Pteropus vampyrus (Indian flying fox): 120605338
Help
Entry
120605338 CDS
T07511
Symbol
IRS2
Name
(RefSeq) insulin receptor substrate 2 isoform X1
KO
K07187
insulin receptor substrate 2
Organism
pgig
Pteropus vampyrus (Indian flying fox)
Pathway
pgig04022
cGMP-PKG signaling pathway
pgig04068
FoxO signaling pathway
pgig04081
Hormone signaling
pgig04140
Autophagy - animal
pgig04152
AMPK signaling pathway
pgig04211
Longevity regulating pathway
pgig04213
Longevity regulating pathway - multiple species
pgig04910
Insulin signaling pathway
pgig04920
Adipocytokine signaling pathway
pgig04923
Regulation of lipolysis in adipocytes
pgig04930
Type II diabetes mellitus
pgig04931
Insulin resistance
pgig04932
Non-alcoholic fatty liver disease
pgig04935
Growth hormone synthesis, secretion and action
pgig05010
Alzheimer disease
pgig05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
pgig00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
120605338 (IRS2)
04022 cGMP-PKG signaling pathway
120605338 (IRS2)
04152 AMPK signaling pathway
120605338 (IRS2)
09133 Signaling molecules and interaction
04081 Hormone signaling
120605338 (IRS2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
120605338 (IRS2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
120605338 (IRS2)
04923 Regulation of lipolysis in adipocytes
120605338 (IRS2)
04920 Adipocytokine signaling pathway
120605338 (IRS2)
04935 Growth hormone synthesis, secretion and action
120605338 (IRS2)
09149 Aging
04211 Longevity regulating pathway
120605338 (IRS2)
04213 Longevity regulating pathway - multiple species
120605338 (IRS2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
120605338 (IRS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
120605338 (IRS2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
120605338 (IRS2)
04932 Non-alcoholic fatty liver disease
120605338 (IRS2)
04931 Insulin resistance
120605338 (IRS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
IRS
PH
PH_11
MEKK4_N
Mcp5_PH
Motif
Other DBs
NCBI-GeneID:
120605338
NCBI-ProteinID:
XP_039722218
LinkDB
All DBs
Position
Unknown
AA seq
1407 aa
AA seq
DB search
MASPPLQGPPGLAGGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGAVGDEA
TATAGGGPAPQPPRLEYYESEKKWRSKAGAPKRVISLDCCLNINKRADAKHKYLIALYTK
DEYFAVAAENEQEQEGWYRALTDLVSEGRAVAGDAPSSAATAGSCSASLPGALGGSAGAD
DSYGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQ
LMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFR
PRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCRV
RTASEGDGGAATGTGAAGGRPVSVAGSPLSPGPVRAPLSRSHTLSGGCGSRASKVTLTPA
GGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPHLQHPLQHHAGQRP
SSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGSGSELYGY
MTMDRPLSHCGRPYRRVSGDGAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMR
ATFSGSSGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGTDDGYMPMTPGVAL
MGGGSGSCKSDDYMPMSPTSVSAPKQILQPRAAAAALPPTGAAVPAPASVASRAFPVNGA
SYKANSPAESSPEDSGYMRMWCGSKLTMENTDSKLLPNGDYLNMSPSDAGTSETPPDDFS
AALHSGGEMLRGIPGYCYSSLPRSYKAPYTCSGDNDQYVLMSSPVGRILEEERPEPQASA
GTTQSASVFVAGMGGGSHTQLPHSVVPSPGRLSGSGCGHPEGFLNQRCRAVRPTRLSLEG
LQTLPRMHEYPLPPEPKSPGEYINIDFSETGARLSPPAPPLLASAASSSSLLSASSPASS
LGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPSTQSGDPVGSLDALLSPEASSQYPPL
PPRPAAPSSSLQPQPPPPPPPGELYRLPPASTSQGPSAASSSSSETGDNGDYTEMAFGVA
ATPPQPIVAPPKPEGARVTSPTSGLKRLSLMDQVSGVEAFLQAGQPPDPHRGAKVIRADP
QGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKNSEGGGSGILGGGDEP
SSSPHQLQPPLPQQARPWTPNQPGGLVGCPGSSGSPMRRETSAGFQNGLNYIAIDVRDEP
GLLSPQQQHPHSQQHPHSQSGDKSTWGRTRSLGGLISAVGANSTGGVCGGPGPGALPSAN
TYASIDFLSHHLKEATIVKDTHDLPRKAPLSCAEEASWPSAAPSTHNASCSENLPLLDPL
PSATVAAVVGGGQSHLAGQLCVSNPSG
NT seq
4224 nt
NT seq
+upstream
nt +downstream
nt
atggcgagcccgccgctgcaggggccccccgggttggcgggcggcgacggccccaacctc
aacaacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcag
aagcacggccacaagcgcttcttcgtgctgcgcggccccggcgcggttggcgacgaggca
actgccacagcgggcgggggtccggcgccgcagccgccgcggctcgagtactacgagagc
gagaagaagtggcggagcaaggctggcgccccgaagcgggtcatctcgcttgactgctgc
ttgaacatcaacaagcgcgccgacgccaagcacaagtacctgatcgccctctacaccaag
gacgagtacttcgccgtggcggccgagaacgagcaggagcaggagggctggtaccgcgca
ctcaccgacctggtcagcgagggccgcgcggttgccggcgacgcgccctcctccgccgcc
actgctgggtcctgcagcgcctctttgcctggcgccctgggcggctcggccggcgctgat
gacagctacgggctggtggcgcccgccacagccgcctaccgcgaggtgtggcaggtgaac
ctgaagcccaagggcctgggtcagagcaaaaacctgacgggcgtgtaccgcctttgcctg
tcggcgcgcaccatcggcttcgtgaagctcaactgcgaacagccgtcggtgactctgcaa
ctcatgaacattcgccgctgcggccactcggacagtttcttcttcatcgaggttggccgc
tcagctgtcaccggccccggcgagctgtggatgcaggccgacgactcggtggtggcgcag
aacatccatgagaccatcctagaggccatgaaggcgctcaaggagctctttgagttccgg
ccgcgcagcaagagccagtcgtcgggatcatcagccacgcaccccattagcgtccccggc
gcgcgccgtcaccaccacctggtcaacctgccccccagccagacgggcttggtgcggcgc
tcgcgcaccgacagcctggctgccaccccgccagccgccaaatgtagctcctgccgggtg
cgcacggccagcgagggcgacggcggcgcagcgacggggactggagcggcgggcggcagg
cccgtgtcggtggcggggagccccctgagcccggggcccgtgcgcgcgccgcttagtcgt
tcgcataccctgagcggcggctgcggcagccgcgcgagcaaggtaacgctgacgccggca
gggggcgccctgcagcacagccgctcgatgtccatgcccgtggctcactcgccccctgcc
gctaccagccccggaagcctgtcttccagcagtgggcacggctcgggctcctacccgccg
cctccgggcccgcacccacacctacagcaccccttgcagcaccacgcgggccagcggcct
tccagcggcagcgcctcagcctccggctcccccagcgatcccggctttatgtctctggat
gagtacggctccagccctggggacctgagagccttctgtagccacaggagcaacactcct
gagtccatcgccgagacacctccggccagggacggcagcgggagtgagctgtacggctac
atgaccatggacaggcccctgagccactgtggccgcccctaccgtcgtgtctcaggggac
ggagctcaggacttggacagagggctaaggaagaggacttactccctgaccacacctgcc
cggcagcgaccggtgccccagccctcctcagcgtccctggatgaatacaccctgatgcgg
gccaccttctctggcagctcgggccgcctctgcccgtcctgccctgcgtcttctcccaaa
gtggcctaccacccctatcctgaggactacggcgacattgagattgggtcccataggagc
tccagcagtaacctgggcacggacgatggttacatgcccatgacccctggcgtggccctc
atgggtggtggcagtggcagctgcaagagtgatgactacatgcccatgagtcccaccagc
gtgtctgccccaaagcagatcttgcagccacgggctgctgcagcagccttgccccccaca
ggagctgcagtgccagcgccggcctctgtggccagcagggcctttccagtgaacggggcc
agctacaaggccaactccccggccgagagctcacccgaagacagtggatacatgcgcatg
tggtgtggttccaagctgaccatggagaatacagacagcaagctgcttcccaacggggac
tacctcaacatgtcccccagcgatgcaggcacctcggaaaccccaccagatgacttctca
gcagccttgcatagcggtggggagatgctcaggggcattcctggctactgctacagctct
ttgccccgctcctataaggctccttacacctgtagtggggacaatgaccagtacgtactc
atgagctccccggtggggcgcatcctagaagaggagaggccagagccacaggccagcgca
gggaccacgcagtcggccagcgtcttcgtggctgggatgggtgggggcagccacacccag
cttcctcactccgtagtgccttcgcctgggaggctgagtggcagcggctgtggccaccca
gagggtttcctgaaccaacgctgtcgggcagtgcgacccacgcgcctgtccctggagggg
cttcagaccctacccaggatgcacgagtatcctctgccgccggaacccaagagcccgggc
gaatacatcaacattgactttagcgaaaccggagcgcgcttgtcaccgcctgcccctccg
ctgctggcttccgctgcctcgtcctcctcgctgctgtctgccagcagcccagcctcatcc
ctgggctctggtactccgggcacaagcagcgacagccggcagcgctccccgctctccgac
tacatgaacctcgatttcagttcgcccaagtcacccaaaccgagtacccagagcggggac
ccggtggggtccttggatgccctcctgtctcctgaggcctcctcccagtacccgccactg
cctcctcgccctgctgccccctcctcctccttgcagccgcagccgcctcccccacctccc
ccaggggagctgtaccgcctgcctccagcatccacatcccagggccccagcgctgcctcc
tcttcgtcctcggagactggggacaatggtgactacaccgagatggcctttggcgtagct
gccaccccgccacaacccatcgtggcccccccgaagccggaaggtgcccgtgtgaccagc
cccacgtccggcctgaagaggctgagtctcatggatcaggtgtctggagtggaggccttt
ttgcaggctggccagcccccagacccacaccggggggccaaggtcatccgggcagacccg
caggggggccgccgccgccacagttccgagaccttttcctcgaccaccactgtgaccccc
gtgtccccatccttcgcccacaacccgaagcgccacaactcggcctccgtggaaaacgtc
tctctcaggaaaaacagcgaaggaggtggcagtggcatccttggtgggggcgacgaacct
tcctcttccccccaccagttgcaaccacccctcccccagcaggcacggccatggacaccg
aatcagcctgggggtctggttggctgccctgggagcagtggctctcctatgcgcagggag
acctctgccggcttccagaatggcctcaactacatcgccatcgatgtgagagatgagcca
gggctgttgtctccccagcaacaacacccgcattcgcagcaacatccacattcgcagtca
ggcgacaagagcacttggggccggacccgtagcctcgggggtctcatcagcgctgtgggg
gccaacagcaccggtggagtgtgtggggggcccggccctggcgccctaccctcagccaac
acctatgccagcattgacttcttgtcccatcacctgaaggaggccaccattgtgaaagac
acccatgatctacccagaaaagcccccctctcctgtgcagaggaggcctcctggccatca
gcagccccctccacccataatgcctcctgctctgagaacctgcctctgctggaccccctg
ccctccgccacagtggctgctgttgtcgggggagggcagtcccacttggctgggcagctc
tgtgtttccaacccatcaggctga
DBGET
integrated database retrieval system
