KEGG   Pipistrellus kuhlii (Kuhl's pipistrelle): 118727130
Entry
118727130         CDS       T07682                                 
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase-like
  KO
K00070  3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
Organism
pkl  Pipistrellus kuhlii (Kuhl's pipistrelle)
Pathway
pkl00140  Steroid hormone biosynthesis
pkl01100  Metabolic pathways
pkl04913  Ovarian steroidogenesis
pkl04925  Aldosterone synthesis and secretion
pkl04927  Cortisol synthesis and secretion
pkl04934  Cushing syndrome
Module
pkl_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
pkl_M00110  C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
pkl_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:pkl00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    118727130
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    118727130
   04925 Aldosterone synthesis and secretion
    118727130
   04927 Cortisol synthesis and secretion
    118727130
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    118727130
Enzymes [BR:pkl01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.145  3beta-hydroxy-Delta5-steroid dehydrogenase
     118727130
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.3  Transposing C=C bonds
    5.3.3.1  steroid Delta-isomerase
     118727130
SSDB
Motif
Pfam: 3Beta_HSD Epimerase NAD_binding_4 GDP_Man_Dehyd Polysacc_synt_2 NAD_binding_10 RmlD_sub_bind NmrA KR
Other DBs
NCBI-GeneID: 118727130
NCBI-ProteinID: XP_036308457
LinkDB
Position
Unknown
AA seq 373 aa
MAGWSCLVTGAGGFLGQRIIRLLVEERELQEIRALDKAFRPELQEEFSKLQSQSKLTLLE
GDILDEQFMKRACQGTSAVIHAASVIDVFNAIPRETIMDVNVKGTQILLEACAQASVPIF
IYTSTIEVAGPNSYWEVVRDASEDQRLESTWSAPYPHSKKLAEEAVLAANGWALRNGGTL
STCALRPMYIYGEGSPFLRGFVAQALRNHGTLPHNSKHSLVNPVYVGNAAWAHVLALRAL
RDPERAAGVGGQFYYIADDTPPQSYDQLNYALGGEWGFRLDARRGLPVLLQYWLGFLLEM
VSLLLRPVCRYRPPFNRHTVTLLNSVFTFSYKKAQRDLGYKPLFSWEQAQQNTAAWIGAL
VKRHREAGRAKAR
NT seq 1122 nt   +upstreamnt  +downstreamnt
atggccgggtggagctgcctcgtgacgggcgcaggaggattcctgggccagaggatcatc
cgcttgctggtggaggagagagagctgcaggagatccgggcgctggacaaagccttcaga
ccagaattgcaggaggaattctctaagctccagagccagagcaagctgaccttgctggaa
ggagacattctggatgagcagttcatgaagagagcctgccagggcacctcggctgtcatt
cacgccgcctccgtcattgacgtcttcaatgccattccgagagagaccatcatggatgtc
aacgtgaaaggcacccagatcctgctggaggcctgcgcccaggccagcgtgcccatcttc
atctacaccagcaccatcgaggtggcggggcccaactcctactgggaggtcgtccgggac
gccagcgaggaccagcgcctggagagcacgtggtcggccccgtacccgcacagcaagaag
ctggccgaggaggccgtgctggccgccaacggctgggccctcaggaacggcggcaccctg
tccacgtgcgccctgcggcccatgtacatctacggggaagggagcccgttcctgcgcggc
ttcgtggcccaggccctgcggaaccacggcaccctgccccacaacagcaagcactccttg
gtcaaccccgtgtacgtgggcaacgcggcctgggcccacgtgctggccctgcgggccctg
cgggaccccgagcgggctgcgggcgtcgggggacagttctactacatcgccgacgacacg
ccgccccagagctacgaccagctcaactacgcgctgggcggggagtggggcttccgcctg
gacgcccgcaggggcctgcccgtgctgctgcagtactggctgggcttcctgctggagatg
gtgagcctcctgctcaggcccgtgtgccggtaccggccccccttcaaccgccacacggtg
accctgctcaacagcgtcttcaccttctcctacaagaaggcgcagcgggacctgggctac
aagccgctcttcagctgggagcaggcccagcagaacaccgcggcgtggatcggcgccctg
gtgaagcggcaccgggaagccgggagagccaaggcccgctga

DBGET integrated database retrieval system