Pipistrellus kuhlii (Kuhl's pipistrelle): 118709201
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Entry
118709201 CDS
T07682
Symbol
IRS1
Name
(RefSeq) insulin receptor substrate 1
KO
K16172
insulin receptor substrate 1
Organism
pkl
Pipistrellus kuhlii (Kuhl's pipistrelle)
Pathway
pkl04022
cGMP-PKG signaling pathway
pkl04068
FoxO signaling pathway
pkl04081
Hormone signaling
pkl04140
Autophagy - animal
pkl04150
mTOR signaling pathway
pkl04151
PI3K-Akt signaling pathway
pkl04152
AMPK signaling pathway
pkl04211
Longevity regulating pathway
pkl04213
Longevity regulating pathway - multiple species
pkl04722
Neurotrophin signaling pathway
pkl04910
Insulin signaling pathway
pkl04920
Adipocytokine signaling pathway
pkl04923
Regulation of lipolysis in adipocytes
pkl04930
Type II diabetes mellitus
pkl04931
Insulin resistance
pkl04932
Non-alcoholic fatty liver disease
pkl04935
Growth hormone synthesis, secretion and action
pkl04960
Aldosterone-regulated sodium reabsorption
pkl05010
Alzheimer disease
pkl05206
MicroRNAs in cancer
pkl05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
pkl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
118709201 (IRS1)
04022 cGMP-PKG signaling pathway
118709201 (IRS1)
04151 PI3K-Akt signaling pathway
118709201 (IRS1)
04152 AMPK signaling pathway
118709201 (IRS1)
04150 mTOR signaling pathway
118709201 (IRS1)
09133 Signaling molecules and interaction
04081 Hormone signaling
118709201 (IRS1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
118709201 (IRS1)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
118709201 (IRS1)
04923 Regulation of lipolysis in adipocytes
118709201 (IRS1)
04920 Adipocytokine signaling pathway
118709201 (IRS1)
04935 Growth hormone synthesis, secretion and action
118709201 (IRS1)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
118709201 (IRS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
118709201 (IRS1)
09149 Aging
04211 Longevity regulating pathway
118709201 (IRS1)
04213 Longevity regulating pathway - multiple species
118709201 (IRS1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
118709201 (IRS1)
09164 Neurodegenerative disease
05010 Alzheimer disease
118709201 (IRS1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
118709201 (IRS1)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
118709201 (IRS1)
04932 Non-alcoholic fatty liver disease
118709201 (IRS1)
04931 Insulin resistance
118709201 (IRS1)
BRITE hierarchy
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Ortholog
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Motif
Pfam:
IRS
PH
PH_11
Motif
Other DBs
NCBI-GeneID:
118709201
NCBI-ProteinID:
XP_036277017
LinkDB
All DBs
Position
Unknown
AA seq
1254 aa
AA seq
DB search
MASPADAEGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP
KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKSH
HDGAAAPGTGTGGGGGGGGGGGSCSGSSGLGEAGEDLSFFGDCNPGPAFKEVWQVVLKPK
GLGQTKNLIGIYRLCLTSKTISFVKLNTEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVT
GPGEFWMQVDDSVVAQSMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNN
PPPSQVGLTRRSRTESITATSPASLVGGKQGSFRVRASSDGEGTMSRPASVDGSPVSPST
NRTHAHRHRGGCSRLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLFPR
RSSASVSGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGG
KGAASTLAAPNGHYILPSRGGNGHRYLPAAGAGVGTTNSAQAGEDAAGAAAELDNRFRKR
THSAGTSPTISHQKTPSQSSVASIEEYTEMMPACPPGGGSGGRPPSHRHSAFLPTQSYPE
EGLDMLPLERRGGGQGRPDTSSLHTDDGYMPMTPGVAPVPGSRKGSGDYMPMSPKSVSSP
QQIINPLRRHPQRVDPNGYMMMSPSGSSSPDTAGGPSSSSSNSAAPPRSSYGKPWTNGVG
GHPSHPLPPSKLPPESSGGKLLPGTGDYMNMSPVGDSSTSSPSDCYCGPEDPQNKPVLSY
YSLPRSFKHTQRPGDPEEAARHQHLRLSSSSGRLLYAAAAEDSSPSTSNDSLGGGYSGGK
PEPSLPPQLHHQVLQTHLPRKVDSAAQTNSRLARPTRLSLGDPKASTLPRAREQQQPAAL
LLPPEPKSPGEYVNIEFGSDQPGYLSGPVASHSSPSVRCPSQLQPAPREEGAGTEEYMNM
DLGPGRRAPPWQESPAVQPSRVGPAPPGTASACRPTRAVPSTRGDYMTMQVGCPHPSYVD
TSPVAPVSYADIRTGVVEEGSLPGAAAAAPSSSSTASASPTAPQGAGELVAPQGSGGTSA
FTRVNLSPSGNQSAKVIRADPQGCRRRHSSETFSMPSAPRAGNTVPSAGAAVGGSSGGGS
SSIEDVKRHSSASFENVWLRPGELGGAPKEQAPVRGAAGGLENGLNYIDLDLVKDFKQRP
QEHRPQGQRPQPPTRHHHHHHPPGSSESSSSSRSREDVSAYASISFQKQPEDLQ
NT seq
3765 nt
NT seq
+upstream
nt +downstream
nt
atggcgagccccgcggacgccgagggcttctcggacgtgcgcaaggtgggctacctgcgc
aaacccaagagcatgcacaagcgcttcttcgtgctgcgggcggccagcgaggcggggggc
ccggcgcgcctggagtactacgagaacgagaagaagtggcggcacaagtcgagcgccccc
aaacgctcgatccccctcgagagctgcttcaacatcaacaagcgggccgactccaagaac
aagcacctggtggccctctacacccgggacgagcacttcgcgatcgcggcggacagcgag
gccgagcaggacagctggtaccaggccctcctgcagctgcataaccgcgccaagagtcac
cacgacggggccgcggcccccgggaccgggacggggggcggcggcggcggcggcggcggc
gggggcagctgcagcggcagctccggcctgggcgaggccggggaggacctgagcttcttc
ggcgactgcaaccccgggcccgccttcaaagaggtctggcaggtggtcttgaaacccaag
ggcctgggccagacaaagaacctgatcggcatctaccgcctctgcctgaccagcaagacc
atcagcttcgtgaagctgaacacggaggcggccgccgtggtgctgcagctgatgaacatc
cggcgctgcgggcactcggagaacttcttcttcatcgaggtgggccgctccgccgtcacc
gggcccggggagttctggatgcaggtggacgactcagtggtggcccagagcatgcacgag
accatcctggaggccatgcgggccatgagcgacgagttccggcctcgcagcaagagccag
tcctcctccaactgctccaaccccatcagcgtgcccctgcgcaggcaccacctcaacaac
ccgccgcccagccaggtggggctgacccgccgctcccgcaccgagagcatcacggccacc
tcgcccgccagcctggtgggcggcaagcagggctccttccgcgtccgcgcctccagcgac
ggcgaaggcacgatgtcccgcccggcctcggtggacggcagccccgtgagccccagcacc
aacaggacgcacgcccaccgccatcgggggggctgctcgcggctgcaccccccgctcaac
cacagccggtccatccccatgccttcctcccgctgctcgccctcggccaccagccccgtc
agcctgtcctcgagcagcaccagcgggcacggctccacctcggactgccttttcccgcgg
agatccagcgcttccgtgtccggctccccgagcgacggcggcttcatctcctccgacgag
tacggctccagcccctgcgatttccggagctccttccgcagtgtcaccccggattccctg
ggccacaccccgccggcccgcggggaggaggagctgagcaactatatctgcatgggaggc
aagggggccgcctccacgctcgccgcccccaatggccactacatcttgccttctcggggt
ggcaatggccaccgctacctcccggccgctggcgctggcgtgggcaccacgaactcggcc
caggctggggaggacgcggccggtgctgctgccgagctggacaatcggtttcgcaagcgg
actcactccgctggcacatcccccaccatctcccaccagaagaccccgtcgcagtcctcc
gtggcttccattgaggagtatacagagatgatgcccgcctgcccaccaggagggggcagt
ggaggccggccgcccagccaccggcactccgccttcctgcccacccagtcctacccggag
gagggtctggacatgctccccctggagcgccgcggagggggccaaggccgccccgacacc
tccagcctccacacggatgatggctacatgcccatgaccccaggggtggccccggtgcca
ggcagccggaaaggcagcggggactacatgccgatgagccccaagagtgtgtcttccccg
cagcagatcatcaaccccctcagacgccatccccagagggtggaccccaatggctacatg
atgatgtccccaagtggcagctcctccccggacactgcgggtgggcccagcagcagcagc
agcaacagtgccgcccctcctcggagtagctatgggaagccctggacaaatggggttggg
ggccacccctcccacccgctgccaccctccaaactacccccggagagcagcggtgggaag
ctcttgcctggtacaggcgactacatgaacatgtcaccggtgggggactccagcaccagc
agcccctccgactgctactgcggccccgaggacccccagaacaagccggtgctctcctac
tactcattgccaaggtccttcaagcacacccagcgcccgggggacccggaggaggccgcc
cggcaccagcacctgcgcctttcctccagctctggccgccttctctatgctgcagccgcc
gaagattcctctccctccaccagcaacgacagcctgggtgggggatactccggggggaag
cccgagcccagcctcccgcctcaactccaccatcaggtcctgcagacccatctgcctcga
aaggtggactcggctgcgcagaccaacagccgcctggctcggcccacgaggctttccctg
ggggaccccaaggccagcaccttacctcgggctcgagagcagcagcagcccgcggccctc
ctgctccctccggagcccaagagcccgggggaatatgtgaatatagagtttgggagtgat
cagcctggctacttatccggtcccgtggcatcccacagctcaccttccgtcaggtgtccg
tcccagctgcagccagctcccagggaggaaggggctggcaccgaagagtacatgaacatg
gacctagggcctggccggagggcgcccccctggcaggagagccctgcggtccagccgagc
agagtgggccctgcacctccagggaccgccagcgcatgcaggcctacccgggcagtgcct
agcactcggggtgactacatgaccatgcaggtgggttgtccccatccgagctatgtggac
acctctccagtcgcccctgtcagctatgctgatatccggacaggcgttgtggaggagggg
agccttcccggggctgcagcggctgctccctcctcttcctcgacagcctctgcttccccc
actgcgcctcaaggagcaggggagctggtggccccgcaggggtccgggggcacgagtgcc
ttcacccgggtgaacctcagtcccagtggcaaccagagtgccaaagtgatccgcgcagac
ccgcaagggtgccggaggcggcatagctccgagaccttctccatgcctagcgccccccgg
gccggcaacacggtgccctcagcgggggctgcagtagggggcagcagtggcggcggcagc
agcagcattgaggatgtgaaacgtcacagctctgcttcctttgagaacgtgtggctgagg
cctggggagctcgggggagcacccaaagagcaggctccagtgcgaggggctgcaggcggt
ttggagaatggtctgaactatatagacctggatttggtcaaggacttcaaacagcgcccc
caggagcaccgccctcaggggcagcgtccccagcccccaacccgtcatcatcatcatcat
catcctccaggtagcagtgagagcagctcctccagccgctccagggaggatgtaagcgcc
tatgccagcatcagtttccagaagcagccagaggacctccagtag
DBGET
integrated database retrieval system
