KEGG   Phyllostomus hastatus (greater spear-nosed bat): 123812897
Entry
123812897         CDS       T07912                                 
Symbol
CDK4
Name
(RefSeq) cyclin-dependent kinase 4
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
phas  Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas01522  Endocrine resistance
phas04110  Cell cycle
phas04115  p53 signaling pathway
phas04151  PI3K-Akt signaling pathway
phas04218  Cellular senescence
phas04530  Tight junction
phas04660  T cell receptor signaling pathway
phas04933  AGE-RAGE signaling pathway in diabetic complications
phas04934  Cushing syndrome
phas05160  Hepatitis C
phas05162  Measles
phas05163  Human cytomegalovirus infection
phas05164  Influenza A
phas05165  Human papillomavirus infection
phas05166  Human T-cell leukemia virus 1 infection
phas05167  Kaposi sarcoma-associated herpesvirus infection
phas05169  Epstein-Barr virus infection
phas05200  Pathways in cancer
phas05203  Viral carcinogenesis
phas05212  Pancreatic cancer
phas05214  Glioma
phas05218  Melanoma
phas05219  Bladder cancer
phas05220  Chronic myeloid leukemia
phas05222  Small cell lung cancer
phas05223  Non-small cell lung cancer
phas05224  Breast cancer
phas05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:phas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    123812897 (CDK4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    123812897 (CDK4)
   04115 p53 signaling pathway
    123812897 (CDK4)
   04218 Cellular senescence
    123812897 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    123812897 (CDK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    123812897 (CDK4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123812897 (CDK4)
   05203 Viral carcinogenesis
    123812897 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    123812897 (CDK4)
   05225 Hepatocellular carcinoma
    123812897 (CDK4)
   05214 Glioma
    123812897 (CDK4)
   05220 Chronic myeloid leukemia
    123812897 (CDK4)
   05218 Melanoma
    123812897 (CDK4)
   05219 Bladder cancer
    123812897 (CDK4)
   05224 Breast cancer
    123812897 (CDK4)
   05222 Small cell lung cancer
    123812897 (CDK4)
   05223 Non-small cell lung cancer
    123812897 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    123812897 (CDK4)
   05160 Hepatitis C
    123812897 (CDK4)
   05164 Influenza A
    123812897 (CDK4)
   05162 Measles
    123812897 (CDK4)
   05163 Human cytomegalovirus infection
    123812897 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    123812897 (CDK4)
   05169 Epstein-Barr virus infection
    123812897 (CDK4)
   05165 Human papillomavirus infection
    123812897 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    123812897 (CDK4)
   04934 Cushing syndrome
    123812897 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    123812897 (CDK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:phas01001]
    123812897 (CDK4)
Enzymes [BR:phas01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     123812897 (CDK4)
Protein kinases [BR:phas01001]
 Serine/threonine kinases: CMGC group
  CDK family
   123812897 (CDK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kdo Haspin_kinase ABC1 Kinase-like
Other DBs
NCBI-GeneID: 123812897
NCBI-ProteinID: XP_045685757
LinkDB
Position
Unknown
AA seq 303 aa
METLRYEPVAEIGVGAYGTVYKARDPNSGHFVALKSVRVPNGGGAGGGLPVSTVREVALL
RRLEAFEHPNVVRLVDVCASSRTDRETRVTLVFEHVDQDLRTYLNKVPPPGLPVETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSSGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSAYATPVDLWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFSPRGPRPVQSVIPEMEESGAQLLLEMLAFNPHKRISAFRALQHSYLQKAEG
SPE
NT seq 912 nt   +upstreamnt  +downstreamnt
atggaaactcttcgatatgagccagtggctgagattggtgttggtgcctatgggacggtg
tacaaggcccgtgatcccaacagtggccactttgtggccctcaagagcgtgcgagtccct
aatggaggaggtgctggaggaggccttcccgtgagcacagttcgtgaggtggccttactg
aggcggctggaagcttttgagcatcccaacgttgtccggctggtggatgtctgtgccagc
tcccgcaccgaccgggagaccagagtgaccctggtgtttgagcatgtggaccaagacctg
aggacatatctgaacaaggtacccccaccaggcttgccagtggagaccattaaggatctg
atgcgtcagtttctaagaggcctggatttccttcatgccaactgcattgttcaccgggac
ctgaagccagagaacattctggtgacaagtagtgggacagtcaagctggccgactttggc
ctggccagaatctacagctaccagatggcactcacacctgtggtcgtcacactctggtac
cgcgctccagaagttctgctgcagtctgcatacgccacacctgtggacttgtggagtgtt
ggctgtatcttcgcagagatgtttcgccgaaagcctctcttttgcggaaactctgaagct
gaccagttaggcaaaatctttgatctgattgggctgcccccagaggatgactggccccga
gacgtttctctgccccgaggagccttttcccccagagggccccgcccagtgcagtccgtg
atacctgagatggaggagtctggagcacagctgctgctggagatgctggcttttaaccca
cataagcgaatctctgccttccgagccctgcagcactcttatctacaaaaggcagaaggt
agcccagaatga

DBGET integrated database retrieval system