KEGG   Peromyscus leucopus (white-footed mouse): 114688199
Entry
114688199         CDS       T07241                                 
Name
(RefSeq) NADPH-dependent 3-keto-steroid reductase HSD3B3-like
  KO
K00070  3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
Organism
pleu  Peromyscus leucopus (white-footed mouse)
Pathway
pleu00140  Steroid hormone biosynthesis
pleu01100  Metabolic pathways
pleu04913  Ovarian steroidogenesis
pleu04925  Aldosterone synthesis and secretion
pleu04927  Cortisol synthesis and secretion
pleu04934  Cushing syndrome
Module
pleu_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
pleu_M00110  C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
pleu_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
pleu_M00977  C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:pleu00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    114688199
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    114688199
   04925 Aldosterone synthesis and secretion
    114688199
   04927 Cortisol synthesis and secretion
    114688199
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    114688199
Enzymes [BR:pleu01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.145  3beta-hydroxy-Delta5-steroid dehydrogenase
     114688199
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.3  Transposing C=C bonds
    5.3.3.1  steroid Delta-isomerase
     114688199
SSDB
Motif
Pfam: 3Beta_HSD Epimerase NAD_binding_4
Other DBs
NCBI-GeneID: 114688199
NCBI-ProteinID: XP_028718656
LinkDB
Position
6:complement(72999194..73002994)
AA seq 277 aa
MMNFPYSGTQLLLDACVEASVPVFIYSSSVAVAGPNSYKDIIQNGCEEDNHESTWSHPYP
YSKKMAEKAVLAANGCTLKDGGTLHTCALRLPFIYGEGSQHISYVVNRALKNNGTLDNFA
KFSVVNPVFVSNAAWAHILAARGLRDPKKSPNIQGQFYYISDDTPHQSYDDLYYALSKDW
GLRLDSSWSLPLPLLYWLAFLLETVSFLLRPIYNFRPPFNRYMVTVLNCVFTFSYKKAQR
DLGYEPPVSWEEARQKTSQWIGSLVEQHKGTLNTKTQ
NT seq 834 nt   +upstreamnt  +downstreamnt
atgatgaacttcccatactcaggtactcagctcctgttggatgcttgtgtggaagccagt
gtcccagtcttcatctacagcagctcagtggctgtggctggaccaaactcctacaaggac
atcatccagaatggctgcgaagaagataatcatgaaagcacatggtctcatccataccca
tacagcaaaaagatggctgagaaggcagtgctggcagccaatgggtgcaccctgaaagat
ggtggcactttgcatacttgtgccttaagactcccattcatctatggggaagggagccaa
cacatttcatatgtagtgaatagagcactcaagaataatggcacacttgacaattttgcc
aaattctctgtggtcaacccagtgtttgtgagtaatgcagcctgggcacacattctggca
gccaggggcctacgagaccccaagaagtcaccaaacatccaaggccagttctactacatc
tcagatgacacccctcaccaaagctatgatgatttatattatgccctgagcaaggactgg
ggcctccgccttgattccagttggagccttcctctgcccctgctctactggcttgccttc
ctgttggaaactgtgagcttcctgctgcgtccaatctacaacttccggcctccttttaat
cgctatatggtcacagtgttaaattgtgtgttcaccttctcctacaagaaagctcagcga
gatctgggctatgagccacctgtcagctgggaggaggccagacaaaaaacttctcagtgg
atcgggtcactagtggagcagcacaaggggacactgaacacaaagactcagtga

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