Paenibacillus sp. E222: HW560_18945
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Entry
HW560_18945 CDS
T10443
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
pezz Paenibacillus sp. E222
Pathway
pezz00270
Cysteine and methionine metabolism
pezz00450
Selenocompound metabolism
pezz00670
One carbon pool by folate
pezz01100
Metabolic pathways
pezz01110
Biosynthesis of secondary metabolites
pezz01230
Biosynthesis of amino acids
pezz04980
Cobalamin transport and metabolism
pezz04981
Folate transport and metabolism
Module
pezz_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
pezz00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
HW560_18945 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
HW560_18945 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
HW560_18945 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
HW560_18945 (metH)
04980 Cobalamin transport and metabolism
HW560_18945 (metH)
Enzymes [BR:
pezz01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
HW560_18945 (metH)
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GFIT
Motif
Pfam:
S-methyl_trans
Met_synt_B12
Pterin_bind
B12-binding_2
B12-binding
MtrH
CdhD
Motif
Other DBs
NCBI-ProteinID:
QLG39977
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Position
4180000..4183440
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AA seq
1146 aa
AA seq
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MDKLSLHDALKQRILILDGAMGTMIQQVELTGADFGGEDLDGCNEMLVLTRPELIQRIHE
EYLEAGADLIETNTFGATSVVLAEYDIQDRAREINLEAARIAKAAADRFSTPESPRYVVG
AMGPTTKTLSVTGGVTFQELIDSYFEQALALIEGGVDALLLETSQDTLNVKAGSIGIQQA
FEQSGIKLPLMISGTIEPMGTTLAGQNIESFYISLEHLNPISVGLNCATGPEFMRDHIRS
LSGMASVAVSCYPNAGLPDENGNYHESPDSLAQKIGAFAEQGWLNIAGGCCGTTPAHIRA
MRDTLAKYPPREMNGTHPPALSGIDPVYVEQDNRPYMVGERTNVLGSRKFKRLIVEGKYE
EASEIARAQVKNGAHVVDVCVQDPDREEAEDMEKFLELVVKKVKVPLMIDTTDAAVIDLA
LQYSQGKAIINSINLEDGEEKFELVTPLLHKYGGAVVVGTIDERGQAISREDKLEVAKRS
YDLLVNKYGLKAEDLIFDTLVFPVGTGDEQYIGSAKETIEGIRVIKEAMPECHTILGISN
ISFGLPEAGREVLNSVFLYECTKAGLDYAIVNTEKLERYASIPEEERRLSEELLYNTNDE
TLAAFVAAFRNKKVEKKEKISNLSLEERLASYVVEGSKEGLLPDLEQALTKYTALEVING
PLMRGMEEVGRLFNNNELIVAEVLQSAEVMKASVAYLEQFMEKNETSVKGKIILATVKGD
VHDIGKNLVEIILSNNGYRIINLGIKVPPERIIEAYREEKVDAIGLSGLLVKSAQQMILT
AQDLRTAGIDVPIMVGGAALTRKFTKNRIRPEYNGMVVYAKDAMDGLDLANKLMNPSTRE
VMQLEMDAEKEADAAGAETVTSLPELTRVERSDIAIDNPVLVPPDLERHVMRNYPLSHIL
PYVNMQMLLGHHLGLRGSVEQLLASGDQKATDLKAVVDDIMQEAVRDGIIQAHAMYRFFP
AQSSGNSVIIYDPEDTSNILHTFTFPRQKVEPYLCLSDFLKPVESGQMDYVGFMVVTAGH
GVRELSTAWKEQGDYLRSHALQSVALEVAEGLAERVHHMMRDIWGFPDPAQMTMKQRHGA
RYQGIRVSFGYPACPDLEDQGPLFKLLQPEDIGVELTEGFMMEPEASVSAMVFSHPQAKY
FNVDKA
NT seq
3441 nt
NT seq
+upstream
nt +downstream
nt
ttggataagcttagcttacatgatgcattaaaacaacgaatattgatcctcgacggtgca
atggggacaatgattcagcaggttgaactcacaggcgcagattttggcggagaagacctg
gatgggtgtaatgaaatgcttgtacttacacgtccagagctgatccagcgtattcatgag
gaatatctggaagccggtgctgacttgattgaaacaaatacgtttggtgcaacttcagtt
gtacttgctgaatatgacattcaggaccgtgcacgtgaaattaatctcgaagcagccaga
attgcaaaagcggccgcggatcgattctcgacaccggagtctccacgttatgtggtcggc
gctatgggccctactaccaaaacgctgtctgtaacaggtggagtaacgttccaagaactc
atcgacagttattttgagcaagcgcttgctttaattgagggaggcgttgatgcgctgctg
cttgaaacctcacaagatacgcttaatgtaaaagcaggtagcattggaattcaacaggca
ttcgagcaaagtggtatcaagcttcccttgatgatctcaggaacgatcgaaccgatgggt
acaaccctcgctggtcagaatattgagtctttttatatatccttagaacaccttaaccca
atttcagtgggactaaactgtgctacaggtccggaattcatgcgtgaccatattcgctcg
ctttccgggatggcttcagttgcggtaagttgttatccaaatgcaggtcttccggatgag
aacggtaattaccatgaatcccctgattcgcttgctcagaaaatcggcgcttttgccgag
cagggctggttgaacattgcgggtggctgctgtgggacaacacctgcacatattcgggca
atgcgggatacacttgccaagtaccctccaagagaaatgaatggaacacatccaccagca
ttgtcgggaattgatccagtctacgttgaacaggacaatcgcccttacatggttggggaa
cgtacgaacgtacttggatcacggaaattcaagcgtcttattgttgaagggaaatatgaa
gaagcttcggaaattgctcgggctcaggtgaaaaatggggcacatgttgtcgacgtttgt
gttcaagacccggaccgtgaagaagccgaagatatggagaaattccttgaacttgttgtc
aaaaaagtaaaggtgccacttatgatcgatacgacggatgcagccgttatcgatcttgca
ctgcaatactctcaaggtaaagcgataattaactccattaaccttgaggacggcgaggaa
aagttcgagctggtcactccgctcttgcataaatatggcggtgctgtcgttgtcggaacg
attgatgaacgtggtcaggccattagtcgtgaggacaagctggaggtagccaagcgatct
tacgatttgctggtgaacaaatatgggttaaaagcagaagacctaatttttgacaccctg
gtgtttccagtagggacgggcgatgaacagtatatcggttccgccaaagaaacaattgaa
ggtattcgtgtcattaaagaagcgatgcctgaatgtcatacgatactggggatcagtaac
atttcatttggattgcctgaagcagggcgtgaagtgctgaactctgtatttttatatgag
tgtaccaaagcaggtctcgattatgccatcgttaatacagagaagctggagcgttatgca
tccattccggaagaagagcgcagactctcggaagagctgttatataatacgaatgacgag
acactggctgctttcgtagcggcgttccgtaacaaaaaggtcgagaaaaaagaaaagatt
tcgaacctgtcgttggaagaacgtctcgcatcctatgttgttgaaggaagtaaagaaggc
ttgctgcccgatctggagcaggcactgaccaaatatacagcccttgaagtaatcaatgga
ccgctgatgcggggcatggaagaagtagggcgactgtttaacaataatgagttgatcgta
gcagaggtgcttcagagcgcggaagtcatgaaggcttcggtagcttatttggaacagttc
atggagaagaatgagacgtcagttaaagggaaaattattctggcgacggtcaagggcgat
gtacacgacatcggcaaaaaccttgtggagatcatcctttccaataacggttaccggatc
attaatttgggtataaaagtaccaccagagcgaattatcgaggcgtacagagaagaaaaa
gtcgatgcgatcggtctatccggtctgttggtaaaatcggcgcagcagatgattcttacc
gctcaggacttgcgtacagcaggaattgatgtacctattatggttggtggagcggcattg
acacgcaaattcaccaagaatcgtatacgcccggaatataacggcatggttgtatatgca
aaagatgcgatggacggtctggatttggccaacaagctcatgaacccaagcactcgtgaa
gtgatgcagctggagatggacgcagaaaaagaggcggacgcagctggtgcagaaaccgtt
acctcacttcctgagcttacacgggtagaacgttcggatatcgcaatagacaacccggtc
cttgttccgccggatctggaacgacatgttatgcgaaattatccgctatcacacatctta
ccgtatgtgaacatgcagatgttgctaggtcaccatcttggtttgcgtggctcagtagag
cagttgcttgcttcgggtgatcagaaagctactgacctgaaagcggtagtggatgatatt
atgcaggaagctgttcgtgacgggattattcaggctcatgcgatgtatcgtttcttccct
gctcagtccagcggtaacagcgtcattatctatgacccggaggatacaagcaatatcctg
catacattcacgttccctcgtcaaaaagttgaaccatacctctgcctgtccgatttcttg
aagccagtggaatccggacaaatggattacgttggtttcatggtcgttacggctgggcac
ggtgtacgggagttatcgacagcttggaaggagcaaggtgattatcttcgctcacatgct
ctgcaatccgtagcgcttgaagtagcagagggattagctgagcgggttcatcatatgatg
agagatatctggggattcccggatccagcacagatgaccatgaagcagcgtcatggagca
cgctatcagggaatcagggtatcattcggatatccggcttgtcccgatttggaagaccaa
gggccgcttttcaagttgttacagcctgaggatattggtgtggaattgactgaaggtttc
atgatggaacctgaagcatccgtatcagcgatggtattcagccacccgcaagcgaagtat
tttaacgtggataaggcttaa
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