Propionibacterium freudenreichii subsp. freudenreichii DSM 20271: RM25_1150
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Entry
RM25_1150 CDS
T03860
Name
(GenBank) 2-oxoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
pfre
Propionibacterium freudenreichii subsp. freudenreichii DSM 20271
Pathway
pfre00020
Citrate cycle (TCA cycle)
pfre00630
Glyoxylate and dicarboxylate metabolism
pfre00785
Lipoic acid metabolism
pfre01100
Metabolic pathways
pfre01110
Biosynthesis of secondary metabolites
pfre01120
Microbial metabolism in diverse environments
pfre01200
Carbon metabolism
pfre01210
2-Oxocarboxylic acid metabolism
Module
pfre_M00009
Citrate cycle (TCA cycle, Krebs cycle)
pfre_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
pfre00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
RM25_1150
00630 Glyoxylate and dicarboxylate metabolism
RM25_1150
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
RM25_1150
Enzymes [BR:
pfre01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
RM25_1150
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
RM25_1150
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
RM25_1150
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
RM25_1150
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Gene cluster
GFIT
Motif
Pfam:
2-oxoacid_dh
E1_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AJQ90866
LinkDB
All DBs
Position
1324057..1327842
Genome browser
AA seq
1261 aa
AA seq
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MGTDKFGANDWLIADMRQRYLADPTSVDERWRAYFQALGVTPDPSTPVASPAPVTPAPTQ
APTPQAPTPQAPTSSAPGPNEPAQPPSSRVQAPVPTLEPREIRRNAPEQPGMGGGLSADV
PNPAVRPAKKAEGQATRTVLRGIPKTTAVNMNESLSVPTATSVRQVPMKLVIDNRALVNS
FMARTRGGKVSFTHIIAFAMVQAIRDVPEMNHSFDMTDGKPTLVENPAINLGIAIDTTAK
NGTRELLVPNIKDAGNLDFAQFWSAYEDLVDRTRSGKLTLEDYAGTTVSITNPGGIGTNM
SVPRLMSGQAMIMGVGSIDYPAAFQGTSTQRTNDAAISKVCTLTSTYDHRIIQGAVSGEF
LRRIHQLLLGADGFYEHIYEALRIPYPPLHWDRDFTANSQSEISKGARVTELIQAYRAEG
HLLADLDPVEYRMRTHPDLDLATHGLSIWDLDREFPVGRFGGEEGRHIVLRQMLDILRES
YCYTLAIEYMHIDDPEERAWVQERFERPRKPRPREEHLLILDRLSEAEVFETFLQTKYVG
QTRFSMEGAESSIVILSELCAAAADGGMAEVSIGMPHRGRLNVLTNVVGKLYSQVFREFD
NKVPTEEDITGDVKYHLGATGQFTAMSGEKIKVSLAANPSHLEAVDPVLEGIARAKRDRQ
PVPADYPVLPILMHGDASFSAQGIVYEVLQMSQLRPYRVGGTVHLVVNNQLGFTTSPSDG
RSSKYCTDVAKALGAPVIHVNGDDPDACARAAELAFDFRARFHKDVVIDMVCYRLRGHNE
GDDPSFTQPQMYDLVARKGSVRKIYTDALIGRGDISVEDAEQAVNRFRARLEEVFSMVRN
PEIPRDEVDHQVAYRLAPQYPAKERAASAPPTPTREQFERVADVYENLPEGFTPHPKVGP
QLKRRADSIHNGPVDWATAELLAFGTLLQDRRHVRLVGQDTRRGTFSQRFGAVVDRVTNE
AWVPLKHLSDDQAPFDIYDSNLTEYAGMGFEYGYSTAAPDALVLWEAQYGDFANGAQTIA
DEFISSGFAKWQQRSGVVLLLPHGYEGAGPDHSSCRIERWLQTADEGNIAVTMPSTAASY
FHLLRQHAYVNWHRPLVVATPKSMLRNKAAASPLSDLLDEPWRPALADPTITDPGAVRRV
LLCAGKIRWDLVAERRKLGLDGQIAIVSLERLFPLPTAELAEILRAFPQVNDFRYVQEEP
ENQGAWEFMDRFLTPALSEALNRPFRMRPVTRPRSSAPSVGSHTVHLAQQRSLLAESLGQ
D
NT seq
3786 nt
NT seq
+upstream
nt +downstream
nt
atgggtactgacaaatttggggccaatgactggctcattgccgatatgcgccagcgctat
ctggcagatcccacttctgttgatgagaggtggcgcgcatacttccaggcactgggagtc
acgcccgatccgtcaacgccggtggcaagcccggccccggtgaccccggcgccaacgcag
gcccccaccccgcaggcccccaccccgcaagcaccgacctcgagcgcaccggggcccaat
gaacctgcccaaccaccgtccagccgcgttcaggcccccgtccccaccctcgagccccgc
gagatccggcggaacgcccccgagcagcccggcatgggtggcggcctgtccgccgacgtg
cccaacccggcagtccgtcccgccaagaaggcggagggccaggccacccgcaccgtgctg
cgcggcattccgaagaccaccgccgtcaacatgaacgaatcgctgtcggtgcccacggcc
acgtccgttcgccaggtgccgatgaagctcgtcatcgacaaccgggcgctggtcaacagc
ttcatggcccgcacccgcggcgggaaggtgagcttcacccacatcatcgccttcgccatg
gtgcaggccatccgtgacgtcccggagatgaaccactcgttcgacatgaccgacggcaag
ccgacgctcgtggagaacccggcgatcaacctggggatcgcgatcgacacgacggcgaag
aacggcacccgggagctgttggtgcccaacatcaaggacgccggcaacttggactttgcg
cagttctggtcggcctacgaggatctcgtggaccgcacccggtcgggcaagctgacgttg
gaggactacgccggcaccacggtgtcgatcaccaacccgggcggcatcggcaccaacatg
tcggtgccgcgcctgatgagcggccaggccatgatcatgggcgtcggaagcatcgactat
ccggccgccttccagggaaccagcacgcagcgcaccaacgacgccgcgatctccaaggtc
tgcaccctgacgtccacctatgaccaccgcatcatccagggggccgtctccggggaattc
ctgcgtcgcatccaccaattgctcctgggcgccgacggcttctacgagcacatctatgag
gcacttcggatcccctatcccccgctgcactgggaccgcgatttcaccgcgaactcgcag
tcggagatctccaagggcgcccgcgtcaccgaactgatccaggcctaccgggccgagggc
cacctgctggccgacctcgatccggtggagtaccggatgcgcacccaccccgacctcgac
ctggccacacatggcctgtccatctgggaccttgaccgtgagttccctgtgggccgcttc
ggtggcgaggaggggcgccacatcgtgctgcgccagatgctcgacatcctgcgcgagtcg
tactgctacacgctggccatcgagtacatgcacatcgacgatcccgaggaacgggcatgg
gtgcaggaacgcttcgagcgtccgcgtaagccccgcccccgggaggaacacctgctgatc
cttgaccggctcagtgaggcggaggtcttcgagaccttcctgcagacgaagtacgtcggg
cagacgcggttcagcatggagggcgcggagtcgtccatcgtcatcctgtcggaactgtgt
gcggccgccgccgatggtggaatggccgaggtgagcatcgggatgccccaccgtgggcgg
ctcaatgtgctgaccaatgtggtgggcaagctctacagccaggtgttccgcgagttcgac
aacaaggtgcccaccgaggaggacatcaccggcgatgtgaaataccacctcggcgcgacc
ggccagttcacggccatgtcgggggagaagatcaaggtctcgttggccgcgaatcccagc
cacctggaggccgtcgatccggtgctggagggcattgcgcgggccaagcgtgatcgtcag
ccggttcccgccgactaccccgtgttgccgatcctcatgcacggcgacgcgtcgttctcg
gcgcagggcatcgtctacgaggtgctgcagatgagccagctgcgcccctaccgggtgggc
ggcaccgtgcacctggtggtcaacaaccagctgggcttcaccacctcacccagcgacggg
cgttcctcgaagtactgcaccgatgtggccaaggccctcggggcaccggtgatccacgtg
aacggcgacgatcccgatgcctgtgcccgggccgccgaactcgccttcgacttccgggcc
cgcttccacaaggacgtcgtcatcgacatggtctgctaccgcctgcgcggtcacaatgag
ggtgacgatcccagcttcacccaaccgcagatgtatgacctggtggcccgcaagggttcg
gtgcgcaaaatctacaccgacgccctgatcgggcgcggcgacatctcggtggaggatgcc
gagcaggcggtcaaccgcttccgggcccgtctcgaggaagtgttctcgatggtccgcaat
cccgagatcccccgcgacgaggtggaccatcaggttgcgtaccgcctggcgccccagtac
ccggccaaggaacgggccgccagcgccccgcccactcccacccgggagcagttcgagcgg
gtggccgacgtctatgagaacctgcccgaggggttcaccccgcatccgaaggtgggtccc
cagctcaagcggcgcgctgattccatccacaatggtccggtcgattgggcgaccgcggag
ctgttggccttcggcacgctgctgcaggatcgtcgccacgtgcgcctcgtcggacaggac
acccgtcggggaaccttcagccagcgcttcggtgccgtggtcgatcgggtgaccaacgag
gcctgggtgccgttgaagcacctgtcggacgatcaggcccccttcgacatctatgactcg
aacctcaccgaatatgccgggatgggctttgagtacgggtactcgacggccgctccggac
gccctggtgctgtgggaggcccagtacggcgacttcgccaatggcgcccagaccattgcc
gacgagttcatctcctcgggcttcgccaagtggcagcaacgctccggcgtcgtcctgctg
cttccgcacggctatgagggtgcgggacccgatcattcgtcgtgccgcatcgaacgctgg
ttgcagaccgccgacgaggggaacatcgccgtgacgatgcccagcacggcggcaagctac
ttccacctgctgcgccagcacgcctatgtgaactggcaccgtccgctggtggtggccaca
ccgaagtcgatgttgcgcaacaaggcggcggccagcccactgagtgacctgctggacgag
ccctggcggcccgcgctggccgatcccaccatcaccgatcccggagccgtgcggcgcgtc
ctgctgtgcgccggcaagatccgctgggacctggtggccgagcgccgcaagctcggtctg
gacgggcagatcgccatcgtctccctggagcggttgttcccgctgccgaccgccgagctc
gccgagatcctccgggcgttcccgcaggtcaacgacttccgctacgtgcaggaggagccc
gagaaccagggggcctgggaattcatggaccgcttcctgacccccgcgctctcggaggcg
ctgaataggcccttccggatgcgtccggtcacccggccccgttcgtcggcgccctcggtc
ggctcccacaccgtgcacctggcgcagcagcgctcgttgctggcggaatcgctcggccag
gactga
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