Pteropus vampyrus (Indian flying fox): 120601871
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Entry
120601871 CDS
T07511
Symbol
ACACB
Name
(RefSeq) acetyl-CoA carboxylase 2 isoform X1
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
pgig
Pteropus vampyrus (Indian flying fox)
Pathway
pgig00061
Fatty acid biosynthesis
pgig00620
Pyruvate metabolism
pgig00640
Propanoate metabolism
pgig01100
Metabolic pathways
pgig04152
AMPK signaling pathway
pgig04910
Insulin signaling pathway
pgig04920
Adipocytokine signaling pathway
pgig04922
Glucagon signaling pathway
pgig04931
Insulin resistance
pgig04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
pgig00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
120601871 (ACACB)
00640 Propanoate metabolism
120601871 (ACACB)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
120601871 (ACACB)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
120601871 (ACACB)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
120601871 (ACACB)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
120601871 (ACACB)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
120601871 (ACACB)
04931 Insulin resistance
120601871 (ACACB)
Enzymes [BR:
pgig01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
120601871 (ACACB)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
120601871 (ACACB)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
120601871 (ACACB)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
120601871
NCBI-ProteinID:
XP_039717703
LinkDB
All DBs
Position
Unknown
AA seq
2451 aa
AA seq
DB search
MILVFLSCLIFSYLTFSLLKIWGKMTDIKAVREKSEANFVPSQEPFPASDSSEEPLQKNG
DSSSLPETPNQAELASHKGPKDACQQRTSKPPLHRNPPRNSVPSSDDSPANGTGTQGLEA
LDTSGLSSPARSQGQRARPLSAEDKKQAHIKRQLMTNFILGSFDDNSSDEDPGPGSFGES
SRRGSRASLGALSLEAALTSGDSETPAPTIRPSMSGLHLVKRGREQRKVDLQRDFTVASP
AEFVTRFGGNQVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKAN
AEYIKMADQYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKY
KIAFLGPPSEAMWALGDKIASTIVAQTLQIPTLPWSGSGLTVKWEKDGLQQEKTISVPED
IYNQGCVKDVDEGLEAAEKIGFPLMIKASEGGGGKGIRKVESAEDFPVLFRQVQSEIPGS
PIFLMKLAQRARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIAKPAVFEFM
EQCAVLLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQI
AMGVPLHRLKDIRLLYGESPWGVTPISFETPSHPPLVRGHVIAARITSENPDEGFKPSSG
TVQELNFRSSKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIR
GDFRTTVEYLINLLETESFQNNDIDTGWLDHLIAEKVQAEKPDIMLAVVCGALNVADAKF
RTCMTDFLHSLERGQVLPADSLLNTVDVELIYGGIKYILKVARQSLTMFVLIMNGCHIEI
DAHRLNDGGLLLSYNGSSYTTYMKEEINSYWITIGNKMCVFEKENDPTVLRSPSAGKLVQ
YMVEDGGHVEAGDSYAEMEVMKMIMALNVQESGHVKYIKHPGAVLEAGCVVAKLELDDPS
KVRPAEPFTGELPSQQTLPIIGEKLHQVFHSVLENLTNIMSGYCLPEPIFSIKLKEWVQK
LMATLRHPSLPLLELQEIMTSVSGRIPASVEKSVRRVMAQYASNITSVLCQFPSQQIATI
LDCHAATLQRKADREVFFMNTQSIVQLVQRYRSGTPGYMKAVVLDLLRRYLQVEHHFQQA
HYDKCVINLREQLKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSEELTSILN
DLTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCPDNLKKLI
LSETTIFDVLPTFFYHTNKVVCMASLEVYVRRAYIAYELNSLQHRQLPDGTCVVEFQFML
PSSHPNRIAMPINVTNPDLLRHSTELFMDSGFSPLCQRLGAMVAFRRFEEFTRNFDEVIS
CFANVLTDTPIFSKAQTSLYSEDDGKNLREEPIHILNVAIQYADHLEDEKLVPILRTFVQ
SKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRMRN
FDLKAVPCANHKMHLYVGAAKVKEGAEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGER
LLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPYKIEESVRSMVMRYGSRLWKLRV
LQAEVKINIRQTTTGGVIPIRLFLTNESGYYLDISLYKEVTDPRSGNIMFHSFGNKQGPQ
HGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKLWGSPDKYPQDILTYTE
LVLDSQGQLVEMNRLPGGNEVGMVAFRMKFKTPEYPEGRDVIVISNDITFRIGSFGLRED
LLYLRASEMARAEGIPKIYLAANSGARIGLAEEIKHMFQVAWVSPEDPHKGFKYLYLTPQ
DYTKISSLNSVHCKHIEEEGESRYVITDIIGKDDELGVENLRGSGTIAGESSLAYEEIIT
ISLVTCRALGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGRDVYTSNNQLGGVQIMY
YNGISHVTVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSRASYDPRW
MLAGRPHPTLKGSWQSGFFDHGSFREILAPWAQTVVTGRARLGGIPVGVISVETRTVEVA
VPADPANLDSEAKIIQQAGQVWFPDSAYKTAQVIKDFNREKLPLMIFANWRGFSGGMKDM
YDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVLDSTINPLCIEMYADKESRGS
VLEPEGTVEIKFRKKDLLKAMRRIDPTYKKLVEQLGMSELSDKDRKDLESQLKAREDLLL
PIYHQVAVQFADLHDTPGRMLEKGVISDILEWKTSRSFLYWRLRRLLLEDQVKQEILQIS
SELSHVHIQSMLRRWFMETEGAVKAYLWDNNQMVVQWLEQHWQVEDGLHSTIRENIKYLK
RDSALKTIRGLVQENPEVALDCMMHMSQHISPAERAQVAHLLSTMDSPAST
NT seq
7356 nt
NT seq
+upstream
nt +downstream
nt
atgatcctggtttttttatcttgtctgatattctcttacctcaccttttccttgttaaaa
atctgggggaaaatgacggacatcaaggcagtcagagagaaatcagaggcaaacttcgtc
ccaagtcaggagccctttccagcctccgacagctcagaagagccactgcagaaaaatggc
gacagcagctctctgccagagactcctaaccaggctgagctggcctctcacaaaggtccc
aaagacgcttgtcagcaaagaacctccaaaccacccctacatcggaatcccccaagaaat
tctgttccctccagtgatgactccccagccaatggaacagggacccaaggccttgaggct
ctggataccagtggtctgtcctcaccagccaggtcccagggccagcgagccagacccctt
tctgcagaagacaagaagcaggcacacatcaagaggcagctgatgaccaacttcatcctg
ggctcctttgatgacaactcctctgatgaggaccctggccctggctcattcggagaatct
tcccgcaggggcagccgggccagcctgggagccctgtccctggaggctgctctgacatca
ggcgactccgagacccctgcccccactataagacccagtatgtcgggactccacctggtg
aagaggggccgagaacagaggaaggtggatctacagagagacttcaccgtagcttctcca
gccgagtttgtcacacgctttggggggaatcaggtcattgagaaggtgctcatcgccaac
aatggcatcgctgccgtgaagtgtatgcgttccatccgcaggtggtcctacgagatgttt
cgaaatgaacgggccattcggtttgtagtcatggtgactccagaggacctcaaggccaat
gcagagtatatcaagatggcagatcagtacgtccctgtcccaggagggcccaacaacaac
aattatgccaacgtggagctgattgtggacattgccaagagaatccccgtgcaggcggtg
tgggctggctggggccatgcttctgaaaaccccaaacttccggagctcctgtgcaagtac
aagattgctttcttaggccctcccagtgaggccatgtgggccctgggagataagatcgcc
tctaccatcgtggcccagacgctgcagattcccacactgccctggagtggaagtggtctg
acagtgaagtgggaaaaagatggtctgcagcaggaaaaaacaatcagtgtcccagaagac
atttacaaccagggttgtgtgaaagacgtagatgaaggcttggaggcagcagaaaaaatt
ggttttccattgatgatcaaagcttctgaaggcggtggagggaaaggaatccgaaaagtg
gagagtgctgaggacttcccagtcctcttcagacaagtgcagagcgagatcccgggctcc
cccatctttctcatgaagctggcccagcgcgcccgtcacctggaggtccagatcctcgca
gaccagtatgggaacgccgtgtccctgtttgggcgagactgctccatccagcggcgacat
cagaaaatcatcgaggaggcacctgccaccatcgctaaacctgctgtgttcgagttcatg
gagcagtgtgctgtcctcttggccaagacggtgggctacgtgagcgcaggcacagttgaa
tatctctacagccaggatggcagcttccacttcttggagctgaatccccgcctgcaggtg
gaacacccctgcacagaaatgatcgctgatgtgaatctgccggctgcccagctacagatt
gcaatgggtgtgccactgcaccggctgaaggatatccgacttttgtacggagagtcacca
tggggggtgacgcctatttcttttgaaactccttcccaccctccgctcgtccgaggccac
gtcattgcagccagaatcaccagtgaaaacccagatgaggggtttaagccgagctctgga
acagtccaggaattgaattttcgcagcagcaagaatgtgtggggttatttcagcgtggct
gctgctggtggcttacatgagtttgctgattctcagtttggtcactgtttctcttgggga
gagaaccgggaagaggccatttcgaacatggtggtggctttgaaggaactgtccatccga
ggtgacttcagaacgactgtggaatatctcattaacctcctggagaccgagagcttccag
aacaacgacatcgacactgggtggctagatcatctcatcgctgagaaagtgcaggccgag
aagccagatatcatgcttgcggtggtgtgcggagccttgaacgtggctgatgcgaagttc
agaacctgcatgacagattttttacactctctggaaaggggccaggtcctccctgcggat
tccctcctgaacactgtggatgtggaattaatttacggaggcattaaatacattctcaag
gtggcccggcagtctctgaccatgtttgtcctcatcatgaatggctgtcacattgagatc
gatgcccaccggctaaacgatggcgggcttttgctgtcctacaatggcagcagctacaca
acctacatgaaagaagagatcaacagttactggattaccattggcaacaagatgtgtgta
tttgagaaggagaatgatcccacggtcctgagatccccctcagctgggaagctggttcag
tacatggtggaggatgggggccacgtggaggctggggacagctatgctgagatggaggtg
atgaagatgatcatggccctgaatgtgcaggaaagtggccatgtgaagtatatcaagcac
ccgggagccgtgctggaagcaggctgtgtggtggccaagctggagcttgatgacccttct
aaagtgcgcccggctgagccgttcacaggagagctcccttcccagcaaactctgcccatc
attggggagaagctgcaccaggtcttccacagcgtcttggagaacctgactaacatcatg
agcggctactgtctgccagagcctatttttagcataaagctgaaggagtgggtgcagaag
ctcatggcgactctccgacacccatcactgccgctgctagagctgcaagagatcatgacc
agcgtgtcaggccgcatccctgcctccgtggagaagtcggtccgcagggtgatggcccag
tatgccagcaacatcacctcagtgctgtgccagttccccagccagcagatagccaccatc
ctggactgccacgcagccaccctgcaacggaaggctgaccgggaggtcttctttatgaac
acccagagcatcgtgcaattggttcagagataccgtagtgggacccctggctacatgaag
gcagtggtgttggatcttctgcgaagatatttacaagttgagcaccatttccaacaagcc
cactacgacaagtgtgtgataaacctcagggaacagctgaagccagatatgtcccaggtg
ctggactgcatcttctctcatgcgcaggtggctaagaagaaccagctggtgatcatgttg
attgatgagctctgtggcccagacccttccttgtcagaggaactgacctccatcctcaat
gacctcactcagctgagcaagagtgagcattgcaaagtggccctcagagccagacagatc
ctgattgcctcccacctcccctcctatgagctgaggcacaaccaggtggagtccattttc
ctgtctgccattgacatgtacggccaccagttctgcccagacaacctcaagaaattaata
ctctcagaaacgaccatatttgatgtcctgcccactttcttctatcacactaacaaagtg
gtctgcatggcatctttggaggtttatgtgcggagggcctacatcgcctatgagttaaac
agcctgcagcaccggcagctcccggatggcacctgtgtggtggaattccagttcatgctg
ccctcctcccacccaaaccggatagccatgcccatcaatgtcaccaaccccgacctgctg
aggcacagcaccgagctcttcatggacagtggcttctcccctctgtgccagcggctgggg
gccatggtcgccttcaggagattcgaggaattcaccaggaacttcgacgaagtcatctcc
tgctttgccaatgtgctcacagacactcccatcttcagcaaggcccaaacttctttgtac
tctgaggatgatggcaagaacctgagagaagagccaatccacatcttgaacgtggccatc
cagtatgcggaccacctggaggacgagaagctggtaccgattttgcggacgttcgtacag
tccaagaaaaacatccttgtggattacggactccgaagaatcacgttcctgatcgcccaa
gagaaagaatttcccaagtttttcaccttcagagcaagagatgagtttgcagaagatcgc
atttaccgtcacctggagcccgccctggccttccagctggagcttagccggatgcgcaat
tttgatctgaaggccgtgccctgtgccaaccacaagatgcatctttacgtgggcgctgcc
aaggtgaaggaaggtgcagaagtgacagaccacaggttcttcatccgcgccatcatcagg
cactcagacctgattacaaaggaagcctccttcgagtacctgcagaacgagggtgagcgg
ctgctcctggaggccatggacgagctggaggtggcgttcaacaacaccagcgtgcgcact
gactgtaaccacatcttcctcaacttcgtgcccactgtcatcatggacccctataagatt
gaggagtcggtgcgttccatggttatgcgctatggcagccggttgtggaaactccgtgtg
ctacaggctgaggtcaagatcaacattcgccagaccaccaccggaggtgtcattcccatc
cgcctgttcctcacgaatgagtcaggctactacctggatatcagcctctacaaagaagtc
accgaccccagatctggaaatatcatgtttcactcctttggcaacaaacaagggcctcag
cacggaatgctgatcaacactccctatgtcaccaaggatctgcttcaggccaagcgattc
caggcccagtccttgggaaccacctatgtgtacgacttcccagaaatgttcaggcaggct
ctctttaaactgtggggctccccagacaagtacccccaagatatcctgacgtacactgaa
ctcgtcctggactctcagggccagctggtggaaatgaaccgacttcctggaggaaatgag
gtgggcatggtggccttcagaatgaagtttaagaccccagagtatccagaagggcgggac
gtgatcgtcattagcaatgatatcaccttccgcatcggatcctttggcctacgagaagac
cttctgtacctgcgggcctctgagatggcccgggcagagggcatccccaaaatctacctc
gcagccaacagtggggcccgtatcggtcttgcggaggaaatcaaacacatgttccaggtg
gcttgggtgagcccagaagacccccacaaaggatttaaatacctgtacctgacccctcaa
gactacaccaaaatcagctccctgaactccgtccattgtaaacacatagaagaagaagga
gaatccaggtatgtcatcacagatatcattgggaaggatgatgaactgggcgtggagaac
ctgcggggttcaggcacaattgctggggagtcctccttggcttacgaagagattatcacc
attagcttggtgacctgccgagcccttgggatcggggcctacttggtgaggctgggccag
cgagtgatccaagtggaaaactcccacatcatcttgacaggagccagtgctctcaacaag
gtcttaggcagagatgtttacacatccaacaaccagctgggtggcgtgcagatcatgtat
tacaatggcatctcccacgtcaccgtgccggacgacttcgagggcgtttataccatcctg
gagtggctgtcctatatgccaaaggataatcacagtccagtccctatcatcacacccact
gaccctattgacagagaaatcgaattcctgccatccagagcttcctacgacccccggtgg
atgcttgcaggaaggcctcacccaactctaaagggatcctggcagagtggattcttcgac
cacggcagtttcagagaaatcctggcaccctgggcccagactgtggtgacgggacgagca
aggcttggggggatccctgttggagtaatttctgtggagacacggacagtggaggtggcg
gtgcccgcggaccctgccaacctggattctgaggccaagataatccagcaggcaggccag
gtgtggttcccggactcagcctacaaaacggcccaggtcatcaaggatttcaaccgggag
aagttgcccctgatgatcttcgctaactggagaggtttctctggtggtatgaaagacatg
tacgaccaggtgctgaagtttggagcctacatcgtggatggcctcaggcaatacaaacag
ccaatcctcatctacatcccaccctatgctgagctcagaggaggctcctgggtggtcctg
gactccaccatcaaccccctgtgcatagaaatgtatgcggacaaagaaagcagggggagt
gttctggagccagagggaacagtggagattaagttccgaaagaaagacctgttaaaggcc
atgagaaggatcgacccgacttacaagaagcttgtggaacagctaggaatgtccgagctc
tccgacaaggaccgcaaggacctggagagccagctgaaggcccgggaggacctgctactt
cccatataccaccaggtggcggtgcagttcgccgacctccacgatacgcctggcaggatg
ctggagaaaggcgtcatctctgacattctggaatggaagacttcaagatccttcctgtac
tggcgcctgcgccgcctcctgctggaggatcaggtcaagcaggagatcctgcagatcagc
agcgagctgagccatgtgcacatccagtccatgctgcgccgctggttcatggagacagag
ggggccgtcaaggcctacctgtgggacaacaatcagatggtggtgcagtggctggagcag
cactggcaggtggaggatggcctgcactccaccatccgagaaaacatcaagtacctgaag
cgagactctgcccttaagaccatccgaggcctggtccaggaaaaccctgaggtagccctg
gactgcatgatgcacatgagccagcacatcagcccggctgagcgggcccaagtcgctcac
ctcctgtccaccatggacagtccggcctccacctga
DBGET
integrated database retrieval system
