KEGG   Plectropomus leopardus (leopard coralgrouper): 121946685
Entry
121946685         CDS       T07454                                 
Symbol
plcg1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
  KO
K01116  phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
Organism
plep  Plectropomus leopardus (leopard coralgrouper)
Pathway
plep00562  Inositol phosphate metabolism
plep01100  Metabolic pathways
plep04012  ErbB signaling pathway
plep04020  Calcium signaling pathway
plep04070  Phosphatidylinositol signaling system
plep04370  VEGF signaling pathway
Module
plep_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:plep00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    121946685 (plcg1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    121946685 (plcg1)
   04370 VEGF signaling pathway
    121946685 (plcg1)
   04020 Calcium signaling pathway
    121946685 (plcg1)
   04070 Phosphatidylinositol signaling system
    121946685 (plcg1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:plep04131]
    121946685 (plcg1)
Enzymes [BR:plep01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     121946685 (plcg1)
Membrane trafficking [BR:plep04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    121946685 (plcg1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    121946685 (plcg1)
SSDB
Motif
Pfam: PI-PLC-X SH2 PI-PLC-Y EF-hand_PLCG2 PH SH3_1 C2 EF-hand_PLCG1 SH3_9 PH_12 SH3_2 GDPD EF-hand_7 EF-hand_6 Mcp5_PH
Other DBs
NCBI-GeneID: 121946685
NCBI-ProteinID: XP_042347303
LinkDB
Position
8:21059172..21100638
AA seq 1316 aa
MAGTSGFFSNGPVPWMDNDTEMNNLYRDLELGTVLTLFYSKKSQRPERRTFQVKLETRTI
IWTRGTDKIEGEIDIREIKEIRPGQKSRDFERYVEDSAARLDQAHCFVILYGTEFRLKSL
SLAATSDEEMTMWVKGLNWLVADTLKSPTPLQIERWLRKQFYAVDRNREDRISCKDLKSM
LSQVNYRVPNMRFLREKLPDSELRNGDVSFSQFAQLYRSLMFDAQKNMEIPFIQRFIDRP
EQRISLDDFKGFLLESQKEMWATDNNKVQEFMFSYLKDPLREVEQPYFHQDEYLTYLFSK
ENTIWESSLDQVCPDNMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIE
LDCWDGPDGMPVIYHGHTLTTKIKFCDVLTTIKEHAFVTSDYPIILSIEDHCSIVQQRNM
ATYFKKVFGDMLLTKAVDIAADGLPSPNQLKRKILIKHKKLAEGSAYEEVSTSTPYSEND
ISNSIKNGILYLEDPINHEWYPHFFVLTSSKIYYSEETSSNQGNDDEEEHREVSNGMDQH
VTEKWFHGKLGAGRDGRQIAERLLSEYCLETGAPDGSFLVRESETFVGDYTLSFWRSGRV
QHCRIHSRQEAGSPKFYLTDNLVFDTLFALINHYQQVALRCNEFEMKLTEPVPQTNAHES
KEWYHANLSRSHAENMLMRVPRDGAFLVRKRAEPNSFAISFRAEGKIKHCRVQQEGQTVV
LGTSEFDSLVDLISYYEKHPLYRKMKLRYPINEDTLEKIGTDEPDYGSLYEGRNPGFYVE
ANQMPTFKCTVKAMYEYKAQRDDELSFVKNAIISNVDKQEGGWWKGDCGGKKQLWFPANY
VEEVSPSAAEPDRTEMTENSPLGDLLRGSVDVSSCQIVVRPEGKGSRPHVFSLVPNPSMR
TGQVLDVAASSQEELKEWVFKIREVTMTSEAKLEEGKMMERRKKIALELSDLVIYCRPVP
FDEDKIGTERACFRDMSSFPETKAEKYVNKIKGKKFLQYNRLQLSRIYPRGQRLDSSNYD
PLPMWLCGSQLVALNFQTADKPMQMNQALFMLNGKSGYVLQPPIMRDDNFDPFDRHTLRG
LEQVTLEIEVLGARHLPKHGRGIVCPLIEIEVCGAEYDSAKQKTDSEADNGLNPTWPRKS
FQFVVCNSAFAFLRFVVYEIDMFSDQNFLAQATFPIHGLKTGYRSVPLKNSYNEDLELAS
LLVHMDIIRGRDENGEVLSPFLAVGATSMSASTQAGRERLGELNSVSSTSSNMSPVPQSP
AQAMAYRGREGSFESRYQSPLEDFRVPQEALLDHMDPQNRQTRMLRRTRVGGENRV
NT seq 3951 nt   +upstreamnt  +downstreamnt
atggctgggacctcgggcttcttttccaacggacccgttccgtggatggacaatgacacg
gagatgaacaacctgtaccgagacctggagctggggacagtactgacactgttttattct
aagaagtcccagcggccagagagacgaacatttcaagtcaagctggagaccaggactatt
atctggactcggggcacggataaaatagaaggagagattgacattcgagagatcaaggag
atccgtcctggacaaaagtcacgggactttgagcgctatgtggaggactcggcagcgagg
ctggaccaggctcactgctttgtcatcctgtatggcacggagtttcgccttaaatccctc
agcctagcagcaacgtctgatgaggagatgaccatgtgggtgaaggggttaaactggctt
gttgccgacacactgaagtctccgacaccgctccagatagagagatggttacgaaagcag
ttctacgctgttgatcgcaacagagaagacaggatatcctgtaaggatctgaagagcatg
ctgagccaggtcaactacagggtgcccaacatgaggttcctccgagagaaacttccggac
tccgagttgaggaatggagacgtgtccttcagccagtttgcgcagctctatcgcagcctc
atgtttgatgctcagaaaaacatggagatcccatttatacagaggttcattgacagacca
gaacagaggatctccctcgacgacttcaagggcttcctcctcgagtctcaaaaggaaatg
tgggccacagacaacaacaaagttcaagagtttatgttcagctacctgaaagaccccctg
agggaagtggagcaaccttatttccaccaagacgagtacctgacgtacctgttctccaaa
gagaacaccatatgggagtcctcgctggaccaggtgtgtcctgacaatatgaacaacccc
ctgtcccactactggatctcctcttcgcacaacacctacctgacgggagaccagttttcc
agtgagtcgtccctggaggcgtacgctcgctgtctgaggatgggctgccgctgcattgaa
ctggactgctgggatggtccagatggaatgccagtcatctaccacggacacaccctcacg
acaaaaatcaagttttgcgatgtcttgaccaccatcaaagagcatgccttcgtcacatct
gactatcccatcatcttgtccattgaggaccactgtagtattgtgcagcagagaaatatg
gccacttactttaagaaggtgtttggagacatgctgctgaccaaggcggtggatattgcg
gcagacgggctgccctcacccaaccagctcaagaggaagattctcatcaagcataagaag
cttgcagaaggcagtgcctatgaggaggtgtccacctccactccgtactcggagaacgat
atcagcaactccatcaaaaatggcatcctgtacctggaagaccccattaatcatgagtgg
taccctcatttctttgtcctgactagcagtaagatctactactcagaggagacctccagt
aaccagggcaacgatgatgaagaggagcacagagaggtgtccaacggtatggaccagcac
gtgacagagaaatggttccatgggaagttgggagcagggcgggacgggaggcagatagcc
gagaggttactgtcggagtactgcctggagactggagctccagatggctccttcctggtc
cgagagagcgagacctttgtgggagactacacgctgtctttctggcgttcagggcgggtg
cagcactgtcgtatccactctcgtcaggaggcaggcagcccgaagttctacctgactgac
aacctggtgttcgacacgctctttgccctgatcaaccactaccagcaggtggcgctgcgc
tgcaacgagtttgagatgaagctgactgagccggtgcctcagaccaacgctcatgagagc
aaagaatggtaccatgccaacctctccaggagccatgcagaaaacatgctaatgagggta
cctcgtgatggggctttcctcgtgaggaagagggcggaacccaactcgtttgccatttcc
ttcagggctgagggaaagataaagcactgtcgcgtgcagcaggaaggtcagaccgtggtg
ctgggcacctcagagtttgacagcctcgtagatctcatcagctactatgagaagcaccct
ctgtaccgcaaaatgaaactgcggtatcccatcaatgaggacacactggagaagataggc
accgatgagccagactatgggtcactgtacgagggcaggaatccaggcttttatgtggag
gccaaccaaatgccaacatttaagtgcactgtgaaagccatgtacgagtataaagcccag
agagacgatgagctctccttcgttaagaacgccattatctctaatgtggacaaacaggaa
ggaggatggtggaagggtgactgtggagggaagaagcagctgtggtttcctgctaattac
gtggaggaggtcagtccgtccgcggcggagcctgatagaaccgagatgacagaaaacagc
cctctgggagatctgctgagaggaagtgtggacgtgtcttcctgtcagattgttgtgcgt
cctgaagggaaaggcagtaggcctcatgtcttctccttagtgccaaacccttccatgcgg
acgggccaggtgctggatgtcgccgccagcagccaggaggaactcaaggaatgggtgttc
aagatccgtgaggttacaatgacctcagaggccaagctggaggagggaaagatgatggag
aggaggaagaagattgcactagaattatccgacctggtcatctactgtaggcctgtgccc
tttgatgaagacaaaattggcacagagcgggcctgtttcagggacatgtcatccttcccc
gagaccaaggcagagaaatacgtcaacaagatcaaagggaagaagttcttgcagtacaat
cgactgcagctgtccaggatctaccccagaggccagagactagactcctccaactacgac
cctctgcccatgtggctctgtgggtcccagctggtagcgctcaactttcagacagcagac
aaacccatgcagatgaaccaggctctgttcatgctaaacggaaagagtggctacgtcctt
cagccgcccatcatgagggacgacaactttgatcccttcgacagacatacgctgcgaggc
ctagaacaggtcacgctagagattgaggttttgggcgcccggcacttgcccaagcacggg
cgtggcatagtttgtcctctgattgagattgaggtgtgcggggcagaatacgacagtgcc
aagcaaaaaactgactctgaagctgataacggtctgaaccccacgtggccccgaaaatca
ttccagttcgtagtatgcaattctgcctttgccttcctgcgctttgtggtttatgagatt
gacatgttcagtgaccaaaacttcctggcacaggcaactttccccattcatggcctcaag
acaggttaccggtcagtacctcttaagaacagctacaacgaggatctggagttggcctct
ctgttagtccacatggacatcatcagaggaagggatgaaaatggcgaggtcttgagcccg
ttccttgcagtcggggccacatcaatgtcagcctctacccaagcagggcgggaacgtttg
ggggaattgaactccgtgtcttcgacctcctccaacatgtctcctgtgccccagtcgccg
gcccaggccatggcctacagggggagggagggctccttcgagtcccgctaccagtcccct
ctagaggacttcagggtgccccaggaggcactgttggatcacatggacccacagaacaga
cagacgaggatgttgcggaggaccagagtgggcggagagaaccgtgtctaa

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