KEGG   Phyllostomus hastatus (greater spear-nosed bat): 123824482
Entry
123824482         CDS       T07912                                 
Symbol
CASP8
Name
(RefSeq) caspase-8 isoform X1
  KO
K04398  caspase 8 [EC:3.4.22.61]
Organism
phas  Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas01524  Platinum drug resistance
phas04115  p53 signaling pathway
phas04210  Apoptosis
phas04215  Apoptosis - multiple species
phas04217  Necroptosis
phas04620  Toll-like receptor signaling pathway
phas04621  NOD-like receptor signaling pathway
phas04622  RIG-I-like receptor signaling pathway
phas04623  Cytosolic DNA-sensing pathway
phas04625  C-type lectin receptor signaling pathway
phas04657  IL-17 signaling pathway
phas04668  TNF signaling pathway
phas04932  Non-alcoholic fatty liver disease
phas04936  Alcoholic liver disease
phas05010  Alzheimer disease
phas05016  Huntington disease
phas05022  Pathways of neurodegeneration - multiple diseases
phas05132  Salmonella infection
phas05134  Legionellosis
phas05142  Chagas disease
phas05145  Toxoplasmosis
phas05152  Tuberculosis
phas05160  Hepatitis C
phas05161  Hepatitis B
phas05162  Measles
phas05163  Human cytomegalovirus infection
phas05164  Influenza A
phas05165  Human papillomavirus infection
phas05167  Kaposi sarcoma-associated herpesvirus infection
phas05168  Herpes simplex virus 1 infection
phas05169  Epstein-Barr virus infection
phas05170  Human immunodeficiency virus 1 infection
phas05200  Pathways in cancer
phas05203  Viral carcinogenesis
phas05416  Viral myocarditis
phas05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:phas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    123824482 (CASP8)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    123824482 (CASP8)
   04215 Apoptosis - multiple species
    123824482 (CASP8)
   04217 Necroptosis
    123824482 (CASP8)
   04115 p53 signaling pathway
    123824482 (CASP8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    123824482 (CASP8)
   04621 NOD-like receptor signaling pathway
    123824482 (CASP8)
   04622 RIG-I-like receptor signaling pathway
    123824482 (CASP8)
   04623 Cytosolic DNA-sensing pathway
    123824482 (CASP8)
   04625 C-type lectin receptor signaling pathway
    123824482 (CASP8)
   04657 IL-17 signaling pathway
    123824482 (CASP8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123824482 (CASP8)
   05203 Viral carcinogenesis
    123824482 (CASP8)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    123824482 (CASP8)
   05161 Hepatitis B
    123824482 (CASP8)
   05160 Hepatitis C
    123824482 (CASP8)
   05164 Influenza A
    123824482 (CASP8)
   05162 Measles
    123824482 (CASP8)
   05168 Herpes simplex virus 1 infection
    123824482 (CASP8)
   05163 Human cytomegalovirus infection
    123824482 (CASP8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    123824482 (CASP8)
   05169 Epstein-Barr virus infection
    123824482 (CASP8)
   05165 Human papillomavirus infection
    123824482 (CASP8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    123824482 (CASP8)
   05134 Legionellosis
    123824482 (CASP8)
   05152 Tuberculosis
    123824482 (CASP8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    123824482 (CASP8)
   05142 Chagas disease
    123824482 (CASP8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    123824482 (CASP8)
   05016 Huntington disease
    123824482 (CASP8)
   05022 Pathways of neurodegeneration - multiple diseases
    123824482 (CASP8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123824482 (CASP8)
   05416 Viral myocarditis
    123824482 (CASP8)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    123824482 (CASP8)
   04932 Non-alcoholic fatty liver disease
    123824482 (CASP8)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    123824482 (CASP8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:phas01002]
    123824482 (CASP8)
Enzymes [BR:phas01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.61  caspase-8
     123824482 (CASP8)
Peptidases and inhibitors [BR:phas01002]
 Cysteine peptidases
  Family C14: caspase family
   123824482 (CASP8)
SSDB
Motif
Pfam: Peptidase_C14 DED ARM_TT21_5th
Other DBs
NCBI-GeneID: 123824482
NCBI-ProteinID: XP_045703614
LinkDB
Position
Unknown
AA seq 520 aa
MRLHEHTLLSTQATTTFHQLRTSMDLNNCLYEIGENLNSDEVASLKFLSVDYIPQKKQEH
IKDALMLFQRLQEKRMVEENNLSFLKELLFRVGRLDLLKKYLNTSEEEMKKELQIPGKAQ
ISAYRVMLFQISEDVKTSELPSFKFLLNKEISKSKLDDNVNLLDIFMEMEKRVLLGERNL
DTLKRICHQVDKSLLKKINDYEELSRGATCFFPKVSSLPCVIPNVSSSFVEEEVSLRMLS
VSDNSREQDCESSKEDSESQQTLDKTYRMTSKPRGFCVIFNNYDFHLARKNVPRLHNIKD
RNGTHLDAEALCSTFSMLHFDIVQHNDFTAEKICETLEEYQNKDHNNKDCFICCILSHGD
KGIIYGADGQEAPIHELTSYFTSSKCPSLAGKPKIFFIQACQGDNYQKGIAVETDSEEKE
DHLEMDLTLQKRYIPDEADFLLGMATVNNCVSYRSPMEGTWYIQSLCQSLKERCPRGDDI
LTILTEVNFEVSNKDDKKNMGKQMPQPTFTLTKKLFFPLN
NT seq 1563 nt   +upstreamnt  +downstreamnt
atgagactccatgaacataccctgttgagcacacaggctacaactacattccaccaacta
aggacaagtatggatctcaacaattgtctatatgaaattggagagaatctgaacagtgat
gaggtggcttccctcaagttcctaagtgtggattacataccacaaaagaagcaggaacac
atcaaagatgccttaatgttatttcagcgactccaggaaaagagaatggtggaggaaaac
aacttgtccttcttgaaggagcttctatttcgagttggtaggttggatctcctgaaaaag
tacctgaacaccagcgaagaagagatgaagaaggagcttcagataccgggcaaggctcag
atctctgcatacagggttatgctattccagatttcagaagatgtaaaaacatcggaatta
ccatcttttaagtttcttttgaacaaggagatctccaaaagtaaactggatgacaacgtg
aacttgcttgatattttcatggagatggagaagagggtccttcttggggaaagaaatttg
gacaccctaaaacgaatctgtcaccaagtcgacaagagcctgctgaagaaaatcaatgat
tatgaagaattaagcagaggtgctacatgtttctttcctaaagtatcctctctgccatgt
gtcattccaaatgtgtcttcatcatttgtagaggaggaggtgtcacttaggatgctgtca
gtgtcggacaattcaagagaacaggactgcgaatcttccaaggaggacagtgagtcacaa
cagacattggacaaaacttaccgaatgacaagcaagccccgggggttctgtgtgatcttt
aacaattatgactttcacctggcaaggaagaacgtgcccaggcttcacaacataaaggac
aggaatggaacacacttggatgcagaggctttgtgttccacttttagtatgcttcacttt
gatatagtgcagcacaacgacttcacagcagagaaaatctgtgaaactctggaagagtac
caaaacaaggaccacaataacaaagactgcttcatctgctgcatcctttcccatggagac
aagggcatcatctatggtgctgatgggcaggaagcccccatccatgagctgacttcatac
ttcactagttcaaaatgcccttcccttgcaggcaaacccaaaatctttttcatccaggct
tgtcaaggggataactaccaaaaaggtatagctgtagagactgactcagaagaaaaggaa
gaccatttagaaatggacttaacacttcagaaaagatacatcccagatgaggctgacttt
ctgctgggaatggccactgtgaacaattgtgtttcctaccgaagccctatggaggggacc
tggtatatccagtcactttgccagagcctgaaagaaagatgtcccaggggtgatgatatt
ctcaccatcctcacagaggtgaactttgaagtgagcaataaagatgacaagaagaatatg
gggaagcagatgccacagccgactttcactctgacaaaaaaactcttcttccctcttaat
tga

DBGET integrated database retrieval system