Phyllostomus hastatus (greater spear-nosed bat): 123833261
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Entry
123833261 CDS
T07912
Symbol
PTK2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
phas
Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas01522
Endocrine resistance
phas04012
ErbB signaling pathway
phas04062
Chemokine signaling pathway
phas04148
Efferocytosis
phas04151
PI3K-Akt signaling pathway
phas04360
Axon guidance
phas04370
VEGF signaling pathway
phas04510
Focal adhesion
phas04670
Leukocyte transendothelial migration
phas04810
Regulation of actin cytoskeleton
phas04935
Growth hormone synthesis, secretion and action
phas05100
Bacterial invasion of epithelial cells
phas05135
Yersinia infection
phas05146
Amoebiasis
phas05163
Human cytomegalovirus infection
phas05165
Human papillomavirus infection
phas05170
Human immunodeficiency virus 1 infection
phas05200
Pathways in cancer
phas05202
Transcriptional misregulation in cancer
phas05205
Proteoglycans in cancer
phas05208
Chemical carcinogenesis - reactive oxygen species
phas05222
Small cell lung cancer
phas05417
Lipid and atherosclerosis
phas05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
phas00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
123833261 (PTK2)
04370 VEGF signaling pathway
123833261 (PTK2)
04151 PI3K-Akt signaling pathway
123833261 (PTK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
123833261 (PTK2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
123833261 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
123833261 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
123833261 (PTK2)
04062 Chemokine signaling pathway
123833261 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
123833261 (PTK2)
09158 Development and regeneration
04360 Axon guidance
123833261 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123833261 (PTK2)
05202 Transcriptional misregulation in cancer
123833261 (PTK2)
05205 Proteoglycans in cancer
123833261 (PTK2)
05208 Chemical carcinogenesis - reactive oxygen species
123833261 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
123833261 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
123833261 (PTK2)
05163 Human cytomegalovirus infection
123833261 (PTK2)
05165 Human papillomavirus infection
123833261 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
123833261 (PTK2)
05100 Bacterial invasion of epithelial cells
123833261 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
123833261 (PTK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
123833261 (PTK2)
05418 Fluid shear stress and atherosclerosis
123833261 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
123833261 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
phas01001
]
123833261 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
phas01009
]
123833261 (PTK2)
Enzymes [BR:
phas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
123833261 (PTK2)
Protein kinases [BR:
phas01001
]
Non-receptor tyrosine kinases
FAK family
123833261 (PTK2)
Protein phosphatases and associated proteins [BR:
phas01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
123833261 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_N_2
FERM_C_FAK1
FERM_M
Kinase-like
FERM_F2
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
123833261
NCBI-ProteinID:
XP_045717331
LinkDB
All DBs
Position
Unknown
AA seq
1105 aa
AA seq
DB search
MLLDRAGRGARRPAAVCMERSGCSPFPVCWAEEYDRYLASSRIMAAAYLDPNLNHTPNSS
TKTHLGTGAERSPGAMERVLKVFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHKV
KHVACYGFRLSHLRSEEVHWLHLDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQF
TEDKPTLNFFYQQVKSDYMSEIADQVDQDIALKLGCLEIRRSYWEMRGNALEKKSNYEVL
EKDVGLKRFFPRSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKEC
FKCALGSSWVISVELAIGPEEGISYLTDKGCSPTHLADFNQVQTIQYSNSEDKDRKGVLQ
LRVAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGASQSFIIRPQKEGERALPSIPKLA
NSEKQGVRTHAVSVSETDDYAEIVDEDEAYTMPSKSYGIDEARDYEIQRERIELGRCIGE
GQFGDVHQGVYVGPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVI
TENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAAR
NVLVSSSDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGV
CMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFT
ELKAQLSTVLEEEKLQHEERMRMESRRQVAVSWDSGGSDEAPPKPSRPGYPSPRSSEGFY
PSPQHAVQANHYQVSGYPGSHGVPPMAGSMYPGQAPLLDQTDSWNHRPPEMPVWQPGVED
SAARDLRGIGQALPAHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSVDREDGG
LQGPAGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPGDSYNEGVKPWRLQPQ
EISPPPTANLDRSNDRVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKDVGLALRTLLAT
VDETIPSLPASTHREIEMAQKLLNSDLGELIGKMKLAQQYVLTSLQQEYKKQMLTAAHAL
AVDAKNLLDVIDQARLKMLSQTRPH
NT seq
3318 nt
NT seq
+upstream
nt +downstream
nt
atgttgctggaccgggcgggccgcggggcccggagaccggcagccgtctgcatggagagg
agcggctgcagccccttcccggtgtgctgggccgaagaatatgacaggtacctagcatct
agcaggataatggcggctgcttacctggacccaaacttgaatcacacaccaaattccagt
accaagacgcacctggggaccggtgcggagcgctccccgggagccatggagcgagtgctg
aaagtctttcactattttgaaagcaacagtgagccgactacgtgggccagcatcatcagg
cacggagacgccaccgacgtcaggggcatcattcagaagatagtggacagtcacaaggta
aagcacgtggcctgctatggattccggctcagccacctgcggtcagaggaggtccactgg
ctgcacttggacatgggcgtctccagcgtgcgggagaagtatgagctcgcgcacccaccg
gaggagtggaaatacgaattgagaattcgttatttgccgaaaggatttctcaaccagttt
actgaagacaagccaactttgaacttcttctatcagcaggtgaagagcgattatatgtcc
gaaatagctgaccaagtggaccaggacattgctttgaagttgggttgtctggaaatacgg
cggtcatactgggagatgcggggcaacgctctggaaaagaagtcgaactatgaagtactg
gagaaagatgtcggcttgaagcggttcttccctaggagtttactggactccgtcaaggcc
aagacactaaggaaactgattcaacagacgtttagacagtttgccaaccttaacagagaa
gaaagcattctgaagttcttcgagatcctctccccagtgtacagatttgataaggagtgc
ttcaagtgcgctcttggttcaagctgggtgatttcggttgaactggcgatcggccccgag
gaaggcatcagctacctcaccgacaagggctgcagccccacgcatctggccgacttcaac
caagtgcagaccatccagtactcgaacagcgaagacaaggacaggaaaggcgtgctgcag
ctgagggtagcgggcgcgcccgagcctctgaccgtgacagccccgtccctgaccatcgcc
gagaacatggccgacctgatcgacggctactgccggctggtgaacggagcctcgcagtcc
ttcatcatccggccccagaaagaaggtgaacgggctttgccgtccataccgaagctggcc
aacagcgagaagcagggcgtgcggacacacgcggtctctgtgtcagagacggacgactac
gcggagatcgtggacgaggacgaggcgtacaccatgccctccaaaagctatggaatagac
gaagccagggactacgagatccagagggagcgcatcgagctcgggcgctgtatcggggaa
ggccagtttggagacgtgcaccaaggcgtgtacgtgggcccggagaacccggctttggcg
gttgccattaaaacatgtaaaaactgcacttccgacagcgtgagagagaagttccttcaa
gaagccttgacgatgcggcagttcgaccaccctcacattgtgaagctgatcggcgtcatc
acggagaatcccgtctggatcatcatggagctgtgcacgctcggagagctgaggtctttt
ctgcaagtccggaagtacagcttggatctagcgtctttgatcctgtacgcctaccagctt
agcacagctctcgcgtacctggagagcaagagatttgtgcacagagacatcgctgctcgg
aatgtcctggtgtcctccagtgactgcgtgaagttgggggactttgggttgtcccgatac
atggaagacagcacttactacaaagcttccaaaggaaaattgcctattaaatggatggct
ccagagtcgatcaattttcgacgttttacctcagctagtgacgtgtggatgttcggtgta
tgtatgtgggagatactgatgcatggtgtgaagccttttcaaggagtgaagaacaatgat
gtgatcgggcggattgagaatggggaaagattgccaatgcctccaaattgccctcccacc
ctctacagccttatgacgaaatgctgggcctatgaccccagcaggcggccccggttcact
gagctcaaagctcagctcagcaccgtcctggaggaggagaagctgcagcacgaagagcgc
atgcgaatggagtccagacggcaggtcgcggtgtcctgggactccggcgggtccgacgaa
gcgccacccaagcccagcaggcctggctacccgagcccgaggtccagtgaaggcttctac
ccgagcccgcagcacgcggtgcaggccaaccactaccaggtctccggctaccctggctcg
cacggcgtcccacccatggctggcagcatgtacccggggcaggcgcctctgctggaccag
acagactcgtggaaccacaggccgccggagatgccggtgtggcagcccggcgtggaggac
tcggccgcgcgggacctgcgcgggatcgggcaggcgttgccggcacacctgatggaggaa
cggctgatccggcagcagcaggagatggaggaggaccagcgctggctggagaaggaggag
aggttcctgaaacccgacgtgcggctctcccgaggcagcgtggaccgggaggacggcggt
ctccagggcccggctggaaaccagcacatctatcagcctgtgggaaaaccagatcctgca
gctcctccaaaaaagccaccacgccccggagcccccggccacctgggcagcctcgccagc
ctcagcagccccggggacagctacaacgagggcgtcaagccgtggaggcttcagccccag
gaaatcagccccccgcccactgccaacctggaccgctccaatgacagggtgtacgagaac
gtgacgggcctggtgaaggccgtgatcgagatgtccagcaagatccagcccgccccgccc
gaggagtacgtccccatggtgaaggacgtcggcctggccctgcgcacactgctggccacc
gtggacgagaccattcccagcctgccggccagcactcaccgagagatcgagatggcgcag
aagctgctgaactcggacctgggcgagctcatcggcaagatgaagctggcccagcagtac
gtgctgaccagcctgcagcaggagtacaagaagcagatgctcaccgccgcccacgccctg
gccgtggacgccaagaacttgctggacgtcatcgaccaggcgcggctgaagatgctgagc
cagacgagaccccactga
DBGET
integrated database retrieval system
