KEGG   Pipistrellus kuhlii (Kuhl's pipistrelle): 118730275
Entry
118730275         CDS       T07682                                 
Symbol
CDK4
Name
(RefSeq) cyclin-dependent kinase 4
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
pkl  Pipistrellus kuhlii (Kuhl's pipistrelle)
Pathway
pkl01522  Endocrine resistance
pkl04110  Cell cycle
pkl04115  p53 signaling pathway
pkl04151  PI3K-Akt signaling pathway
pkl04218  Cellular senescence
pkl04530  Tight junction
pkl04660  T cell receptor signaling pathway
pkl04933  AGE-RAGE signaling pathway in diabetic complications
pkl04934  Cushing syndrome
pkl05160  Hepatitis C
pkl05162  Measles
pkl05163  Human cytomegalovirus infection
pkl05164  Influenza A
pkl05165  Human papillomavirus infection
pkl05166  Human T-cell leukemia virus 1 infection
pkl05167  Kaposi sarcoma-associated herpesvirus infection
pkl05169  Epstein-Barr virus infection
pkl05200  Pathways in cancer
pkl05203  Viral carcinogenesis
pkl05212  Pancreatic cancer
pkl05214  Glioma
pkl05218  Melanoma
pkl05219  Bladder cancer
pkl05220  Chronic myeloid leukemia
pkl05222  Small cell lung cancer
pkl05223  Non-small cell lung cancer
pkl05224  Breast cancer
pkl05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:pkl00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    118730275 (CDK4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    118730275 (CDK4)
   04115 p53 signaling pathway
    118730275 (CDK4)
   04218 Cellular senescence
    118730275 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    118730275 (CDK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    118730275 (CDK4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118730275 (CDK4)
   05203 Viral carcinogenesis
    118730275 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    118730275 (CDK4)
   05225 Hepatocellular carcinoma
    118730275 (CDK4)
   05214 Glioma
    118730275 (CDK4)
   05220 Chronic myeloid leukemia
    118730275 (CDK4)
   05218 Melanoma
    118730275 (CDK4)
   05219 Bladder cancer
    118730275 (CDK4)
   05224 Breast cancer
    118730275 (CDK4)
   05222 Small cell lung cancer
    118730275 (CDK4)
   05223 Non-small cell lung cancer
    118730275 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    118730275 (CDK4)
   05160 Hepatitis C
    118730275 (CDK4)
   05164 Influenza A
    118730275 (CDK4)
   05162 Measles
    118730275 (CDK4)
   05163 Human cytomegalovirus infection
    118730275 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    118730275 (CDK4)
   05169 Epstein-Barr virus infection
    118730275 (CDK4)
   05165 Human papillomavirus infection
    118730275 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    118730275 (CDK4)
   04934 Cushing syndrome
    118730275 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    118730275 (CDK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pkl01001]
    118730275 (CDK4)
Enzymes [BR:pkl01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     118730275 (CDK4)
Protein kinases [BR:pkl01001]
 Serine/threonine kinases: CMGC group
  CDK family
   118730275 (CDK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kdo Haspin_kinase ABC1
Other DBs
NCBI-GeneID: 118730275
NCBI-ProteinID: XP_036314019
LinkDB
Position
Unknown
AA seq 303 aa
MATLRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATSRTDRETRVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGIVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSAYATPVDLWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEEDWPR
DVSLPRGAFPPRGPCPVQSVIPEMDKSGAQLLLEMLTFNPHKRISAFRALQHPYLQKEDG
DPE
NT seq 912 nt   +upstreamnt  +downstreamnt
atggctacccttcggtatgagccagtggctgagattggtgttggtgcctacgggacggtg
tacaaggcccgtgatccacacagtggccactttgtggccctcaagagcgtgagagtcccc
aatggaggaggtggcggagggggccttcccatcagcacagttcgcgaagtggccttactg
aggcggctggaggcttttgagcatcccaacgttgtccggctgatggatgtctgtgctacc
tcccgaactgaccgggagaccagagtgaccctggtgtttgagcatgtggaccaagaccta
cggacgtatctggacaaggcacccccaccaggcttgccagtggagaccatcaaggatctg
atgcgccagtttctaagaggcctggattttcttcatgccaattgcattgttcatcgagac
ctgaagccagagaatattctggtgacaagtggcgggatagtcaagctggccgactttggc
ctggccagaatctacagctaccagatggcacttacacctgtggttgttacgctctggtac
cgtgctccggaagttcttctgcagtctgcatacgcaacacctgtggacctgtggagtgtt
ggctgcatctttgcagagatgtttcgtcgaaagcctctcttctgcggaaactctgaagct
gaccagttgggcaaaatctttgacctgattgggctgcctcctgaggaggattggccccga
gatgtgtctctaccccgaggagccttcccccccagaggaccctgccccgtgcagtcggtg
ataccggagatggataagtctggagcacagctgctgctggagatgctgacttttaaccca
cacaagcggatctctgccttccgagccctgcagcacccttacctacaaaaggaagacggt
gacccagagtga

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