Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1: PFREUD_10250
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Entry
PFREUD_10250 CDS
T01252
Symbol
odhA
Name
(GenBank) 2-oxoglutarate dehydrogenase, E1 and E2 components
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
pfr
Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1
Pathway
pfr00020
Citrate cycle (TCA cycle)
pfr00630
Glyoxylate and dicarboxylate metabolism
pfr00785
Lipoic acid metabolism
pfr01100
Metabolic pathways
pfr01110
Biosynthesis of secondary metabolites
pfr01120
Microbial metabolism in diverse environments
pfr01200
Carbon metabolism
pfr01210
2-Oxocarboxylic acid metabolism
Module
pfr_M00009
Citrate cycle (TCA cycle, Krebs cycle)
pfr_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
pfr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
PFREUD_10250 (odhA)
00630 Glyoxylate and dicarboxylate metabolism
PFREUD_10250 (odhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
PFREUD_10250 (odhA)
Enzymes [BR:
pfr01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
PFREUD_10250 (odhA)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
PFREUD_10250 (odhA)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
PFREUD_10250 (odhA)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
PFREUD_10250 (odhA)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
2-oxoacid_dh
E1_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
CBL56549
UniProt:
D7GDD8
LinkDB
All DBs
Position
complement(1154235..1158020)
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AA seq
1261 aa
AA seq
DB search
MGTDKFGANDWLIADMRQRYLADPTSVDERWRAYFQALGVTPDPSTPVASPAPVTPAPTQ
APTPQAPTPQAPTSSAPGPNEPAQPPSSRVQAPVPTLEPREIRRNAPEQPGMGGGLSADV
PNPAVRPAKKAEGQATRTVLRGIPKTTAVNMNESLSVPTATSVRQVPMKLVIDNRALVNS
FMARTRGGKVSFTHIIAFAMVQAIRDVPEMNHSFDMTDGKPTLVENPAINLGIAIDTTAK
NGTRELLVPNIKDAGNLDFAQFWSAYEDLVDRTRSGKLTLEDYAGTTVSITNPGGIGTNM
SVPRLMSGQAMIMGVGSIDYPAAFQGTSTQRTNDAAISKVCTLTSTYDHRIIQGAVSGEF
LRRIHQLLLGADGFYEHIYEALRIPYPPLHWDRDFTANSQSEISKGARVTELIQAYRAEG
HLLADLDPVEYRMRTHPDLDLATHGLSIWDLDREFPVGRFGGEEGRHIVLRQMLDILRES
YCYTLAIEYMHIDDPEERAWVQERFERPRKPRPREEHLLILDRLSEAEVFETFLQTKYVG
QTRFSMEGAESSIVILSELCAAAADGGMAEVSIGMPHRGRLNVLTNVVGKLYSQVFREFD
NKVPTEEDITGDVKYHLGATGQFTAMSGEKIKVSLAANPSHLEAVDPVLEGIARAKRDRQ
PVPADYPVLPILMHGDASFSAQGIVYEVLQMSQLRPYRVGGTVHLVVNNQLGFTTSPSDG
RSSKYCTDVAKALGAPVIHVNGDDPDACARAAELAFDFRARFHKDVVIDMVCYRLRGHNE
GDDPSFTQPQMYDLVARKGSVRKIYTDALIGRGDISVEDAEQAVNRFRARLEEVFSMVRN
PEIPRDEVDHQVAYRLAPQYPAKERAASAPPTPTREQFERVADVYENLPEGFTPHPKVGP
QLKRRADSIHNGPVDWATAELLAFGTLLQDRRHVRLVGQDTRRGTFSQRFGAVVDRVTNE
AWVPLKHLSDDQAPFDIYDSNLTEYAGMGFEYGYSTAAPDALVLWEAQYGDFANGAQTIA
DEFISSGFAKWQQRSGVVLLLPHGYEGAGPDHSSCRIERWLQTADEGNIAVTMPSTAASY
FHLLRQHAYVNWHRPLVVATPKSMLRNKAAASPLSDLLDEPWRPALADPTITDPGAVRRV
LLCAGKIRWDLVAERRKLGLDGQIAIVSLERLFPLPTAELAEILRAFPQVNDFRYVQEEP
ENQGAWEFMDRFLTPALSEALNRPFRMRPVTRPRSSAPSVGSHTVHLAQQRSLLAESLGQ
D
NT seq
3786 nt
NT seq
+upstream
nt +downstream
nt
atgggtactgacaaatttggggccaatgactggctcattgccgatatgcgccagcgctat
ctggcagatcccacttctgttgatgagaggtggcgcgcatacttccaggcactgggagtc
acgcccgatccgtcaacgccggtggcaagcccggccccggtgaccccggcgccaacgcag
gcccccaccccgcaggcccccaccccgcaagcaccgacctcgagcgcaccggggcccaat
gaacctgcccaaccaccgtccagccgcgttcaggcccccgtccccaccctcgagccccgc
gagatccggcggaacgcccccgagcagcccggcatgggtggcggcctgtccgccgacgtg
cccaacccggcagtccgtcccgccaagaaggcggagggccaggccacccgcaccgtgctg
cgcggcattccgaagaccaccgccgtcaacatgaacgaatcgctgtcggtgcccacggcc
acgtccgttcgccaggtgccgatgaagctcgtcatcgacaaccgggcgctggtcaacagc
ttcatggcccgcacccgcggcgggaaggtgagcttcacccacatcatcgccttcgccatg
gtgcaggccatccgtgacgtcccggagatgaaccactcgttcgacatgaccgacggcaag
ccgacgctcgtggagaacccggcgatcaacctggggatcgcgatcgacacgacggcgaag
aacggcacccgggagctgttggtgcccaacatcaaggacgccggcaacttggactttgcg
cagttctggtcggcctacgaggatctcgtggaccgcacccggtcgggcaagctgacgttg
gaggactacgccggcaccacggtgtcgatcaccaacccgggcggcatcggcaccaacatg
tcggtgccgcgcctgatgagcggccaggccatgatcatgggcgtcggaagcatcgactat
ccggccgccttccagggaaccagcacgcagcgcaccaacgacgccgcgatctccaaggtc
tgcaccctgacgtccacctatgaccaccgcatcatccagggggccgtctccggggaattc
ctgcgtcgcatccaccaattgctcctgggcgccgacggcttctacgagcacatctatgag
gcacttcggatcccctatcccccgctgcactgggaccgcgatttcaccgcgaactcgcag
tcggagatctccaagggcgcccgcgtcaccgaactgatccaggcctaccgggccgagggc
cacctgctggccgacctcgatccggtggagtaccggatgcgcacccaccccgacctcgac
ctggccacacatggcctgtccatctgggaccttgaccgtgagttccctgtgggccgcttc
ggtggcgaggaggggcgccacatcgtgctgcgccagatgctcgacatcctgcgcgagtcg
tactgctacacgctggccatcgagtacatgcacatcgacgatcccgaggaacgggcatgg
gtgcaggaacgcttcgagcgtccgcgtaagccccgcccccgggaggaacacctgctgatc
cttgaccggctcagtgaggcggaggtcttcgagaccttcctgcagacgaagtacgtcggg
cagacgcggttcagcatggagggcgcggagtcgtccatcgtcatcctgtcggaactgtgt
gcggccgccgccgatggtggaatggccgaggtgagcatcgggatgccccaccgtgggcgg
ctcaatgtgctgaccaatgtggtgggcaagctctacagccaggtgttccgcgagttcgac
aacaaggtgcccaccgaggaggacatcaccggcgatgtgaaataccacctcggcgcgacc
ggccagttcacggccatgtcgggggagaagatcaaggtctcgttggccgcgaatcccagc
cacctggaggccgtcgatccggtgctggagggcattgcgcgggccaagcgtgatcgtcag
ccggttcccgccgactaccccgtgttgccgatcctcatgcacggcgacgcgtcgttctcg
gcgcagggcatcgtctacgaggtgctgcagatgagccagctgcgcccctaccgggtgggc
ggcaccgtgcacctggtggtcaacaaccagctgggcttcaccacctcacccagcgacggg
cgttcctcgaagtactgcaccgatgtggccaaggccctcggggcaccggtgatccacgtg
aacggcgacgatcccgatgcctgtgcccgggccgccgaactcgccttcgacttccgggcc
cgcttccacaaggacgtcgtcatcgacatggtctgctaccgcctgcgcggtcacaatgag
ggtgacgatcccagcttcacccaaccgcagatgtatgacctggtggcccgcaagggttcg
gtgcgcaaaatctacaccgacgccctgatcgggcgcggcgacatctcggtggaggatgcc
gagcaggcggtcaaccgcttccgggcccgtctcgaggaagtgttctcgatggtccgcaat
cccgagatcccccgcgacgaggtggaccatcaggttgcgtaccgcctggcgccccagtac
ccggccaaggaacgggccgccagcgccccgcccactcccacccgggagcagttcgagcgg
gtggccgacgtctatgagaacctgcccgaggggttcaccccgcatccgaaggtgggtccc
cagctcaagcggcgcgctgattccatccacaatggtccggtcgattgggcgaccgcggag
ctgttggccttcggcacgctgctgcaggatcgtcgccacgtgcgcctcgtcggacaggac
acccgtcggggaaccttcagccagcgcttcggtgccgtggtcgatcgggtgaccaacgag
gcctgggtgccgttgaagcacctgtcggacgatcaggcccccttcgacatctatgactcg
aacctcaccgaatatgccgggatgggctttgagtacgggtactcgacggccgctccggac
gccctggtgctgtgggaggcccagtacggcgacttcgccaatggcgcccagaccattgcc
gacgagttcatctcctcgggcttcgccaagtggcagcaacgctccggcgtcgtcctgctg
cttccgcacggctatgagggtgcgggacccgatcattcgtcgtgccgcatcgaacgctgg
ttgcaaaccgccgacgaggggaacatcgccgtgacgatgcccagcacggcggcaagctac
ttccacctgctgcgccagcacgcctatgtgaactggcaccgtccgctggtggtggccaca
ccgaagtcgatgttgcgcaacaaggcggcggccagcccactgagtgacctgctggacgag
ccctggcggcccgcgctggccgatcccaccatcaccgatcccggagccgtgcggcgcgtc
ctgctgtgcgccggcaagatccgctgggacctggtggccgagcgccgcaagctcggtctg
gacgggcagatcgccatcgtctccctggagcggttgttcccgctgccgaccgccgagctc
gccgagatcctccgggcgttcccgcaggtcaacgacttccgctacgtgcaggaggagccc
gagaaccagggggcctgggaattcatggaccgcttcctgacccccgcgctctcggaggcg
ctgaacaggcccttccggatgcgtccggtcacccggccccgttcgtcggcgccctcggtc
ggctcccacaccgtgcacctggcgcagcagcgctcgttgctggcggaatcgctcggccag
gactga
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