Pteropus vampyrus (Indian flying fox): 120603562
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Entry
120603562 CDS
T07511
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
pgig
Pteropus vampyrus (Indian flying fox)
Pathway
pgig04120
Ubiquitin mediated proteolysis
pgig04144
Endocytosis
pgig04330
Notch signaling pathway
pgig04668
TNF signaling pathway
pgig04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
pgig00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
120603562 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
120603562 (ITCH)
04668 TNF signaling pathway
120603562 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
120603562 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
120603562 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pgig04131
]
120603562 (ITCH)
04121 Ubiquitin system [BR:
pgig04121
]
120603562 (ITCH)
Enzymes [BR:
pgig01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
120603562 (ITCH)
Membrane trafficking [BR:
pgig04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
120603562 (ITCH)
Ubiquitin system [BR:
pgig04121
]
Ubiquitin ligases (E3)
HECT type E3
120603562 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
120603562
NCBI-ProteinID:
XP_039720040
LinkDB
All DBs
Position
Unknown
AA seq
862 aa
AA seq
DB search
MSDSGLELDSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVAVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIYETLKSNNMKLEEVVVTL
QLVGDKEPTETIGDLSVCLDGLQLETEVVTNGETTCSESASQNDDGSRPKDETRVNTNGS
DDPEDAGPGENRSVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTNTNSNTSEGATSGLIIPLTISGGSGPRPLNPVPQAPLPPGWEQRMDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKFQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggattagagcttgattcaatgggtagcctgaccatgaaatcacaactt
cagatcactgtcatttcagcaaaacttaaagaaaataaaaagaattggtttggaccaagt
ccttatgtggaagttgcagtagatggacagtcaaagaagacagaaaaatgcaacaatacg
aacagtcccaaatggaagcaaccccttacagttattgtcactcctgtaagtaaattacat
tttcgtgtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctgcatta
gatatctatgaaacattaaagtcaaacaatatgaaacttgaggaagtagttgtgacttta
cagcttgtaggtgacaaagagccaacagaaacaataggagacttgtcagtttgtcttgat
gggctacagttagagactgaagttgttaccaacggtgaaacgacatgttcagaaagtgct
tcacagaatgatgatggttccagacctaaggatgaaacaagagtgaacacaaatggatca
gatgaccctgaggatgcagggcctggtgaaaataggagcgtcaatgggaataattctcca
tcactctcaaatggcggttttaaaccttctaggcctccaagaccttcacgaccacctcca
cctaccccacgtagaccagcatctgtcaatggttcaccttctgccacttctgaaagtgat
ggatctagtacaggttctctgccgccaacaaatacaaattcaaatacatctgaaggagct
acgtctggattaataattcctcttactatatctggaggctcaggccccaggccattaaat
cctgtacctcaagctcccctaccacctggttgggagcagagaatggaccaacatgggcga
gtttactatgtagatcatattgaaaaaagaacaacgtgggatagaccagaacctctacct
cctggctgggaacggcgagtcgacaacatgggacgtatttattatgttgaccatttcaca
agaacaacaacatggcagaggccaacattggaatctgtccggaactatgaacagtggcag
ctccagcgtagtcaacttcaaggagcaatgcagcagtttaatcagagattcatttatggg
aatcaagatttgtttgctacatcacaaaataaagaatttgatcccttgggtcccctgcca
cctggatgggagaagagaacggacagcaatggaagagtatattttgtcaaccacaacact
cgtattacacaatgggaggaccccaggagtcaaggtcagttaaatgaaaagcccttacct
gaaggttgggaaatgagattcacagtggatggaattccatattttgtggaccacaataga
agaacaaccacctatatagatccccgcactggaaaatctgccctagacaatggaccccag
atagcctatgtacgagacttcaaggcaaagtttcagtatttccggttctggtgtcagcaa
ctggccatgccacaacacataaagattacagtgacaaggaaaacattgtttgaggattct
tttcagcagataatgagcttcagtccccaagatctccgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagaatggttctttcttttgtca
catgaggtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataactactgc
ttgcagataaaccccgcttcttacatcaatccagatcacctgaaatattttcgatttatt
ggaaggtttattgccatggctctgttccatgggaaattcatagacacaggcttttctttg
ccattctataagcgtatcttgaacaaaccagttggactcaaggatttagaatctattgat
ccagaattttacaattctctcatctgggttaaagaaaacaacattgaggaatgtggattg
gaaatgtacttctctgttgataaagaaattttgggtgaaatcaagagtcatgatttgaaa
cccaatggtggcaatattcttgtaacagaagaaaataaagaagaatatatcagaatggta
gccgaatggaggttgtctcgaggtgttgaagaacagacgcaagctttctttgagggcttt
aatgaaattcttccccagcagtatttgcagtactttgatgcaaaggaattagaggtcctt
ttatgtggaatgcaagagattgatctaaatgattggcaaagacatgccatttaccgtcat
tacactaggacaagtaaacaaatcatgtggttttggcagtttgttaaagaaattgataat
gagaagagaatgagacttctacagtttgttactggaacctgccgattgccagttggagga
tttgctgacctcatggggagcaatggaccacagaaattctgtattgaaaaagttgggaaa
gaaaattggttacccagaagtcatacctgttttaaccgcctggacctgccaccctacaag
agctatgagcaactgaaggaaaaactgttatttgccattgaagaaacagaaggatttgga
caagagtga
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