KEGG   Pteropus vampyrus (Indian flying fox): 120582906
Entry
120582906         CDS       T07511                                 
Symbol
FGFR3
Name
(RefSeq) fibroblast growth factor receptor 3 isoform X1
  KO
K05094  fibroblast growth factor receptor 3 [EC:2.7.10.1]
Organism
pgig  Pteropus vampyrus (Indian flying fox)
Pathway
pgig01521  EGFR tyrosine kinase inhibitor resistance
pgig04010  MAPK signaling pathway
pgig04014  Ras signaling pathway
pgig04015  Rap1 signaling pathway
pgig04020  Calcium signaling pathway
pgig04144  Endocytosis
pgig04151  PI3K-Akt signaling pathway
pgig04550  Signaling pathways regulating pluripotency of stem cells
pgig04810  Regulation of actin cytoskeleton
pgig05200  Pathways in cancer
pgig05206  MicroRNAs in cancer
pgig05219  Bladder cancer
pgig05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:pgig00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    120582906 (FGFR3)
   04014 Ras signaling pathway
    120582906 (FGFR3)
   04015 Rap1 signaling pathway
    120582906 (FGFR3)
   04020 Calcium signaling pathway
    120582906 (FGFR3)
   04151 PI3K-Akt signaling pathway
    120582906 (FGFR3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    120582906 (FGFR3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    120582906 (FGFR3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    120582906 (FGFR3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    120582906 (FGFR3)
   05206 MicroRNAs in cancer
    120582906 (FGFR3)
   05230 Central carbon metabolism in cancer
    120582906 (FGFR3)
  09162 Cancer: specific types
   05219 Bladder cancer
    120582906 (FGFR3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    120582906 (FGFR3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pgig01001]
    120582906 (FGFR3)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:pgig04090]
    120582906 (FGFR3)
Enzymes [BR:pgig01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     120582906 (FGFR3)
Protein kinases [BR:pgig01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   120582906 (FGFR3)
CD molecules [BR:pgig04090]
 Proteins
  120582906 (FGFR3)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase I-set Ig_3 ig Ig_2 V-set FGFR3_TM C2-set_2 ABC1 Pkinase_fungal
Other DBs
NCBI-GeneID: 120582906
NCBI-ProteinID: XP_039694240
LinkDB
Position
Unknown
AA seq 1044 aa
MGAPACALAFCVAVAVVTGAASGPPDAEQSVVRRAAEVPGPEPGQQEQLVFGSGDTVELS
CHRPAGGPSGPTVWVKDGAGLAPSDRILVGPQRLQVLNASHEDAGAYSCQLGLTRRVLCR
FSVRVTDAPSSGDDEDGEDEAEDTAGAPYWTRPERMDKQLLAVPAANTVRFRCPAAGNPA
PSISWLKDGKEFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTL
DVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGT
PYVTVLKSWISESAEADARLRLANVSERDGGEYLCRASNFIGVSEKAFWLRVHGPRAAEE
ELVAAGEAGSVYAGVLSYGVGFLLFILVVAAVTLCRLRSPPKKGLGSPTVHKVSRFPLKR
QVTVSLESNSSMNSNTPLVRIARLSSGEGPALANVSELELPADPKWELPRARLTLGKPLG
EGCFGQVVMAEAIGIDKDRATKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNII
NLLGACTQGGPLYVLVEYAAKGNLREYLRARRPPGMDYSFDTCKLPEEQLTFKDLVSCAY
QVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVK
WMAPEALFDRVYTHQSDVWSFGVLLWETFTLGGSPYPGIPVEELFKLLKEGHRMDKPANC
THDLYMVMRECWHAVPSQRPTFKQLVEDLDRILTVTSTDVSAGRATPCRGPGPGGGHSPD
CHPPARRSTWICRCPLSSTHPAARTPLAPAPRAMTPCLPTTCCPLLPPAAGACRREGPPA
CRLSPQQCERGPQPTVLLWVCCRPLGPRSPGPRPGMDGQMDRRRCFCVCMFVCVRACVHA
CVCVSRPPVQGSPRCPPCCTMTSWPPVPAAPGGPNIECKGAAPVGLLAQAPLPLTATPQG
ALGTGWALVSSECPSRACRESPLWRACHLSSTLRLGVSLTQPPPPGLPPAHPVPQRLKLR
VPEGGSLYLLSERFIPEMSVHLYK
NT seq 3135 nt   +upstreamnt  +downstreamnt
atgggcgccccggcttgcgccctcgcgttctgcgtggccgtggcggtcgtgaccggagct
gcctcggggcccccggacgcagagcagagcgtcgtgcggagagcggcagaggtcccggga
cctgagccgggccagcaggagcagctggtcttcggcagtggtgacactgtggagctgagc
tgccacaggcccgccggcggtccctcggggcctaccgtctgggttaaggatggggcaggg
ctggcaccctccgaccgcatcctggtgggaccccagcggctgcaggtgctgaatgcctcc
cacgaggacgccggggcctacagctgccagctggggctcacccggcgtgttctgtgccgc
ttcagcgtgcgtgtgacagacgccccgtcctcgggagatgacgaagatggggaggacgaa
gcggaagacacagcaggggccccttactggacacggcccgagcggatggacaagcagctg
ctggctgtgccggccgccaacaccgtccgcttccgctgcccggcggccggcaaccccgcc
ccatctatctcctggctgaaggacggcaaggagttccggggcgagcaccgcatcgggggc
atcaagctgcgtcaccagcagtggagcctggtcatggagagcgtggtgccctccgaccgc
ggcaactacacgtgcgtcgtggagaacaagttcggcagcatccggcagacgtacaccctg
gacgtgctggagcgctccccgcaccggcccatcctccaggcggggctgccggccaaccag
acggcggtgctgggcagcgacgtggagttccactgcaaggtgtacagcgacgcgcagccc
cacatccagtggctcaagcatgtcgaggtgaatggcagcaaagtcgggcccgacggcacg
ccctacgtcactgtgctcaagtcctggatcagtgagagtgcggaggccgacgcgcgcctc
cgcctggccaatgtgtccgagcgtgacgggggcgagtacctctgtcgagcctccaatttc
ataggcgtgtctgagaaggccttttggctgcgcgttcacgggccccgagcagctgaggag
gagctggtggcggctggtgaggctggcagcgtgtacgcaggcgtcctcagctacggggtg
gggttcctgctcttcatcctggtggtggccgccgtgacgctctgccgcctgcggagcccc
cccaagaagggcctgggctcgcccaccgtgcacaaggtctcccgcttcccgctcaagcga
caggtaacagtgtccttggagtccaactcgtccatgaactccaacacgccgctggtgcgc
atcgccaggctgtcctcgggggagggccctgcgctggccaacgtctcggagctggagctg
cccgccgaccccaagtgggagctgccccgggcccggctgaccctaggcaagcctctcggc
gagggctgcttcggccaggtggtcatggcagaggccatcggcatcgacaaggaccgggcc
actaagcccgtcacggtggctgtgaagatgctgaaagacgacgccaccgacaaagacctc
tcggacctggtgtcagagatggagatgatgaagatgatcgggaagcataagaacatcatc
aacctgctgggcgcctgcacgcagggcgggcccctgtatgtgctggtggaatacgcggcc
aagggcaacctgcgggagtacctgcgggcccggcggcccccgggcatggactactccttc
gacacctgtaagctgccggaggagcagctcaccttcaaggacctggtgtcctgtgcctac
caggtggcgcggggcatggagtacctggcctcgaaaaagtgcatccacagggacctggcg
gcccgcaacgtactggtgaccgaggacaacgtgatgaagatcgcggactttggcctggcc
cgtgacgtgcacaacctcgattactacaaaaagaccaccaacgggcggctgcctgtgaag
tggatggcacccgaggccttgtttgaccgcgtctacacccaccagagcgacgtctggtcc
ttcggggtcctgctgtgggagaccttcaccctgggcggctccccgtatcccggcatcccc
gtggaggagcttttcaagctgctgaaggaaggccaccgcatggacaagccagccaactgc
actcacgacctgtacatggtcatgcgggagtgttggcacgctgtgccctcgcagaggccc
accttcaagcagctggtggaggacctggaccgaatccttactgtgacatccaccgacgta
agtgctggccgtgccacaccctgccgtgggccgggccctgggggagggcacagccctgac
tgccacccacctgcccgcaggagtacctggatctgtcggtgccctttgagcagtactcac
ccggcggccaggacacccctagctccagctcctcgggcgatgactccgtgtttgcccacg
acctgctgccccctgctccccccagcagcgggggcctgcagacgtgaagggccaccagcc
tgcaggctgagcccccagcaatgtgagcgtggaccccagcctaccgtgctgctgtgggtg
tgctgtcgaccactggggcccaggagcccaggcccgagacctggcatggatggacagatg
gacagacgacgttgcttctgtgtgtgcatgtttgtgtgcgtgcgtgcgtgcgtgcatgcg
tgtgtgtgtgtctcgaggcccccggtgcaggggtccccgaggtgcccgccctgctgtaca
atgacctcctggccacctgtgccagcagcaccagggggaccaaatatagaatgtaagggg
gctgctccagtggggctcctcgcccaggctcccttgcccctcactgccaccccacaggga
gcattggggacaggctgggctctggtgtcctccgagtgccccagccgagcctgcagggaa
agccccctgtggcgtgcctgccacctgagcagcaccttgcgcctgggggtgagtctcaca
cagcccccacctccaggccttccccctgcccaccctgtccctcagagactgaaattacgg
gtacctgaaggcgggagcctttaccttctatcggagaggtttattccagagatgagtgta
catttatataaatag

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