Pipistrellus kuhlii (Kuhl's pipistrelle): 118705482
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Entry
118705482 CDS
T07682
Symbol
MAP3K5
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5 isoform X1
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
pkl
Pipistrellus kuhlii (Kuhl's pipistrelle)
Pathway
pkl01524
Platinum drug resistance
pkl04010
MAPK signaling pathway
pkl04071
Sphingolipid signaling pathway
pkl04141
Protein processing in endoplasmic reticulum
pkl04210
Apoptosis
pkl04530
Tight junction
pkl04668
TNF signaling pathway
pkl04714
Thermogenesis
pkl04722
Neurotrophin signaling pathway
pkl04932
Non-alcoholic fatty liver disease
pkl04936
Alcoholic liver disease
pkl05010
Alzheimer disease
pkl05012
Parkinson disease
pkl05014
Amyotrophic lateral sclerosis
pkl05016
Huntington disease
pkl05017
Spinocerebellar ataxia
pkl05022
Pathways of neurodegeneration - multiple diseases
pkl05208
Chemical carcinogenesis - reactive oxygen species
pkl05417
Lipid and atherosclerosis
pkl05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pkl00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
118705482 (MAP3K5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
118705482 (MAP3K5)
04668 TNF signaling pathway
118705482 (MAP3K5)
04071 Sphingolipid signaling pathway
118705482 (MAP3K5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
118705482 (MAP3K5)
09144 Cellular community - eukaryotes
04530 Tight junction
118705482 (MAP3K5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
118705482 (MAP3K5)
09159 Environmental adaptation
04714 Thermogenesis
118705482 (MAP3K5)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
118705482 (MAP3K5)
09164 Neurodegenerative disease
05010 Alzheimer disease
118705482 (MAP3K5)
05012 Parkinson disease
118705482 (MAP3K5)
05014 Amyotrophic lateral sclerosis
118705482 (MAP3K5)
05016 Huntington disease
118705482 (MAP3K5)
05017 Spinocerebellar ataxia
118705482 (MAP3K5)
05022 Pathways of neurodegeneration - multiple diseases
118705482 (MAP3K5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
118705482 (MAP3K5)
05418 Fluid shear stress and atherosclerosis
118705482 (MAP3K5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
118705482 (MAP3K5)
04932 Non-alcoholic fatty liver disease
118705482 (MAP3K5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
118705482 (MAP3K5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pkl01001
]
118705482 (MAP3K5)
Enzymes [BR:
pkl01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
118705482 (MAP3K5)
Protein kinases [BR:
pkl01001
]
Serine/threonine kinases: STE group
STE11 family
118705482 (MAP3K5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
DRHyd-ASK
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
118705482
NCBI-ProteinID:
XP_036270178
LinkDB
All DBs
Position
Unknown
AA seq
1379 aa
AA seq
DB search
MSAEAGEGITFSVPPLAHSGLCALAESGGCWRGAAAAAEGEEDQLPPPPAGSFWNVESAA
AAPGPGCPAAAAAGSSAVRCRGNSGGGGGGRRTTVAYVINEESQGQQVGSEAEALQSLRE
ACETVGATLETLHFGKLDFGETSVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMA
NNIILYCDANSNSLQSLKEIICQKNTMCTGNYTFVPYMVTPHNKVYCCDCSFMKGLSELM
QSNFELLLGPICLPLVDRFIQLLNVAQAGSSQYFRESILNDIRKARNLYTGKELAAELAR
IRQRLDNIEVLTADIVINLLLSYRDIQEYDSIVKLVETLEKLPTFDLASHHHVKFHYAFA
LNRRNLPGDRAKALDIMIPLVQGEGQVASDLYCLVGRIYKDIFLDSNFMDTESRDNGAFW
FKKAFESEPTLQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEV
GFFLGASVLANDHLRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTTEQPVAIQEL
VDFWMDFLVEATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDENG
IHEWNFSASSIRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKRFFEMVNTITEEKG
RGVEEGDCEGDSLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRY
SQPLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQ
TIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPSTET
FTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFK
VHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLVDEFLKVSSKKKKTQPKLSALSPGS
NEYLRSISLPVPVLVEDTSSSSEYGSVSPDTELKVDPFSFKTRAKSCGEKEVKGMRTLFL
SIPDENFEDHSAPPSPEEKDSGFFMLRKDSERRATLYRILKEDQDKVVRNLMESLAQGPE
EPKLKWEHITTLITSLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFSFQDAV
NKVLRNHNIKPHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADQEDLDAEDDH
EEQPPNRIVRRPHAILEDAVATSGVSTLSSTVSHNSQNAHRSLNVQLGRMKIETNRLLEA
LVQKEKELQALLHYAIEEKDQEIKHLKLKSQPIDIPGSPAHRSTAGRNTEDSKLTDWLRE
NGADEDTISQFLAEDYSLVDVLYYVTRDDLKCLKIRGGMLCTLWKAITDFRDQQRDKQI
NT seq
4140 nt
NT seq
+upstream
nt +downstream
nt
atgagcgcggaggcgggcgagggcatcaccttctccgtgccgcccttagcgcactcgggc
ctctgcgccctggccgagagcggcggctgctggaggggagcggcggcggcggccgagggc
gaagaggaccagctgcccccgccgcccgcgggcagcttctggaacgtggagagcgccgct
gccgccccgggccccgggtgtcccgccgccgccgccgcggggagcagcgccgtccgttgc
cggggcaactccggcggcgggggaggcggccggcggaccacggtggcctatgtgatcaac
gaggagagccagggacagcaggtggggtccgaggccgaggccctgcagagcctgcgggag
gcgtgcgagacggtaggcgccacgctggagactctgcatttcgggaaactggactttggg
gagacctcggtgctggaccgtttttataatgcagatattgctgtggtggagatgagtgat
gccttccggcagccgtccttgttttaccaccttggagtgagagaaagtttcagcatggcc
aacaacatcatcctctactgcgatgcaaactcaaactccctacagtcactgaaggaaatc
atttgccagaagaatactatgtgcactgggaattacaccttcgtcccctacatggtcact
ccacacaacaaggtctactgctgtgactgcagcttcatgaaggggctgtcagagctcatg
cagtccaacttcgagctgcttctgggacccatctgcttacctcttgtggatcgtttcatt
caacttctgaacgtggcacaagctggctccagccagtatttccgggaatctatactcaat
gatatcaggaaagctcgtaatttatacactggtaaagaactggcagctgaattggcaaga
attcggcagcgattagataatattgaagtcttgacagcagatattgtcataaatctgtta
ctttcctacagagatatacaggaatatgattctattgtgaagctggtagagactttagaa
aagctgccaacctttgatttggcctcccatcatcatgtgaagtttcattatgcatttgca
ctgaacaggagaaatctccctggagatagagcaaaagctcttgatattatgattcccctg
gtgcaaggtgaagggcaagtagcttcagatttgtattgcctcgttgggcgaatctacaaa
gacatatttttggattctaatttcatggacactgagagtagagacaatggagctttttgg
ttcaaaaaggcatttgaaagtgagcctacactacagtcaggaattaattatgcagttctt
cttctggcagctggacaccagtttgaatcttcctttgagctccggaaagttggggtgaag
ctcagcagccttcttggtaaaaagggaaacttggaaaaactccagagctactgggaagtt
ggattttttctgggggccagtgtcctggccaatgaccacttgagagtcattcaagcatct
gaaaagctttttaaactgaagacaccagcatggtacctcaagtctattgtagagacaatt
ttgatatataaacattttgtgaaattgactacagagcagcctgtggctatacaggaactt
gtggacttctggatggacttcctggtcgaggccacaaagacagatgttactgtagttagg
tttccagtattaatattagaaccaaccaaaatctatcagccttcatatttgtctatcaac
aatgaagttgaggaaaagacaatatcgatttggcacgtgcttcctgatgacgagaatggt
atacatgagtggaacttcagtgcttcttccatcaggggagtgagtatttctaagtttgaa
gaacgatgctgttttctttatgtgcttcacaattctgatgatttccaaatctatttctgt
accgaacttcattgtaaaaggttttttgaaatggtgaacaccattaccgaagagaagggg
agaggtgtggaggaaggagactgtgaaggtgactccctggagtatgactacgaatatgac
gaaaatggtgacagagtcgttttaggaaaaggcacttatggaatagtctacgcaggtcga
gacctgagcaaccaagtcaggatcgccattaaggaaatcccagagagagatagcagatac
tcccagcccctgcatgaagaaatagcattgcataagcatctgaagcacaagaatattgtc
cagtatctgggttctttcagtgagaatggtttcattaaaatcttcatggagcaggttcca
ggaggaagtctttcggctctccttcgttcaaaatggggccccttgaaagacaatgagcag
acaattggattttatacgaagcaaatactggaaggattaaaatacctccatgacaatcag
atagttcaccgggatataaagggtgacaatgtgttgattaacacctacagtggcgttctc
aagatctccgacttcgggacatcaaagaggcttgctggcataaacccaagcactgaaacg
tttactggaacccttcagtacatggcaccagaaatcatagacaaaggacccagaggctat
gggaaggcagcagacatttggtccttgggttgcaccatcatcgaaatggccacagggaag
ccgcccttttatgaactgggagaaccacaagcagcgatgttcaaggtgggaatgtttaaa
gtccacccggagatcccggagtccatgtcagcagaggccaaggcgttcatcctgaagtgt
tttgaaccagaccctgacaagagagcctgtgctaacgacttgcttgttgatgagttttta
aaagtttcaagcaaaaagaaaaagacacaacctaagctttcagctctttctcctggatca
aatgaataccttaggagcatatccttgccggtccccgtcctggtggaggacacgagcagc
agcagtgagtacggctcagtttctcctgacacggagctaaaggtggaccccttctctttc
aaaacaagagccaaatcctgcggagaaaaggaagtgaaaggaatgcggaccctctttttg
agcattccagatgagaactttgaagatcacagtgctcccccttctcccgaggagaaggac
tccgggttctttatgctgaggaaggacagcgagcggcgggccaccctctacaggatcctg
aaggaagaccaggacaaagttgtgagaaacttaatggaatctttggctcaggggcccgaa
gaacctaagctaaagtgggagcacatcacaaccctcatcacaagcctcagagaatttgtg
agatccaccgaccgaaaaatcatagccaccactctgtccaagctgaagctggagctggac
ttcgacagccatggcatcagtcaggtccaggtggtgctcttcagcttccaggatgctgtg
aataaagttcttcggaatcataacatcaagccacactggatgtttgccttagacagtatc
atccggaaggcagtgcagacggccattaccattctggttccagaactgaggccccatttt
agccttgcatctgagagtgatacagcagatcaggaagacttggatgcagaagatgaccat
gaggagcagcctccgaatcgaattgtccgaagacctcatgccatccttgaagatgctgtg
gctacctcaggggtgagcacgctcagttctactgtatcccacaattcccagaatgctcac
cggtcactgaatgtacagcttggaagaatgaaaatagaaactaatagattactggaagca
ttggttcagaaagagaaagaattacaagcactccttcattatgctattgaagaaaaggac
caagaaattaaacacctgaagcttaagtcccagccaatcgatattcctggatcgcctgca
catcgctcaactgctggcagaaatactgaagattctaaactcactgactggctgagagaa
aatggagctgatgaagacactataagtcagtttttggctgaggattattcactggtggat
gttctctactatgttacacgtgatgacttaaaatgcctgaaaataaggggagggatgctc
tgcacactgtggaaggccatcactgactttcgggaccagcagagagacaaacagatttga
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integrated database retrieval system
