Peromyscus leucopus (white-footed mouse): 114687957
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Entry
114687957 CDS
T07241
Symbol
Jak3
Name
(RefSeq) LOW QUALITY PROTEIN: tyrosine-protein kinase JAK3
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu04062
Chemokine signaling pathway
pleu04151
PI3K-Akt signaling pathway
pleu04217
Necroptosis
pleu04550
Signaling pathways regulating pluripotency of stem cells
pleu04630
JAK-STAT signaling pathway
pleu04658
Th1 and Th2 cell differentiation
pleu04659
Th17 cell differentiation
pleu05161
Hepatitis B
pleu05162
Measles
pleu05166
Human T-cell leukemia virus 1 infection
pleu05169
Epstein-Barr virus infection
pleu05200
Pathways in cancer
pleu05203
Viral carcinogenesis
pleu05223
Non-small cell lung cancer
pleu05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
114687957 (Jak3)
04151 PI3K-Akt signaling pathway
114687957 (Jak3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
114687957 (Jak3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
114687957 (Jak3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
114687957 (Jak3)
04659 Th17 cell differentiation
114687957 (Jak3)
04062 Chemokine signaling pathway
114687957 (Jak3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
114687957 (Jak3)
05203 Viral carcinogenesis
114687957 (Jak3)
09162 Cancer: specific types
05223 Non-small cell lung cancer
114687957 (Jak3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
114687957 (Jak3)
05161 Hepatitis B
114687957 (Jak3)
05162 Measles
114687957 (Jak3)
05169 Epstein-Barr virus infection
114687957 (Jak3)
09163 Immune disease
05340 Primary immunodeficiency
114687957 (Jak3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pleu01001
]
114687957 (Jak3)
Enzymes [BR:
pleu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
114687957 (Jak3)
Protein kinases [BR:
pleu01001
]
Non-receptor tyrosine kinases
JAK family [OT]
114687957 (Jak3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
SH2_1
FERM_F1
Jak1_Phl
ABC1
Kinase-like
pKID
Haspin_kinase
FERM_M
Motif
Other DBs
NCBI-GeneID:
114687957
NCBI-ProteinID:
XP_028718422
LinkDB
All DBs
Position
17:54144967..54159408
Genome browser
AA seq
1113 aa
AA seq
DB search
MVMAPPSEETPLIPQRSCSLSSSEAGSLHVLLPPRGSGPPQRLSFSFGDYLAEDLCVQAA
KACGILPVYHSLFALATEDLSCWFSPSHIFSVEDVDTQVLVYRLRFYFPGWFGLETCHRF
GLRKDLTSAILDLHVLEHLFAQHRSDLVSGRLPVGLSLKEQGECLSLAVLDLAQMAREQA
QRPSELLKTVSYKACLPPGLRDLIQGLSFVTRRRIRRTVLQALRRVVACQADRYSLMAKY
ILDLERLHPAAAAETFRXGLPGAQEGPGLLRVEGGSGVAWSPGDQELFQTFCDFPEIVDV
SIKQAPRVGPAGEQRLVTITRMDGHILEAEFAGLPEALSFVALVDGYFRLTCDSRHFFCK
EVAPPRLLEEVAELCHGPITLDFAVHKLKAAGSLPGSYILRRSPQDYDSFLLTACVQTPL
GPDYKGCLIRRDPXGRLLLAGLSQPHRSLRELLAACWRSGLQVDGAALNLTXCCAPRPKE
KSNLIVVRTSCTPAPAPGRAPSCCALTQLSFHTIPADSLEWHENLGHGSFTKIYRGRRRE
TVDGETHDTEVLLKVMDARHRNCMESFLEAASLMSQVSYPHLVLLHGVCMAGDSIMVQEF
VYLGAIDTYLRKRGPLVPAGWKLQVIKQLAYALSYLEDKGLPHGNVSARKVLLAREGADG
SPPFIKLSDPGVSPAVLSLEMLTDRIPWVAPECLQEGRALGLEADKWGFGATAWEVFSGA
PVHITSLEPAKVGRGGEVRFYEDAGSAGPKWTELAALIAQCMAYDPGRRPSFRAVLRDLN
ASSHTPLAHVTPDYELLSDPTPGSLSPREELYSGAQLHACQDPSIFEERHLKYISLLGKG
NFGSVELCRYDPLGDNTGPLVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSY
GPGRQSLRLVMEYLPSGCLRDFLQRHRARLHTGRLLLFAWQICKGMEYLGARRCVHRDLA
ARNILVESEAHVKIADFGLAKLLPLGKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVW
SFGVVLYELFTYSDKSCSPSAEFLRMMGPEREGPALCRLLELLAEGRRLPPPPSCPIEVQ
ELMQLCWAPSPQERPAFSALSPQLDALWRGNPG
NT seq
3342 nt
NT seq
+upstream
nt +downstream
nt
atggtcatggcgcctccaagtgaggagacacctctgatcccgcagcgctcatgcagcctc
tcatcctcggaggcgggatccctgcacgtcctcctccctccccggggatccgggcctccc
cagagactgtcattctcttttggggactacctggcagaggatctgtgtgtgcaggcagcc
aaggcctgtggcatcctgcctgtttatcactcgctcttcgctctggccaccgaggacttg
tcttgctggttctctccaagccacatcttctccgtggaggacgtggacacccaagtcttg
gtctacaggctccgcttctatttccctggctggtttggcctggagacatgtcaccgcttt
gggctgcgcaaagatctgaccagcgccatcctcgacttacacgttttagaacacctcttt
gcccagcaccgcagcgacctggtgagcgggcgcctccccgtgggcctcagcctgaaggag
cagggggagtgcctgagcctggccgtgctggacctggcccagatggcccgggagcaggcc
cagcggcccagcgaactgctcaagaccgtcagctacaaggcctgcctgccgcccggcctg
cgcgacctgatccaggggctgagcttcgtgacgcgcaggcgcatccgcaggaccgtgctc
caggcgctgcgccgcgtggtggcctgccaggccgaccgctactcgctcatggccaagtac
atcctggacctggagcggctgcacccggcggccgccgccgagaccttccgcngtgggctc
cccggtgcccaagaggggccggggctcctgcgcgtggagggcggcagcggcgtcgcctgg
agccccggggaccaagagctcttccagaccttctgtgactttcccgagatcgtggacgtc
agcatcaagcaggccccgcgcgtgggcccggccggggagcagcggctggtcaccatcacc
aggatggacggccacatcctggaagcggagttcgcggggctgcccgaggcgctgtccttc
gtggccctcgtcgacggctacttccgcctgacctgcgactccaggcatttcttctgcaag
gaggtggcgccgccaaggctgctggaggaagtggcagagctgtgccacgggcccatcacg
ctggactttgcggtccacaagctgaaggccgcgggctccctcccgggctcctacattctc
cgccgcagccctcaggactacgacagctttcttctcacggcctgcgtgcagacgccgctg
ggcccggactacaagggctgcctcatccgccgggacccgnncgggcgccttctcctggcc
gggctcagccagccgcaccggagcctgcgcgagctcctggccgcctgctggcgctccggg
ctgcaggtggacggtgccgccctgaacctcactncctgctgcgccccccggcccaaggaa
aagtccaatttgatcgtggtgagaacgagctgcacccctgccccggcccccggccgcgcc
ccgtcctgctgcgcgctgacgcagctgagcttccacacaatccctgcggacagcctggag
tggcacgagaacctgggccacggctccttcaccaagatctaccggggtcgccggcgcgag
accgtggacggggagacgcacgacacggaagtgctcctgaaggtcatggacgccaggcac
cggaactgcatggagtcctttctggaagccgccagcttgatgagccaagtgtcctaccca
cacctggtgctgctgcatggcgtctgcatggctggagacagcatcatggtgcaggagttt
gtctacctgggcgccatcgacacgtacctgcgcaagcgcgggcccctggtgccggccggc
tggaagctgcaggtgatcaagcagctggcctacgccctcagctacttggaggacaaaggc
ctccctcacggcaacgtctcggcgcggaaggtgctcctggcccgcgagggggctgacggg
agtccccccttcatcaagctgagcgaccccggtgtcagccccgcggtgctgagcctggag
atgctcaccgacaggatcccctgggtggcccccgagtgtctgcaggaaggccgggcgctc
ggcctggaggccgacaagtggggcttcggcgccacggcgtgggaggtgttcagcggggca
ccggtgcacatcacctcgctggagcccgccaaggtggggcggggcggggaagtgaggttc
tacgaggacgcgggcagtgccggccccaagtggacggagctggcggcgctcatcgcgcag
tgcatggcctacgacccgggccggcggccgtccttccgcgcggtgctcagggacctcaac
gcctcatcacacaccccacttgcacatgtgaccccagattatgagctcctctcggacccg
acgccgggcagcctgagtccccgagaggagctgtacagtggcgcccagctgcacgcctgc
caggaccccagcatcttcgaggagaggcacctgaagtacatctcgctgctgggcaagggc
aacttcggcagtgtggagctgtgccgctatgaccccctgggggacaatacaggacccctg
gtggcagtgaagcagctacagcacagcgggccagaccagcagagggacttccagcgcgag
attcagatcctcaaggcgctgcacagtgacttcatcgtcaagtaccggggagttagctac
gggccgggtcgccagagcctgcggctggtgatggagtacctgcccagcggctgcctgcgg
gacttcctgcagcgccaccgcgcgcgcctgcacaccggccgcctgctgctgttcgcctgg
cagatctgcaagggcatggagtacctgggcgcgcgccgctgcgtgcaccgcgacctggct
gcgcgaaacatcctggtggagagcgaggcgcatgtcaagatcgcggacttcggcctcgcc
aagctgctgccgctcgggaaggactactacgtggtccgcgagccgggccagagccccatc
ttctggtacgcccccgaatccctgtccgacaacatcttctcccgccagtcggacgtgtgg
agcttcggcgtggtgctgtacgagctcttcacctacagcgacaagagctgcagcccgtca
gccgagttcctgcgcatgatggggccggagcgtgaagggccagccctctgccgccttctg
gagctgctggccgagggccgccgcctcccgccacctccctcctgccccatcgaggttcag
gagctcatgcagctgtgctgggcgcccagcccgcaggagcggccggccttcagcgccctg
agcccacagctggacgcgctgtggcgtggaaacccggggtag
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