Pseudomonas aeruginosa DK2: PADK2_16440
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Entry
PADK2_16440 CDS
T02161
Symbol
metH
Name
(GenBank) B12-dependent methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
pdk
Pseudomonas aeruginosa DK2
Pathway
pdk00270
Cysteine and methionine metabolism
pdk00450
Selenocompound metabolism
pdk00670
One carbon pool by folate
pdk01100
Metabolic pathways
pdk01110
Biosynthesis of secondary metabolites
pdk01230
Biosynthesis of amino acids
pdk04980
Cobalamin transport and metabolism
pdk04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
pdk00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
PADK2_16440 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
PADK2_16440 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
PADK2_16440 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
PADK2_16440 (metH)
04980 Cobalamin transport and metabolism
PADK2_16440 (metH)
Enzymes [BR:
pdk01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
PADK2_16440 (metH)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AFM65567
LinkDB
All DBs
Position
3566801..3570505
Genome browser
AA seq
1234 aa
AA seq
DB search
MSSPLTDRSARLQALQHALRERILILDGGMGTMIQSYKLEEADYRGERFADWPSDVKGNN
DLLLLSRPDVIQAIEKAYLDAGADILETNTFNATQVSQADYGMQSLAYELNVEGARLARQ
VADAKTAETPDKPRFVAGVLGPTSRTCSISPDVNNPGYRNVTFDELVENYVEATRGLIEG
GADLILIETIFDTLNAKAAIFAVQGVFEELGVELPIMISGTITDASGRTLSGQTTEAFWN
SVRHARPISVGLNCALGAKELRPYIEELSTKADTHVSAHPNAGLPNAFGEYDESPAEMAV
VVEEFAAAGFLNIVGGCCGTTPAHIEAIAKAVAKYPPRAIPEIPRACRLSGLEPFTIDRS
SLFVNVGERTNITGSAKFARLIREENYAEALEVAQQQVEAGAQVIDINMDEGMLDSKAAM
VTFLNLIASEPDISRVPIMIDSSKWEVIEAGLKCIQGKGIVNSISMKEGVEAFKHHARLC
KRYGAAVVVMAFDEDGQADTQARKEEICKRSYDILVDEVGFPPEDIIFDANIFAIATGIE
EHNNYAVDFINACAYIRDHLPYALSSGGVSNVSFSFRGNNPVREAIHSVFLYYAIRNGLT
MGIVNAGQLEIYDEIPKALRDRVEDVVLNRTPEATEALLAIADDYKGGGAVKEAEDEEWR
SYSVEKRLEHALVKGITTWIVEDTEECRQQCARPIEVIEGPLMSGMNVVGDLFGAGKMFL
PQVVKSARVMKQAVAHLIPFIEAEKGDKPEAKGKILMATVKGDVHDIGKNIVGVVLGCNG
YDVVDLGVMVPAEKILQTAIAEKCDIIGLSGLITPSLDEMVHVAKEMQRQNFQLPLMIGG
ATTSKAHTAVKIDPQYSNDAVVYVTDASRAVGVATSLLSKELKADYVARTRADYAVVRER
TANRSARTERLSYEQAIANKPAFDWAGYQAPTPSFTGVRVLDEIDLAVLAEYIDWTPFFI
SWDLAGKYPRILTDEVVGEAATSLFNDAQAMLKKLIDEKLIKARAVFGFWPANQVEHDDL
EVYGADGETLATLHHLRQQTIKPDGKPNLSLADFVAPKESGVRDYIGGFITTAGIGAEEV
AKAYEAKGDDYNSIMVKALADRLAEACAEWLHERVRKEYWGYARDEHLDNEALIKEQYVG
IRPAPGYPACPDHTEKGTLFELLDPQGLSGVSLTEHYAMFPAAAVSGWYFAHPQAQYFAV
GKIDKDQVERYSQRKGQEASVSERWLAPNLGYDD
NT seq
3705 nt
NT seq
+upstream
nt +downstream
nt
atgtccagcccgctcaccgatcgcagcgcccgcctgcaagccctccagcacgccctcagg
gaacgtatcctgatcctcgatggcggcatgggcaccatgatccagagctacaagctggaa
gaggccgactaccgcggcgagcgcttcgccgactggccgagcgacgtgaaaggcaacaac
gacctcttgctgctgagccgcccggacgtgatccaggccatcgagaaggcctacctcgac
gccggcgccgacatcctcgagaccaacaccttcaacgccacccaggtgtcccaggccgac
tacggcatgcagtcgctggcctacgaactcaacgtcgaaggggcgcgcctggcccgccag
gtggcggacgcgaagaccgccgagaccccggacaagccgcgcttcgtcgccggcgtgctc
ggcccgaccagccgcacctgctcgatttccccggacgtgaacaaccccggctaccgcaac
gtcaccttcgacgaactggtggagaactacgtcgaggcgacccgcggcctgatcgaaggc
ggcgccgacctgatcctgatcgagaccatcttcgacaccctcaacgccaaggcggcgatc
ttcgccgtccagggcgtgttcgaggaactcggcgtggagctgccgatcatgatctccgga
accatcaccgacgcctccggccgcaccctgtcgggccagaccaccgaggcattctggaac
tcggtgcggcatgcccggccgatctcggtaggcctgaactgcgccctcggcgccaaggaa
ttgcggccgtacatcgaggaactgtcgaccaaggccgacactcatgtctcggcccacccc
aacgccggcctgccgaacgccttcggcgaatacgacgaatcgccggcggaaatggccgtg
gtggtcgaggaattcgccgccgccggcttcctcaatatcgtcggcggctgctgcggcacc
accccggcgcacatcgaggcgatcgccaaggcagtggccaagtacccgccgcgggccatc
ccggagattccccgggcctgtcgcctgtccggcctggagccgttcaccatcgaccgcagc
tcgctgttcgtcaacgtcggcgagcgcaccaacatcaccggttcggccaagttcgcccgg
ctgatccgcgaggaaaactacgcggaagctctcgaggtcgcccagcagcaggtggaagcc
ggcgcccaggtgatcgacatcaacatggacgaaggcatgctggactcgaaggcggccatg
gtcaccttcctcaacctgatcgcctccgagcccgacatctcgcgcgtgccgatcatgatc
gactcctccaagtgggaagtgatcgaggccggcctgaagtgcatccagggcaagggcatc
gtcaactcgatctcgatgaaggaaggcgtcgaggccttcaagcaccatgcccgcctgtgc
aagcgctacggcgccgcggtggtggtgatggccttcgacgaggacggccaggccgacacc
caggcgcgcaaggaagaaatctgcaagcgctcctacgacatcctggtcgacgaagtcggc
ttcccaccggaagacatcatcttcgatgcgaacatcttcgccatcgccaccggcatcgag
gaacacaacaactacgcggtcgatttcatcaacgcctgcgcctacatccgcgaccacctg
ccctacgccctgagctcgggcggggtgtccaacgtgtccttctcgttccgcggcaacaac
ccggtacgcgaggcgatccactcggtgttcctctactacgcgatccgcaacggcctgacc
atgggcatcgtcaacgccggccagctggaaatctacgacgagattccgaaagcgctgcgc
gaccgggtcgaggacgtggtgctcaaccgcacgcccgaggccaccgaggccctgctggcg
atcgccgacgactacaagggcggcggcgcggtcaaggaggccgaggacgaggaatggcgc
agctacagtgtcgagaagcgcctcgagcatgcgctggtcaagggcatcaccacctggatc
gtcgaggacaccgaggaatgccgccagcagtgtgcgcgtcccatcgaggtcatcgaaggt
ccgctgatgtccgggatgaacgtggtcggcgacctgttcggcgccggcaagatgttcctc
ccgcaggtggtcaagtccgcgcgagtgatgaaacaggcggtggcccacctgattcccttc
atcgaggcggagaaaggcgacaagccggaagccaagggcaagatcctgatggccacggtg
aagggcgacgtgcacgacatcggcaagaacatcgtcggcgtggtgctcggctgcaacggc
tatgacgtggtcgacctcggcgtgatggtgccggcggagaagatcctgcagaccgccatc
gccgagaaatgcgacatcatcggcctgtctggcctgatcacgccgtcgctggacgagatg
gtccacgtcgccaaggaaatgcagcggcagaatttccagttgccgctgatgatcggcggc
gccactacctcgaaggcgcataccgcggtgaagatcgatccgcagtacagcaacgacgcg
gtggtctacgtcaccgacgcctcgcgcgcggtaggcgtggccaccagcctgctgtccaag
gagctgaaggccgactacgtggcccgcacccgcgccgactacgcggtggtccgcgaacgc
acggccaaccgcagcgcccgcaccgagcggctgagctacgaacaggcgatcgccaacaag
ccggcgttcgactgggccggctaccaggcgccgacgccttccttcaccggcgtcagggtg
ctcgacgagatcgacctcgcggtgctcgccgagtacatcgactggacgccgttcttcatt
tcctgggacctggccggcaagtacccgcgcatcctcaccgacgaggtggtcggcgaggcc
gccacctcgttgttcaacgacgcccaggcgatgctgaagaagctgatcgacgagaagctg
atcaaggcccgtgcggtgttcggcttctggccggccaaccaggtcgagcacgacgacctg
gaggtctacggcgccgatggcgagaccctcgccaccctgcaccacctgcggcagcagacg
atcaagccggacggcaagccgaacctgtcgctggccgatttcgtcgcgccgaaggaaagc
ggcgtgcgcgactacatcggcggcttcatcaccaccgccgggatcggcgccgaggaagtg
gccaaggcgtacgaagccaagggcgacgactacaacagcatcatggtcaaggcgctcgcc
gaccgcctcgccgaagcctgcgccgagtggctgcacgagcgggtgcgcaaggagtactgg
ggctacgcccgcgacgaacacctcgacaacgaggccttgatcaaggagcaatacgtcggc
atccgcccggcaccgggctacccggcctgccccgaccataccgagaaaggcaccctgttc
gaactgctcgacccgcagggcctgtccggcgtcagcctgaccgagcactacgcgatgttc
ccggccgcggcggtcagcggttggtatttcgcccacccgcaggcgcagtacttcgcggtc
ggcaagatcgacaaggaccaggtggaacgctacagccagcgcaagggccaggaagccagc
gtcagcgagcgctggctggcgccgaaccttggctacgatgactga
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