Pteropus giganteus (Indian flying fox): 120608487
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Entry
120608487 CDS
T07511
Symbol
HSD11B1
Name
(RefSeq) corticosteroid 11-beta-dehydrogenase isozyme 1 isoform X1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
pgig
Pteropus giganteus (Indian flying fox)
Pathway
pgig00140
Steroid hormone biosynthesis
pgig00980
Metabolism of xenobiotics by cytochrome P450
pgig01100
Metabolic pathways
pgig05204
Chemical carcinogenesis - DNA adducts
Module
pgig_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
pgig00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
120608487 (HSD11B1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
120608487 (HSD11B1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
120608487 (HSD11B1)
Enzymes [BR:
pgig01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
120608487 (HSD11B1)
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Paralog
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
THF_DHG_CYH_C
Shikimate_DH
2-Hacid_dh_C
Pyr_redox_2
Pyr_redox_3
AdoHcyase_NAD
Motif
Other DBs
NCBI-GeneID:
120608487
NCBI-ProteinID:
XP_039726244
LinkDB
All DBs
Position
Unknown
AA seq
296 aa
AA seq
DB search
MGFVKNYLFPILGIFLAYYYYSASEEFRPEMLQGKKVIVTGASKGIGKEMAYHLAKMGAH
VMVTARSEETLKKVVSHCLELGAASAHYLAGTMENMTFAEQFVAKTGQLMGGLDMLILNH
ITYVPLQLFRDDVRLVRDSMEVNFLSYVVLSVAALPMLKQSNGSIVVVSSVAGKISNPLI
APYAASKFALDGFFSSIRKEYSMAKVNVSITLCILGLINTDTAMKAVSGILNSDASPKEE
CALEIIKGGALRQEEVYYDRSVWTSLLLKNPGRKILEFFSHRSYNMDRFIKNEELP
NT seq
891 nt
NT seq
+upstream
nt +downstream
nt
atgggttttgtgaaaaactatctgttccctattctggggatcttcttggcctactactac
tattctgcaagtgaggaattcagaccagagatgctccaaggaaagaaagtgattgtcaca
ggggccagcaaggggatcggaaaagagatggcctatcatctggcgaagatgggagcccat
gtgatggtgacagcaaggtcagaagaaactctaaagaaggtggtatctcactgcctagaa
cttggagcagcctcggcacactaccttgctggcaccatggagaacatgacctttgcggaa
caatttgttgccaaaactggacagctcatgggaggactagacatgctcattctcaaccac
atcacctacgttcctctgcaactctttcgtgatgacgtccgtctcgtgcgtgacagcatg
gaggtcaacttcctcagctacgtggtcttgagtgtggctgccctgcccatgctgaagcag
agcaacggcagcatcgtcgtcgtctcctcggtggctgggaaaatatctaatccacttatt
gctccctatgctgcaagcaagtttgctctggatgggtttttctcctccatcaggaaggaa
tattcaatggccaaggtcaatgtgtcaatcactctctgtatcctcggcctcataaacacg
gacaccgccatgaaggcagtttctggaatactcaacagtgatgcatctccaaaggaagaa
tgtgccttggagattatcaaagggggagctctgcgccaagaggaagtgtattatgacaga
tcggtatggacctctctcctgctgaaaaatccagggaggaagatcctggaatttttctcc
cacagaagttataatatggacagatttataaaaaatgaggaacttccttag
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