatcctccaagtggtgatcccgcggctggcggtcatttcc
atcaaccaggttgtggcccaggctgtgttgttcatgtgcatgaacacagctggcatcttc
atcagctacctgtcagaccgggcccagcgccaggccttcctggagacgcggaggtgcgtg
gaggccaggctgcggctggagacggaaaaccagagacaggagcggctcgtgctgtccgtg
ctcccccgctttgtcgtcctggagatgatcaacgacatgaccaacgtggaagacgagcac
ctgcagcaccagttccaccggatctacatccaccgctacgagaacgtcagtattcttttt
gcagatgttaaaggattcaccaacctctccaccaccttgtctgctcaggagctggtcagg
atgctcaacgagctctttgccagatttgatcgactggcccatgagcatcactgtctccgc
atcaaaatcctaggggactgctactactgcgtttccggacttccggagccccgccaggac
catgcccactgctgtgtggaaatgggcctcagcatgatcaaaaccatcaggtatgtgcgg
tcaaggacgaagcatgatgtggacatgcgaatcgggatccactcgggctccgtgctgtgc
ggcgtgttgggcctgcgcaagtggcagtttgacgtctggtcctgggacgtggacattgcg
aacaaactggagtcgggaggaattcccgggaggattcacatctccaaggccacgctcgac
tgcctcaacggtgactacaacgtggaagagggccacgggaaagagaggaacgaattcttg
aggaagcataacatagagacctatttaattaagcagcccgaggagagtctgctgtccctg
cccgaagacatcgtcaaggagtcggtgagctgctcggacaggagaaacagcggggcgacg
ttcaccgaagggtcctggagccccgagctgcccttcgacaacatagtggggaaacagaac
actctggctgccctaacaagaaattcaataaatctacttccaaaccatcttgcacaagct
ttgcatgtccagtcggggcctgaggaaattaacaagcgcatagaacataccatcgacttg
cggagtggcgataaattgcgaagagagcatatcaagccattctcactgatgtttaaagac
tccagcctggagcacaagtattctcaaatgagggacgaagtgttcaagtcaaacttggtc
tgtgcgtttatcgttcttctgtttatcacggccatacaaagtttgcttccttcttcaagg
gtgatgcccatggccatccagttctccatcctgatcatgctgcactcggcactggtgctc
atcaccacggcggaggattacaagtgtctgcccctcatcctccggaaaacttgctgttgg
atcaatgaaacctatttggcccggaacgtcatcatctttgcgtccatcctgatcaacttc
ctaggcgccatcctaaatatcctgtggtgcgattttgacaagtcgatacccttgaagaac
ctgactttcaattcctcagctgtgtttacagatatctgctcctacccagagtactttgtc
ttcacgggcgtgctggccatggtgacctgtgcggtcttcctccgacttaactccgtcctg
aagctggccgtgctgctgatcatgatcgccatctacgccctgctgaccgagaccatctac
gcgggcctcttcctgcgctacgacaagctgaaccacagtggagaagacttcctggggacc
aaggaggcgtcgctgctgctgatggccatgttcctcctcgctgtgttctaccatggacag
cagctggagtacaccgcccgcctggacttcctctggcgagtccaggccaaagaggaaatc
aacgagatgaaggagctgagggagcacaacgagaacatgctccggaacatcctgcccagc
cacgtggcccgccatttcctggagaaggaccgagacaacgaggagctgtattcgcagtcc
tacgacgccgttggcgtgatgttcgcctccatcccggggtttgcggacttctactctcag
actgagatgaataaccagggagtggaatgcctgcgcctgctcaatgagatcattgccgac
ttcgatgagctgctcggcgaggaccggtttcaagacatcgaaaagatcaagaccattggc
agcacctacatggcggtctcaggtctgtcacctgaaaaacagcaatgcgaagacaagtgg
ggacacctgtgcgcgctggccgacttctccctcgccctgaccgagagcatccaggagatc
aacaagcactcgttcaacaacttcgagctccggatcggcatcagccacggttccgtggtg
gccggcgtcatcggcgctaagaaaccgcagtacgacatctggggcaaaaccgtgaacctg
gccagtcgcatggacagcaccggcgtcagcggcaggatccaagtcccagaggagacctat
ctcatcctgaaggaccagggcttcgcctttgactaccgaggggagatctacgtgaagggc
atcagcgagcaggaagggaaaatcaaaacgtactttctcctgggcagggtgcaacccaac
ccgttcatcttgcccccgaggaggctgccggggcagtactccctggccgccgtcgtgctg
ggcctcgtgcagtccctcaacaggcaaaggcagaagcagctcctcaacgagaacaacaac
acgggcatcatcaagggccactacaaccggcggactttgctgacccccggcgggtcggag
cccggaacccaagccgagggcgccgacaagtccgatttgccataa
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