KEGG   Pteropus vampyrus (Indian flying fox): 120604974
Entry
120604974         CDS       T07511                                 
Symbol
CDK4
Name
(RefSeq) cyclin-dependent kinase 4 isoform X1
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
pgig  Pteropus vampyrus (Indian flying fox)
Pathway
pgig01522  Endocrine resistance
pgig04110  Cell cycle
pgig04115  p53 signaling pathway
pgig04151  PI3K-Akt signaling pathway
pgig04218  Cellular senescence
pgig04530  Tight junction
pgig04660  T cell receptor signaling pathway
pgig04933  AGE-RAGE signaling pathway in diabetic complications
pgig04934  Cushing syndrome
pgig05160  Hepatitis C
pgig05162  Measles
pgig05163  Human cytomegalovirus infection
pgig05164  Influenza A
pgig05165  Human papillomavirus infection
pgig05166  Human T-cell leukemia virus 1 infection
pgig05167  Kaposi sarcoma-associated herpesvirus infection
pgig05169  Epstein-Barr virus infection
pgig05200  Pathways in cancer
pgig05203  Viral carcinogenesis
pgig05212  Pancreatic cancer
pgig05214  Glioma
pgig05218  Melanoma
pgig05219  Bladder cancer
pgig05220  Chronic myeloid leukemia
pgig05222  Small cell lung cancer
pgig05223  Non-small cell lung cancer
pgig05224  Breast cancer
pgig05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:pgig00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    120604974 (CDK4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    120604974 (CDK4)
   04115 p53 signaling pathway
    120604974 (CDK4)
   04218 Cellular senescence
    120604974 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    120604974 (CDK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    120604974 (CDK4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    120604974 (CDK4)
   05203 Viral carcinogenesis
    120604974 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    120604974 (CDK4)
   05225 Hepatocellular carcinoma
    120604974 (CDK4)
   05214 Glioma
    120604974 (CDK4)
   05220 Chronic myeloid leukemia
    120604974 (CDK4)
   05218 Melanoma
    120604974 (CDK4)
   05219 Bladder cancer
    120604974 (CDK4)
   05224 Breast cancer
    120604974 (CDK4)
   05222 Small cell lung cancer
    120604974 (CDK4)
   05223 Non-small cell lung cancer
    120604974 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    120604974 (CDK4)
   05160 Hepatitis C
    120604974 (CDK4)
   05164 Influenza A
    120604974 (CDK4)
   05162 Measles
    120604974 (CDK4)
   05163 Human cytomegalovirus infection
    120604974 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    120604974 (CDK4)
   05169 Epstein-Barr virus infection
    120604974 (CDK4)
   05165 Human papillomavirus infection
    120604974 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    120604974 (CDK4)
   04934 Cushing syndrome
    120604974 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    120604974 (CDK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pgig01001]
    120604974 (CDK4)
Enzymes [BR:pgig01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     120604974 (CDK4)
Protein kinases [BR:pgig01001]
 Serine/threonine kinases: CMGC group
  CDK family
   120604974 (CDK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kdo ABC1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 120604974
NCBI-ProteinID: XP_039721784
UniProt: A0A6P3RQE0
LinkDB
Position
Unknown
AA seq 302 aa
MATPRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGAGGGLPISTVREVALLR
RLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDLM
RQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYR
APEVLLQSTYATPVDLWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPRD
VSLPRGAFSPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLQKAEGN
PE
NT seq 909 nt   +upstreamnt  +downstreamnt
atggctacccctcgatatgagccagtggctgagattggtgttggtgcctatggaacggtg
tacaaggcccgtgatccccacagtggccactttgtcgccctcaagagcgtgagagttccc
aatggaggtgctggagggggccttcccatcagcacagttcgtgaggttgctttactgagg
cggctggaggcttttgagcatcccaatgttgtccggctgatggatgtctgtgccacagcc
cgaactgaccgggaaaccaaagtgaccctggtgtttgagcatgtggaccaagacctaagg
acgtatctggataaggcacccccaccaggcttgccagtggagaccatcaaggatctgatg
cgccagtttctaagaggcctagatttccttcatgccaactgcattgttcaccgggaccta
aagccagagaacattctggtgacaagtggtgggacagtcaagctggctgactttggcctg
gccagaatctacagctaccagatggcacttacacctgtggttgttacactctggtaccgt
gctccagaagttcttctgcagtctacgtatgcaacacctgtggacttgtggagtgttggc
tgtatcttcgctgagatgtttcgtcgaaagcctctcttctgcggaaattctgaagctgac
cagttaggcaaaatctttgacttgattgggctgcccccagaggatgactggccccgagat
gtctctctaccccggggagccttttcccccagagggccccgtccagtgcagtcggtggta
cctgagatggaggagtctggagcacagctgctgctggagatgctgacttttaacccacac
aagcgaatctctgccttccgagccctgcagcattcttatctacaaaaggcagaaggtaac
ccagagtga

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