KEGG   Phyllostomus hastatus (greater spear-nosed bat): 123815667
Entry
123815667         CDS       T07912                                 
Symbol
FGFR3
Name
(RefSeq) fibroblast growth factor receptor 3 isoform X1
  KO
K05094  fibroblast growth factor receptor 3 [EC:2.7.10.1]
Organism
phas  Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas01521  EGFR tyrosine kinase inhibitor resistance
phas04010  MAPK signaling pathway
phas04014  Ras signaling pathway
phas04015  Rap1 signaling pathway
phas04020  Calcium signaling pathway
phas04144  Endocytosis
phas04151  PI3K-Akt signaling pathway
phas04550  Signaling pathways regulating pluripotency of stem cells
phas04810  Regulation of actin cytoskeleton
phas05200  Pathways in cancer
phas05206  MicroRNAs in cancer
phas05219  Bladder cancer
phas05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:phas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123815667 (FGFR3)
   04014 Ras signaling pathway
    123815667 (FGFR3)
   04015 Rap1 signaling pathway
    123815667 (FGFR3)
   04020 Calcium signaling pathway
    123815667 (FGFR3)
   04151 PI3K-Akt signaling pathway
    123815667 (FGFR3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    123815667 (FGFR3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    123815667 (FGFR3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    123815667 (FGFR3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123815667 (FGFR3)
   05206 MicroRNAs in cancer
    123815667 (FGFR3)
   05230 Central carbon metabolism in cancer
    123815667 (FGFR3)
  09162 Cancer: specific types
   05219 Bladder cancer
    123815667 (FGFR3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    123815667 (FGFR3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:phas01001]
    123815667 (FGFR3)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:phas04090]
    123815667 (FGFR3)
Enzymes [BR:phas01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     123815667 (FGFR3)
Protein kinases [BR:phas01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   123815667 (FGFR3)
CD molecules [BR:phas04090]
 Proteins
  123815667 (FGFR3)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase I-set Ig_3 ig Ig_2 V-set FGFR3_TM C2-set_2 ABC1 Pkinase_fungal
Other DBs
NCBI-GeneID: 123815667
NCBI-ProteinID: XP_045690054
LinkDB
Position
Unknown
AA seq 806 aa
MGAPVWAVALCVAVVVVTGTTSGLPAAEQRVVRRVAEDPEPEPGPQEQLVFGSGDTVELS
CHPPAGGPAGPTFWVKDGAGLAPSDRVLVGQQRLQVLNASHEDAGAYSCRQRLTQRVLCR
FSVRVTDAPSSGDDEDEEEEVEDTAGAPYWTRPERMEKKLLAVPAANTVRFRCPAAGNPT
PSITWLKNGKEFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVRNRLGSIRQTYTL
DVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGT
PYVTVLKSWISEAVEADARLRLANVSERDGGRYLCRASNFIGVSEKAFWLRVRGPPAAEE
ELVAAGEAGSVYAGVLSYGMGFVLFILVVAAVTLCRLRSPPKKGLAPAVHKVSRFPLKRQ
VTVSLESNSSMNSNTPLVRIARLSSGEGPALANVSELELPADPKWELPRARLTLGKPLGE
GCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIIN
LLGACTQGGPLYVLVEFAAKGNLREYLRARRPPGTDYSFDTCQLPEEQLTFKDLVSCAYQ
VARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKW
MAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCT
HDLYMIMRECWHAVPSQRPTFKQLVEDLDRILTVTSTDEYLDLSVPFEQYSPGGQDTPSS
SSSGDDSVFAHDLLHPAPPSSGGPQT
NT seq 2421 nt   +upstreamnt  +downstreamnt
atgggcgccccggtttgggctgtcgcgctctgcgtggctgtggtggtcgtgaccggtacc
acctcggggctcccggccgcagagcagcgcgtcgtgcggagagtggcagaggacccggag
cccgagcccggcccgcaggagcagctggtcttcggcagcggggacaccgtggagctgagc
tgccacccgcccgcaggcggccccgcagggcccaccttctgggttaaggacggggcagga
ctggcgccctcggaccgcgtcctggtggggcagcagcggctgcaggtgctcaatgcctcc
cacgaggacgccggggcctacagctgccggcagaggctcacccagcgcgtcctgtgccgc
ttcagcgtgcgggtgacagatgccccgtcctccggagacgatgaagatgaggaggaggag
gtggaagacacagcaggggccccgtactggacgcggcccgagcggatggagaagaagctg
ctggccgtgccggccgccaacaccgtccgcttccgctgcccggccgccggcaaccccacg
ccgtccatcacctggctgaagaatggcaaggagttccggggcgagcaccgcatcgggggc
atcaagctgcgtcaccagcagtggagcctggtcatggagagcgtggtgccctcggaccgg
ggcaactacacctgcgtcgtgcggaaccggctgggcagcatccggcagacctacaccctg
gacgtgctggagcgctctccgcaccggcccatcctgcaggcggggctgccggccaaccag
acggcggtgctgggcagcgacgtggagttccactgcaaggtgtacagcgacgcccagccc
cacatccagtggctgaagcacgtggaggtgaacggcagcaaggtggggccggacggcacg
ccctacgtcaccgtgctcaagtcctggatcagtgaggctgtggaggccgacgcacggctg
cgcctggccaatgtgtcggagcgcgacgggggccggtacctctgtcgggcgtccaatttc
ataggcgtgtccgagaaggccttttggctgcgcgttcgcgggccccccgcagccgaggag
gagctggtggcggcgggcgaggcgggcagcgtgtacgcgggcgtcctcagctacggcatg
ggcttcgtgctcttcatcctggtggtggccgccgtgacgctctgccgcctgcgcagcccc
cccaagaagggcctggcacccgccgtgcacaaggtctcccgtttcccgctgaagcgacag
gtaacagtgtccttggagtccaactcctccatgaactccaacacgccgctggtgcgcatc
gcccgcctgtcctcgggggagggccccgcgctggccaacgtctcggagctcgagctgccc
gccgaccccaagtgggagctgccccgggcccggctgaccctgggcaagcccctcggggag
ggctgcttcggccaggtggtcatggcggaggccatcggcatcgacaaggaccgggccgcc
aagccggtcaccgtggccgtgaagatgctgaaagacgatgccaccgacaaggacctgtcc
gacctggtgtcggagatggagatgatgaagatgatcgggaagcacaagaacatcatcaac
ctgctgggcgcctgcacgcagggcgggcccctgtatgtgctggtggagttcgcggccaag
ggcaacctgcgcgagtacctgcgggcccggcggcccccgggcacggactactccttcgac
acctgccagctgcccgaggagcagctcaccttcaaggacctggtgtcctgtgcctaccag
gtggcgcggggcatggagtacctggcctcccagaagtgcatccacagggacctggcggcc
cgcaacgtgctggtgacggaggacaacgtgatgaagatcgcggacttcggcctggcccgc
gacgtgcacaacctcgactactacaagaagaccaccaacggccggctgcctgtgaagtgg
atggcgcctgaggctctgttcgaccgtgtctacacccaccagagcgacgtgtggtccttc
ggggtcctgctctgggagatcttcaccctggggggctcgccgtacccaggcatccctgtg
gaggagctcttcaagctgctgaaggaaggccaccgcatggacaagccggccaactgcacg
catgacctgtacatgatcatgcgggagtgctggcacgccgtgccctcgcagcggcccacc
ttcaagcagctggtggaggacctggaccgcatcctcacggtgacgtccacggacgagtac
ctggacctgtcggtgcccttcgagcagtactcgcccggcggccaggacacccccagctcc
agctcctcgggggacgactccgtgtttgcccacgacctgctgcacccggccccccccagc
agcgggggcccgcagacgtga

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