Phycodurus eques (leafy seadragon): 133410274
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Entry
133410274 CDS
T09682
Symbol
hsd3b1
Name
(RefSeq) hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
pee
Phycodurus eques (leafy seadragon)
Pathway
pee00140
Steroid hormone biosynthesis
pee01100
Metabolic pathways
Module
pee_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
pee_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
pee_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
pee00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
133410274 (hsd3b1)
Enzymes [BR:
pee01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
133410274 (hsd3b1)
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
133410274 (hsd3b1)
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Motif
Pfam:
3Beta_HSD
Epimerase
NAD_binding_4
Polysacc_synt_2
GDP_Man_Dehyd
RmlD_sub_bind
KR
NAD_binding_10
NmrA
adh_short
Motif
Other DBs
NCBI-GeneID:
133410274
NCBI-ProteinID:
XP_061547162
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Position
12:complement(9145979..9149156)
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AA seq
376 aa
AA seq
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MSCLDGDICVVTGACGFLGKTLIRMLVEQEKNIREIRLLDINVKQELLQSLEECRGDIKL
IAFEGDIRDSEFVRRACREATLVFHIASIIDVIDAVASSEMYGVNVKGTQNLLDACIQEN
VASFIYTSTVEVMGPNPEGEPVVNGHEDMAYRISLKFSYSKTKKEAEDRTLGCNGEPLQN
GGRLATCALRPMYIYGEDCRFLLGHMADGVRNGDVLYRMSMREAKVNPVYVGNVAAAHLQ
AARSLKDPARRADVGGKFYFVSDDTPHISYSDFNYAVMSPLGFSIQDRMAVPLRLFYVVC
FLWEMACLMLRPFRRVVPPINRQLLTMLNTAFSFSYDKAKCELGYVPKYTWQQARSNTTQ
WLAQQLPKQREKIWKK
NT seq
1131 nt
NT seq
+upstream
nt +downstream
nt
atgtcttgcctggacggcgacatatgcgtggtgacgggagcgtgcggcttcctgggaaag
acgctgatcaggatgctcgtggagcaggagaaaaacatccgcgagatacgactcctcgac
atcaacgtcaaacaggagctgctgcaaagtctggaagaatgccgaggcgacatcaagctg
atcgcatttgagggcgacatcagagacagcgaatttgtgaggagagcctgtcgagaagcc
acactggtcttccacatcgcgtccatcatcgacgtcatcgacgccgtggcgtccagtgag
atgtatggcgtcaacgtcaaaggaacacagaatctcttggacgcatgcatccaggagaat
gtggcctctttcatctacaccagcacagtggaggtgatgggtcccaaccccgagggtgag
ccagtggtgaacggccatgaggacatggcctaccggatctctctcaagttctcctacagc
aagaccaagaaggaggcagaggaccggaccctggggtgcaacggcgagcccctccaaaac
ggtgggcgcctggccacctgcgccctgcggcccatgtacatctatggcgaggactgccgc
ttcctgctcggccacatggcggacggcgtgcgcaacggcgacgtcctctaccggatgtct
atgcgggaggccaaggttaacccggtctacgtgggcaacgtggcggcggcccacctccag
gctgcccgcagcctcaaagaccccgcgcgtagagcggacgtgggcggaaagttctacttt
gtgtccgacgacacaccgcacatcagctactcggacttcaactacgcagtcatgtcgccg
ctgggctttagcatccaggacaggatggccgtgcccctgcgcctgttctacgtggtctgc
ttcctgtgggagatggcgtgcctgatgctgcggcccttccgcagggtagtgccgcccatc
aaccgccagctgctgaccatgctcaacacggccttcagcttctcgtatgacaaggccaag
tgcgagctgggctacgtgcccaagtacacctggcagcaggcaagaagcaacaccacccag
tggctcgcacagcagctgcccaaacaacgggagaaaatatggaaaaagtaa
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