KEGG   Phyllostomus hastatus (greater spear-nosed bat): 123810433
Entry
123810433         CDS       T07912                                 
Symbol
TNF
Name
(RefSeq) tumor necrosis factor isoform X1
  KO
K03156  tumor necrosis factor superfamily, member 2
Organism
phas  Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas01523  Antifolate resistance
phas04010  MAPK signaling pathway
phas04060  Cytokine-cytokine receptor interaction
phas04061  Viral protein interaction with cytokine and cytokine receptor
phas04064  NF-kappa B signaling pathway
phas04071  Sphingolipid signaling pathway
phas04150  mTOR signaling pathway
phas04210  Apoptosis
phas04217  Necroptosis
phas04350  TGF-beta signaling pathway
phas04380  Osteoclast differentiation
phas04612  Antigen processing and presentation
phas04620  Toll-like receptor signaling pathway
phas04621  NOD-like receptor signaling pathway
phas04622  RIG-I-like receptor signaling pathway
phas04625  C-type lectin receptor signaling pathway
phas04640  Hematopoietic cell lineage
phas04650  Natural killer cell mediated cytotoxicity
phas04657  IL-17 signaling pathway
phas04660  T cell receptor signaling pathway
phas04664  Fc epsilon RI signaling pathway
phas04668  TNF signaling pathway
phas04920  Adipocytokine signaling pathway
phas04930  Type II diabetes mellitus
phas04931  Insulin resistance
phas04932  Non-alcoholic fatty liver disease
phas04933  AGE-RAGE signaling pathway in diabetic complications
phas04936  Alcoholic liver disease
phas04940  Type I diabetes mellitus
phas05010  Alzheimer disease
phas05014  Amyotrophic lateral sclerosis
phas05020  Prion disease
phas05022  Pathways of neurodegeneration - multiple diseases
phas05132  Salmonella infection
phas05133  Pertussis
phas05134  Legionellosis
phas05135  Yersinia infection
phas05140  Leishmaniasis
phas05142  Chagas disease
phas05143  African trypanosomiasis
phas05144  Malaria
phas05145  Toxoplasmosis
phas05146  Amoebiasis
phas05152  Tuberculosis
phas05160  Hepatitis C
phas05161  Hepatitis B
phas05163  Human cytomegalovirus infection
phas05164  Influenza A
phas05165  Human papillomavirus infection
phas05166  Human T-cell leukemia virus 1 infection
phas05168  Herpes simplex virus 1 infection
phas05169  Epstein-Barr virus infection
phas05170  Human immunodeficiency virus 1 infection
phas05171  Coronavirus disease - COVID-19
phas05205  Proteoglycans in cancer
phas05310  Asthma
phas05321  Inflammatory bowel disease
phas05322  Systemic lupus erythematosus
phas05323  Rheumatoid arthritis
phas05330  Allograft rejection
phas05332  Graft-versus-host disease
phas05410  Hypertrophic cardiomyopathy
phas05414  Dilated cardiomyopathy
phas05417  Lipid and atherosclerosis
phas05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:phas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123810433 (TNF)
   04350 TGF-beta signaling pathway
    123810433 (TNF)
   04064 NF-kappa B signaling pathway
    123810433 (TNF)
   04668 TNF signaling pathway
    123810433 (TNF)
   04071 Sphingolipid signaling pathway
    123810433 (TNF)
   04150 mTOR signaling pathway
    123810433 (TNF)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    123810433 (TNF)
   04061 Viral protein interaction with cytokine and cytokine receptor
    123810433 (TNF)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    123810433 (TNF)
   04217 Necroptosis
    123810433 (TNF)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    123810433 (TNF)
   04620 Toll-like receptor signaling pathway
    123810433 (TNF)
   04621 NOD-like receptor signaling pathway
    123810433 (TNF)
   04622 RIG-I-like receptor signaling pathway
    123810433 (TNF)
   04625 C-type lectin receptor signaling pathway
    123810433 (TNF)
   04650 Natural killer cell mediated cytotoxicity
    123810433 (TNF)
   04612 Antigen processing and presentation
    123810433 (TNF)
   04660 T cell receptor signaling pathway
    123810433 (TNF)
   04657 IL-17 signaling pathway
    123810433 (TNF)
   04664 Fc epsilon RI signaling pathway
    123810433 (TNF)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    123810433 (TNF)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    123810433 (TNF)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    123810433 (TNF)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    123810433 (TNF)
   05170 Human immunodeficiency virus 1 infection
    123810433 (TNF)
   05161 Hepatitis B
    123810433 (TNF)
   05160 Hepatitis C
    123810433 (TNF)
   05171 Coronavirus disease - COVID-19
    123810433 (TNF)
   05164 Influenza A
    123810433 (TNF)
   05168 Herpes simplex virus 1 infection
    123810433 (TNF)
   05163 Human cytomegalovirus infection
    123810433 (TNF)
   05169 Epstein-Barr virus infection
    123810433 (TNF)
   05165 Human papillomavirus infection
    123810433 (TNF)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    123810433 (TNF)
   05135 Yersinia infection
    123810433 (TNF)
   05133 Pertussis
    123810433 (TNF)
   05134 Legionellosis
    123810433 (TNF)
   05152 Tuberculosis
    123810433 (TNF)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    123810433 (TNF)
   05144 Malaria
    123810433 (TNF)
   05145 Toxoplasmosis
    123810433 (TNF)
   05140 Leishmaniasis
    123810433 (TNF)
   05142 Chagas disease
    123810433 (TNF)
   05143 African trypanosomiasis
    123810433 (TNF)
  09163 Immune disease
   05310 Asthma
    123810433 (TNF)
   05322 Systemic lupus erythematosus
    123810433 (TNF)
   05323 Rheumatoid arthritis
    123810433 (TNF)
   05321 Inflammatory bowel disease
    123810433 (TNF)
   05330 Allograft rejection
    123810433 (TNF)
   05332 Graft-versus-host disease
    123810433 (TNF)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    123810433 (TNF)
   05014 Amyotrophic lateral sclerosis
    123810433 (TNF)
   05020 Prion disease
    123810433 (TNF)
   05022 Pathways of neurodegeneration - multiple diseases
    123810433 (TNF)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123810433 (TNF)
   05418 Fluid shear stress and atherosclerosis
    123810433 (TNF)
   05410 Hypertrophic cardiomyopathy
    123810433 (TNF)
   05414 Dilated cardiomyopathy
    123810433 (TNF)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    123810433 (TNF)
   04940 Type I diabetes mellitus
    123810433 (TNF)
   04936 Alcoholic liver disease
    123810433 (TNF)
   04932 Non-alcoholic fatty liver disease
    123810433 (TNF)
   04931 Insulin resistance
    123810433 (TNF)
   04933 AGE-RAGE signaling pathway in diabetic complications
    123810433 (TNF)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    123810433 (TNF)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:phas04052]
    123810433 (TNF)
   00536 Glycosaminoglycan binding proteins [BR:phas00536]
    123810433 (TNF)
Cytokines and neuropeptides [BR:phas04052]
 Cytokines
  Tumor necrosis fators
   123810433 (TNF)
Glycosaminoglycan binding proteins [BR:phas00536]
 Heparan sulfate / Heparin
  Cytokines
   123810433 (TNF)
SSDB
Motif
Pfam: TNF
Other DBs
NCBI-GeneID: 123810433
NCBI-ProteinID: XP_045682136
LinkDB
Position
Unknown
AA seq 230 aa
MSTESMIRDVELAEKVLPKKAGGHQGSRRCLCLSLFSFFLVAGATTLFCLLHFGVIGPQR
EEQFLIGPSLARTLGLSSRTPSDKPVAHVVANQQTVGQLQWKNQVANALLANGVQLKNNQ
LVVPLDGLYLIYSQVLFKGQGCPPTHLLLTHTISRYSASYAQKVNLLSAIKSPCQRETPE
GTDAKPWYEPIYLGGVFQLEKDDQLSAEVNLPDYLDFAEFGQVYFGLIAL
NT seq 693 nt   +upstreamnt  +downstreamnt
atgagcactgaaagcatgatccgggacgtggagctggctgagaaggtgctccccaagaag
gcagggggtcaccagggctccagacggtgcttgtgcctcagcctcttctccttcttcctc
gtggcaggagccactacactcttctgtctgttgcacttcggtgtgatcggcccccagagg
gaagagcagttcctaattggcccctcactggcccggacccttggattatcttctcgaacc
ccaagtgacaagcctgttgcccatgttgtagcaaatcagcaaactgtggggcagctgcag
tggaagaatcaggttgccaatgctctcctggccaatggtgtgcaactgaaaaacaaccag
ctggttgtgccgttggatgggctgtacctcatctactcccaggtcctcttcaagggccaa
ggctgccctcccacccacttgctcctcacccacaccatcagccgctattccgcctcctac
gcccaaaaggtcaacctcctctccgccatcaagagcccttgccaaagggagaccccagaa
gggactgacgccaagccctggtatgaacccatctacctgggaggggtcttccagctggag
aaagatgatcaactcagcgccgaggtcaacctgcctgactatctcgattttgccgaattt
gggcaggtctactttgggctcattgccctgtga

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