Pipistrellus kuhlii (Kuhl's pipistrelle): 118708400
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Entry
118708400 CDS
T07682
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
pkl
Pipistrellus kuhlii (Kuhl's pipistrelle)
Pathway
pkl04120
Ubiquitin mediated proteolysis
pkl04144
Endocytosis
pkl04330
Notch signaling pathway
pkl04668
TNF signaling pathway
pkl04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
pkl00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
118708400 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
118708400 (ITCH)
04668 TNF signaling pathway
118708400 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
118708400 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
118708400 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pkl04131
]
118708400 (ITCH)
04121 Ubiquitin system [BR:
pkl04121
]
118708400 (ITCH)
Enzymes [BR:
pkl01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
118708400 (ITCH)
Membrane trafficking [BR:
pkl04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
118708400 (ITCH)
Ubiquitin system [BR:
pkl04121
]
Ubiquitin ligases (E3)
HECT type E3
118708400 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
118708400
NCBI-ProteinID:
XP_036275659
LinkDB
All DBs
Position
Unknown
AA seq
862 aa
AA seq
DB search
MSDSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPVTVIVTPMSKLHFRVWSHQTLKSDVLLGTATLDIYETLKSNNMKFEKVVVTL
QLVGDKEPTETIGDLSICLDGLQLESEVVTNGEATCAESASQNDDGSRPKEETRVNTNGS
DDPEDAGSGENRKVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTNTNSNTSEGATSGLIIPLTISGGSGPRPLNPVPQAPLPPGWEQRVDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFATSQNKEFDPLGPLPPGWEKRTDGNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKFQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHTIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggatcacagcttgggtcaatgggtagcctgaccatgaaatcacaactt
cagatcactgtcatttcagcaaaacttaaagaaaataaaaagaattggtttggaccaagt
ccttacgtggaagttacagtagatggacagtcaaagaagacagaaaaatgtaacaataca
aacagtcccaaatggaagcaacccgttacagttatcgtcacccctatgagtaaattacat
tttcgcgtgtggagtcaccagacactgaaatctgatgttttattgggaactgctacacta
gatatctatgaaacattgaagtcaaacaatatgaaatttgagaaagtagttgtgacttta
cagcttgtaggtgacaaagaaccaacagagacaataggagacttgtcaatttgtctagat
gggctgcaattagaatctgaagttgttaccaacggtgaagctacatgtgcagaaagtgct
tcacagaatgatgatggctccaggcccaaggaggagacaagagtgaacacaaatggatca
gatgaccccgaggatgcagggtctggtgaaaataggaaggtcaatgggaataattctcca
tcgctctcaaacggcggctttaagccttctagacctccaagaccttcgcgaccacctcca
cctaccccgcggagaccagcttccgttaatggttcaccttctgccacttctgaaagtgat
ggctctagtacaggttctctgcctccaacaaatacaaattcaaatacatctgagggagca
acatctggattaataattcctcttactatatctggaggctcgggccctagaccattaaat
cctgtaccccaagctccactaccacctggttgggagcagagagtggaccagcatgggcga
gtttactatgtagatcatattgaaaaaagaacaacgtgggatagaccagaacctctacct
cctggctgggaacgcagggttgacaacatgggacgtatttattatgttgaccatttcaca
agaacaacaacgtggcagaggccaacattggagtccgtccggaactatgaacagtggcag
ctccaacgtagtcagcttcaaggagcaatgcagcagtttaatcagagattcatttatggg
aatcaagatttgtttgcaacatcacaaaataaagaatttgatcctcttggtcccctccca
cctggatgggaaaagagaacggatggcaatggtagagtgtattttgtcaatcacaacact
cgtattacacaatgggaagaccccagaagtcaaggtcaattaaatgaaaagcccttacct
gaaggctgggaaatgagattcacagtggatggaattccttattttgtggaccacaatagg
agaacaaccacctatatagatccacgcactggaaaatctgccctagacaatggaccccag
atagcctacgtacgggactttaaggcaaagtttcagtatttccggttctggtgtcagcaa
ctggccatgccacagcacataaagattacagtgacaagaaaaacattgtttgaggattcc
tttcagcagataatgagcttcagtccccaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagggaatggttctttcttttgtca
catgaagtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataactactgc
ttgcagataaaccccgcttcttatatcaatccagatcacctgaaatattttcgttttatt
ggcagatttattgccatggctcttttccatgggaaattcatagatacaggtttttccttg
ccattctacaagcgtatcttgaacaaaccagttgggctcaaggacttagaatctattgat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaggaatgtggtttg
gaaatgtacttctccgtcgataaagaaattttaggtgaaatcaagagtcatgatttgaaa
cccaatggtggcaatattcttgtaacagaagaaaataaagaggaatatatcagaatggta
gctgaatggaggttgtctcgaggtgttgaagaacagacacaagctttctttgagggtttt
aatgaaattcttccccagcagtatttgcaatactttgatgcaaaggagttagaggtcctt
ttatgcggaatgcaagagattgatttgaatgactggcaaagacataccatctaccgtcat
tatactaggacaagcaaacaaataatgtggttttggcagtttgttaaagaaatcgataat
gagaagagaatgagacttctacagtttgttactgggacctgccgattaccagttggagga
tttgctgacctcatggggagcaacggacctcaaaaattctgcattgaaaaagttgggaaa
gaaaattggttacccagaagtcatacctgttttaaccgcctggacctaccaccctataag
agctatgagcaactgaaggaaaagctgttatttgccattgaagaaacagaaggatttgga
caagagtaa
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