KEGG   Phyllostomus hastatus (greater spear-nosed bat): 123817350
Entry
123817350         CDS       T07912                                 
Symbol
GRB2
Name
(RefSeq) growth factor receptor-bound protein 2
  KO
K04364  growth factor receptor-bound protein 2
Organism
phas  Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas01521  EGFR tyrosine kinase inhibitor resistance
phas01522  Endocrine resistance
phas04010  MAPK signaling pathway
phas04012  ErbB signaling pathway
phas04014  Ras signaling pathway
phas04062  Chemokine signaling pathway
phas04068  FoxO signaling pathway
phas04072  Phospholipase D signaling pathway
phas04150  mTOR signaling pathway
phas04151  PI3K-Akt signaling pathway
phas04380  Osteoclast differentiation
phas04510  Focal adhesion
phas04540  Gap junction
phas04550  Signaling pathways regulating pluripotency of stem cells
phas04630  JAK-STAT signaling pathway
phas04650  Natural killer cell mediated cytotoxicity
phas04660  T cell receptor signaling pathway
phas04662  B cell receptor signaling pathway
phas04664  Fc epsilon RI signaling pathway
phas04714  Thermogenesis
phas04722  Neurotrophin signaling pathway
phas04910  Insulin signaling pathway
phas04912  GnRH signaling pathway
phas04915  Estrogen signaling pathway
phas04917  Prolactin signaling pathway
phas04926  Relaxin signaling pathway
phas04935  Growth hormone synthesis, secretion and action
phas05034  Alcoholism
phas05160  Hepatitis C
phas05161  Hepatitis B
phas05163  Human cytomegalovirus infection
phas05165  Human papillomavirus infection
phas05200  Pathways in cancer
phas05203  Viral carcinogenesis
phas05205  Proteoglycans in cancer
phas05206  MicroRNAs in cancer
phas05207  Chemical carcinogenesis - receptor activation
phas05208  Chemical carcinogenesis - reactive oxygen species
phas05210  Colorectal cancer
phas05211  Renal cell carcinoma
phas05213  Endometrial cancer
phas05214  Glioma
phas05215  Prostate cancer
phas05220  Chronic myeloid leukemia
phas05221  Acute myeloid leukemia
phas05223  Non-small cell lung cancer
phas05224  Breast cancer
phas05225  Hepatocellular carcinoma
phas05226  Gastric cancer
phas05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:phas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123817350 (GRB2)
   04012 ErbB signaling pathway
    123817350 (GRB2)
   04014 Ras signaling pathway
    123817350 (GRB2)
   04630 JAK-STAT signaling pathway
    123817350 (GRB2)
   04068 FoxO signaling pathway
    123817350 (GRB2)
   04072 Phospholipase D signaling pathway
    123817350 (GRB2)
   04151 PI3K-Akt signaling pathway
    123817350 (GRB2)
   04150 mTOR signaling pathway
    123817350 (GRB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    123817350 (GRB2)
   04540 Gap junction
    123817350 (GRB2)
   04550 Signaling pathways regulating pluripotency of stem cells
    123817350 (GRB2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    123817350 (GRB2)
   04660 T cell receptor signaling pathway
    123817350 (GRB2)
   04662 B cell receptor signaling pathway
    123817350 (GRB2)
   04664 Fc epsilon RI signaling pathway
    123817350 (GRB2)
   04062 Chemokine signaling pathway
    123817350 (GRB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    123817350 (GRB2)
   04912 GnRH signaling pathway
    123817350 (GRB2)
   04915 Estrogen signaling pathway
    123817350 (GRB2)
   04917 Prolactin signaling pathway
    123817350 (GRB2)
   04926 Relaxin signaling pathway
    123817350 (GRB2)
   04935 Growth hormone synthesis, secretion and action
    123817350 (GRB2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    123817350 (GRB2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    123817350 (GRB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    123817350 (GRB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123817350 (GRB2)
   05206 MicroRNAs in cancer
    123817350 (GRB2)
   05205 Proteoglycans in cancer
    123817350 (GRB2)
   05207 Chemical carcinogenesis - receptor activation
    123817350 (GRB2)
   05208 Chemical carcinogenesis - reactive oxygen species
    123817350 (GRB2)
   05203 Viral carcinogenesis
    123817350 (GRB2)
   05231 Choline metabolism in cancer
    123817350 (GRB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    123817350 (GRB2)
   05225 Hepatocellular carcinoma
    123817350 (GRB2)
   05226 Gastric cancer
    123817350 (GRB2)
   05214 Glioma
    123817350 (GRB2)
   05221 Acute myeloid leukemia
    123817350 (GRB2)
   05220 Chronic myeloid leukemia
    123817350 (GRB2)
   05211 Renal cell carcinoma
    123817350 (GRB2)
   05215 Prostate cancer
    123817350 (GRB2)
   05213 Endometrial cancer
    123817350 (GRB2)
   05224 Breast cancer
    123817350 (GRB2)
   05223 Non-small cell lung cancer
    123817350 (GRB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    123817350 (GRB2)
   05160 Hepatitis C
    123817350 (GRB2)
   05163 Human cytomegalovirus infection
    123817350 (GRB2)
   05165 Human papillomavirus infection
    123817350 (GRB2)
  09165 Substance dependence
   05034 Alcoholism
    123817350 (GRB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    123817350 (GRB2)
   01522 Endocrine resistance
    123817350 (GRB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:phas04131]
    123817350 (GRB2)
Membrane trafficking [BR:phas04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    123817350 (GRB2)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH3_3 DUF7145 SH2_2 DUF5093 hSH3 SH3_4 DUF7063
Other DBs
NCBI-GeneID: 123817350
NCBI-ProteinID: XP_045692953
LinkDB
Position
Unknown
AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq 654 nt   +upstreamnt  +downstreamnt
atggaagccatcgccaaatatgacttcaaagccactgcagacgacgagctgagcttcaaa
aggggggacatcctcaaggttttgaatgaagaatgtgatcagaactggtacaaggcagaa
ctcaatgggaaagatggcttcattcccaagaattacatagaaatgaaaccgcatccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgctcagcaaacagcggcatgac
ggggccttcctcatccgagagagtgagagtgctcccggggacttctccctgtccgtcaag
tttggaaacgacgtgcagcacttcaaggtgctccgagacggagccggaaagtacttcctc
tgggtggtgaagttcaattctttgaatgagctcgtagattaccacagatctacatccgtc
tccagaaaccagcagatatttctccgggacatagaacaggtgccacagcaaccgacgtac
gtccaggccctctttgactttgacccccaggaggatggagagctggggttccgtcgggga
gactttatccacgtcatggataactcagaccccaactggtggaaaggggcttgccacggg
cagaccggcatgttcccccgcaattacgtcacccccgtgaaccggaacgtctaa

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