Pteropus vampyrus (Indian flying fox): 120598839
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Entry
120598839 CDS
T07511
Symbol
BACE2
Name
(RefSeq) beta-secretase 2 isoform X1
KO
K07747
beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:
3.4.23.45
]
Organism
pgig
Pteropus vampyrus (Indian flying fox)
Pathway
pgig05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
pgig00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
120598839 (BACE2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
pgig01002
]
120598839 (BACE2)
Enzymes [BR:
pgig01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.45 memapsin 1
120598839 (BACE2)
Peptidases and inhibitors [BR:
pgig01002
]
Aspartic peptidases
Family A1: pepsin family
120598839 (BACE2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
Motif
Other DBs
NCBI-GeneID:
120598839
NCBI-ProteinID:
XP_039713844
LinkDB
All DBs
Position
Unknown
AA seq
514 aa
AA seq
DB search
MGALARALLPPLLAQWLLCAAAALASAPFTLPLRVAAATGRGAAPTPGPGPPTEPRADGL
AFALEPAAGAANFLAMVDNLQGDSGRGYYLEVLIGTPPQKLQILVDTGSSNFAVAGAPHS
YTDSYFDTKRSSTYRPKGFDVTVKYTQGSWAGLVGEDVVTIPKGFNGSFVVNIATIFESE
NFFLPGIKWNGILGLAYAALAKPSSSLETFFDSLVAQAKIPNVFSMQTCGAGLPVAGSGT
NGGSLVLGGIEPSLYTGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDS
GTTLLRLPQKVFNAVVEAVVRTSLIPEFSDGFWTGSQLACWTNSEAPWSYFPKISIYLRD
ENSSRSFRITLLPQLYIQPMMGAGLNYECYRFGISPSTNALVLGATVMEGFYVVFDRARK
RVGFAASPCAEIAGAPVSEISGPFSTDDIASNCVPALPLNEPVLWVVSYTLMSVCGVILL
ILIILLLLPSRCRHLPRDPEVVSDESSLVRHRWK
NT seq
1545 nt
NT seq
+upstream
nt +downstream
nt
atgggcgcgctggcccgggcgctgctgccgccgctgctggcccagtggctcctgtgcgcc
gccgcggcgctggcctcggcgcccttcacgctgcccctccgcgtggccgcggccacaggc
cgcggggctgcgcccacccccgggcccgggccccccaccgagccccgcgccgacggcctg
gcgttcgccctggagcccgccgcgggcgcggccaacttcttggccatggtggacaacctg
cagggggactccggccgcggctactacctggaggtgctgatcgggacccccccgcagaag
ctgcagattctcgtcgacactggcagcagcaacttcgccgtggccggagccccgcattct
tacacagactcgtacttcgacacgaagaggtccagcacgtaccggccgaagggcttcgac
gtcaccgtcaagtacacgcaggggagctgggccggcctggtgggggaggacgtcgtcacc
atcccaaaaggcttcaatggttctttcgtggtcaacatcgccacgatcttcgagtcggag
aatttcttcctgcctgggattaaatggaacgggattctaggacttgcttatgccgccctg
gctaagccatcgagttctctggagacgttcttcgattccctcgtggcacaagcgaaaatc
cccaacgtcttctccatgcagacgtgtggggcgggcttgccagtggctggatctggcacc
aatggaggcagtctggtcctgggtggcattgaaccgagtttgtacacaggagacatctgg
tataccccgattaaggaggagtggtattatcagatagaaatcctcaagctggagatcgga
ggccagagtcttaacctggactgcagagagtacaacgcggacaaggccatcgtggacagc
ggcaccacgctgctgcgtctgccccagaaggtgttcaatgcggtggtcgaagccgtggtc
cgcacgtctctgattccagaattctctgacggcttctggactgggtcccagctggcgtgc
tggacgaattccgaagcgccttggtcttacttccctaaaatctccatctacctgagagac
gagaactccagcaggtccttccgcataactctcctgcctcagctttacattcagcccatg
atgggggctggcctgaattacgagtgctaccgattcggcatttcgccttccacgaacgcg
ctggtgctcggtgccaccgtgatggagggcttctacgtggtctttgacagagcccggaag
agggtgggctttgcagccagcccctgtgcagaaatcgcaggtgctccggtgtctgaaatc
tctgggcctttctcaacagacgacatagccagcaactgtgtccccgccctgcctttgaac
gagcccgtgttgtgggtcgtctcctacacgctcatgagcgtgtgtggggtcatcctcctc
atcttaatcatcctgcttctcctcccgtcccggtgtcggcacctcccacgagaccccgag
gtcgtcagcgatgagtcctctctcgtccggcaccgctggaagtga
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