Pteropus vampyrus (Indian flying fox): 120587528 Help Entry 120587528         CDS       T07511                                  Symbol CASP8 Name (RefSeq) caspase-8   KO K04398   caspase 8 [EC:3.4.22.61] Organism pgig  Pteropus vampyrus (Indian flying fox) Pathway pgig01524   Platinum drug resistance pgig04115   p53 signaling pathway pgig04210   Apoptosis pgig04215   Apoptosis - multiple species pgig04217   Necroptosis pgig04620   Toll-like receptor signaling pathway pgig04621   NOD-like receptor signaling pathway pgig04622   RIG-I-like receptor signaling pathway pgig04623   Cytosolic DNA-sensing pathway pgig04625   C-type lectin receptor signaling pathway pgig04657   IL-17 signaling pathway pgig04668   TNF signaling pathway pgig04932   Non-alcoholic fatty liver disease pgig04936   Alcoholic liver disease pgig05010   Alzheimer disease pgig05016   Huntington disease pgig05022   Pathways of neurodegeneration - multiple diseases pgig05132   Salmonella infection pgig05134   Legionellosis pgig05142   Chagas disease pgig05145   Toxoplasmosis pgig05152   Tuberculosis pgig05160   Hepatitis C pgig05161   Hepatitis B pgig05162   Measles pgig05163   Human cytomegalovirus infection pgig05164   Influenza A pgig05165   Human papillomavirus infection pgig05167   Kaposi sarcoma-associated herpesvirus infection pgig05168   Herpes simplex virus 1 infection pgig05169   Epstein-Barr virus infection pgig05170   Human immunodeficiency virus 1 infection pgig05200   Pathways in cancer pgig05203   Viral carcinogenesis pgig05416   Viral myocarditis pgig05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:pgig00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     120587528 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     120587528 (CASP8)    04215 Apoptosis - multiple species     120587528 (CASP8)    04217 Necroptosis     120587528 (CASP8)    04115 p53 signaling pathway     120587528 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     120587528 (CASP8)    04621 NOD-like receptor signaling pathway     120587528 (CASP8)    04622 RIG-I-like receptor signaling pathway     120587528 (CASP8)    04623 Cytosolic DNA-sensing pathway     120587528 (CASP8)    04625 C-type lectin receptor signaling pathway     120587528 (CASP8)    04657 IL-17 signaling pathway     120587528 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     120587528 (CASP8)    05203 Viral carcinogenesis     120587528 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     120587528 (CASP8)    05161 Hepatitis B     120587528 (CASP8)    05160 Hepatitis C     120587528 (CASP8)    05164 Influenza A     120587528 (CASP8)    05162 Measles     120587528 (CASP8)    05168 Herpes simplex virus 1 infection     120587528 (CASP8)    05163 Human cytomegalovirus infection     120587528 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     120587528 (CASP8)    05169 Epstein-Barr virus infection     120587528 (CASP8)    05165 Human papillomavirus infection     120587528 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     120587528 (CASP8)    05134 Legionellosis     120587528 (CASP8)    05152 Tuberculosis     120587528 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     120587528 (CASP8)    05142 Chagas disease     120587528 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     120587528 (CASP8)    05016 Huntington disease     120587528 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     120587528 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     120587528 (CASP8)    05416 Viral myocarditis     120587528 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     120587528 (CASP8)    04932 Non-alcoholic fatty liver disease     120587528 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     120587528 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:pgig01002]     120587528 (CASP8) Enzymes [BR:pgig01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      120587528 (CASP8) Peptidases and inhibitors [BR:pgig01002]  Cysteine peptidases   Family C14: caspase family    120587528 (CASP8) SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED COG6_N PYRIN YeeD Motif Other DBs NCBI-GeneID:  120587528 NCBI-ProteinID:  XP_039700363 LinkDB All DBs Position Unknown AA seq 484 aa AA seqDB search MSFNSCLYDIGENLGSDELASLKFLSLDYIPQRKQEPIKDALTLFQRLLEKRMLEESNLS FLKELLFRINRLDLLVNHLDTSGEEMKKELQIPGKAQISAYRVMLFQISEDVSKPELKAF KFLLSQEIAKCKLEDDMTLLDIFIEMEKRLILGKRNLDTLKRICDQVNKSLLKKISDYEE LSRDVSQSCAGELSLEMLSMSDSPGEQDCESQEQGSESEDTESQQTSDKVYRMKSKPRGY CVIFNNYDFSEARKAVPKLHSIKDRNGTDLDAGALSETFKDLHFEINTFKNCTAKEICDV LKSYQSRNHNNKDCFICCILSHGDKGIIYGCDGQEVPIYELTSYFTGSNCPSLLDKPKIF FIQACQGDNYQRGIPVETDSEEKETYLEMDSSFQKRYIPDEADFLLGMATVNNCVSYRNP MEGTWYIQSLCQSLREKCPRGEDILTILTDVNFEVSRKDDKKNMGKQMPQPTFTLRKKLF FPLN NT seq 1455 nt NT seq  +upstreamnt  +downstreamnt atgagtttcaacagttgtctctatgatattggagaaaatctgggcagtgatgagctggcc tccctcaagttcctgagcctggactacatcccacaaaggaagcaggaacccatcaaggat gccttaacattgttccagagactcctggaaaagagaatgttggaggaaagcaacttgtcc ttcttgaaggagctgctattccgaattaatagactggatttgctggtcaaccacctagac accagcggagaagagatgaagaaggagctgcagataccgggcaaggctcagatctctgcc tacagggtcatgctttttcagatttcggaagacgtaagcaaaccggaattgaaggccttt aagtttcttttgagccaggagatcgccaaatgtaaactggaagatgacatgaccttgctt gatattttcatagagatggagaagaggcttatacttgggaaaagaaatctggacactctg aaaagaatctgtgaccaagtcaacaagagcctgctgaagaaaatcagtgattatgaagaa ttaagcagagatgtgtctcagtcgtgtgcaggggagttgtcattggagatgctatcaatg tcggactctcccggagaacaggactgtgaatcacaagaacagggcagtgagtcagaagac accgagtcacaacagacatcggacaaagtttaccgaatgaaaagcaagcctcgtgggtac tgtgtgatatttaacaattatgattttagcgaagcacggaaggctgtgcccaaacttcac agcatcaaggatagaaatggaacagacttggatgcaggggctttgagtgaaacctttaaa gaccttcattttgagataaatactttcaaaaactgcacagcaaaggaaatctgtgatgtt ctgaaatcctatcaaagcagaaaccacaataacaaggactgcttcatctgttgcatcctc tcccatggagacaagggcatcatctatggctgtgatgggcaggaagtccctatctatgag ctgacttcttacttcactggttcaaattgcccttccctcctagacaaacccaaaatcttt tttattcaggcttgtcaaggggataactaccagagaggtatacctgttgagactgactca gaagagaaggaaacctatttagaaatggattcatcatttcagaagagatatatccctgat gaggccgactttctgctagggatggccactgtgaacaactgtgtttcctaccgaaacccc atggaggggacctggtatattcagtcactctgtcagagcctgagagaaaaatgtcctagg ggtgaagatattcttaccatcctcactgatgtgaactttgaagtgagcagaaaggatgac aagaaaaatatggggaagcagatgccacaacctaccttcaccctgagaaaaaaactcttt ttccctctgaattga

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