Peromyscus leucopus (white-footed mouse): 114689662
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Entry
114689662 CDS
T07241
Symbol
Ret
Name
(RefSeq) proto-oncogene tyrosine-protein kinase receptor Ret
KO
K05126
proto-oncogene tyrosine-protein kinase Ret [EC:
2.7.10.1
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu04010
MAPK signaling pathway
pleu04020
Calcium signaling pathway
pleu04151
PI3K-Akt signaling pathway
pleu05200
Pathways in cancer
pleu05216
Thyroid cancer
pleu05223
Non-small cell lung cancer
pleu05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
114689662 (Ret)
04020 Calcium signaling pathway
114689662 (Ret)
04151 PI3K-Akt signaling pathway
114689662 (Ret)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
114689662 (Ret)
05230 Central carbon metabolism in cancer
114689662 (Ret)
09162 Cancer: specific types
05216 Thyroid cancer
114689662 (Ret)
05223 Non-small cell lung cancer
114689662 (Ret)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pleu01001
]
114689662 (Ret)
Enzymes [BR:
pleu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
114689662 (Ret)
Protein kinases [BR:
pleu01001
]
Receptor tyrosine kinases (RTK)
RET family
114689662 (Ret)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
RET_CLD4
RET_CLD3
RET_CLD1
Pkinase
RET_CRD
Cadherin
RIO1
Pkinase_fungal
Haspin_kinase
ABC1
Motif
Other DBs
NCBI-GeneID:
114689662
NCBI-ProteinID:
XP_028719901
LinkDB
All DBs
Position
3:152595800..152639920
Genome browser
AA seq
1115 aa
AA seq
DB search
MAKATSGAPGLGLKLFLLLPLLGEAPLGLYFSKDTYWERLYVDQPPGTPLLYVHALRDAP
EEVPSFRLGQHLSSAFRTRLHENDWIRIHEDTGLLYLNQSLDHSSWEQLSIRNGGFPLLT
IFLQVFLGSSTQREGECHWPGCARVYFSFINDSFPACSSLKPQDLCVRETGLSFRIRENR
PPGTFYQLHLLPVQFLCPNISVTYRLLEEESLPFRCNPDTLEVSTRWALDRELQEKYVLE
AECSVGTGASEEKVTVSLPVTVYDEDDSAPTFSGGVDTASAVVEFKRKEGTVVATLHVFD
ADVVPASGELVRRYTSTLLSGDSWAQQNFRVEHSPNETLAQANNNSVRATMHDYKLVLNR
SLPISESRVLQLVVLVNDSDFQGPGTGVLFLHFNVSVLPVTLNLPSAYSFPVNRGAHLYA
QIGKVCVENCQEFSGISVQYKLQPSSTNCSVLGVVTSAEDTSGTLFVNDTEALQRPECAE
HQYMVVATDKQTRQQAQASLLITVEGTYVAEEEDCPKSCAGNKRRPDCEECGGLGSPTGR
CEWRQGDGKGITRNFSTCSPSIRTCPDGHCDAVESRDIDNICPQDCLRGSIVGGHEPGER
RGIKAGYGTCYCLPDEKKCFCEPEDSQGPLCDELCRTVITAAVLFSFIISVLLSTFCIHR
YHKHAHKPPIASAEMTFCRPAQGFPISYSSSGTRRPSLDSMENQVSVDSFKIPEDPKWEF
PRKNLVLGKTLGEGEFGKVVKATAFRLKGRAGYTTVAVKMLKENASQSELRDLLSEFNLL
KQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRDSRKIGPGYVGSGGSRNSSSLD
HPDERVLTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDV
YEEDSYVKKSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPER
LFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKSRDYLDLA
ASTPSDSLLYDDGLSEEETPLVDCNSAPLPRSLPSTWIENKLYGMSDPNWPGESPVPLTR
ADGTSTGCPRYANDSVYANWMVSPSAAKLMDTLDS
NT seq
3348 nt
NT seq
+upstream
nt +downstream
nt
atggcgaaagcgacgtccggcgccccggggctggggctgaagctgtttttgctgctgccg
ctgctgggcgaagccccgctgggcctctacttctcaaaggatacttactgggagaggctg
tatgtggaccagccacctggcacacccctgctctatgtccatgccctccgggatgcccct
gaagaagtccccagcttccgcctgggccagcatctctctagcgccttccgcacacggctg
catgagaatgattggatccgcatccatgaggacactggccttctctacctcaaccagagc
ctggaccacagttcctgggaacagctcagcattcgcaacggtggcttccccttgctcacc
atcttcctccaggtcttcctggggtcctcaacccagcgggagggcgaatgtcattggcca
ggctgtgcccgggtgtacttctccttcatcaatgactccttcccagcctgtagctccctc
aaacctcaggacctctgtgtccgggagacgggcctgtccttccgcatcagggagaacagg
cccccgggcaccttctaccaattacacctgttgcctgtgcagttcctgtgccccaacatc
agtgtgacctacaggctcctggaagaggagagtctgcccttccgttgcaacccagacacc
ttggaggtgagcacccgctgggccctggaccgggagcttcaggagaagtatgtgctggag
gccgagtgcagcgtgggcaccggtgccagcgaagagaaggtgaccgtgtccctcccggtg
accgtgtacgatgaggacgactcggcacccaccttctccggaggtgtggacactgccagt
gctgtggtggagtttaagcggaaggagggcactgtggtggccacgctgcatgtgtttgat
gcagatgtggtgccagcatctggggagctggtgagacggtacacaagcacactactctca
ggggactcctgggcccagcagaacttccgggtggagcactcacccaacgagaccttggcc
caggccaacaacaactccgtgcgggcaaccatgcacgattacaagctggttctcaaccgg
agcctccccatctcagagagccgagtcctgcagctggtggtcctggtcaatgactcagac
ttccaggggcctgggacaggtgtcctcttcctccacttcaacgtgtctgtgctgcctgtc
accctgaacctacccagtgcctactcgttcccagtgaacagaggagctcacctttatgcc
cagattgggaaagtctgtgtggaaaactgccaggagttcagcggcatctccgtccagtac
aagctacagccctccagcaccaactgcagtgttctaggtgtggtcacctcggctgaggac
acctcggggaccctcttcgtaaatgacacagaggccctgcagcgacctgaatgtgccgag
catcagtacatggtggtagccactgacaagcagacccgccagcaggcccaggcttcactg
ctcatcacagtggaggggacatacgttgctgaagaagaggactgccccaaatcctgtgca
ggcaacaagagacggcctgactgtgaggagtgtggtggcctaggctctcccacgggcaga
tgcgagtggcgtcagggagacggcaaaggaatcaccaggaacttctctacctgctccccc
agcatcaggacctgccccgatggccactgtgatgctgtggagagccgggatatcgacaac
atttgcccccaggactgtctccgtggcagcattgttggaggacacgagcccggggagcgc
cgggggattaaagctggctatggtacctgctactgcttacctgacgagaagaagtgcttc
tgcgagccagaggacagccagggtccgctgtgtgacgagctgtgccgcaccgtgatcaca
gctgccgtcctcttctccttcatcatctcggtcctgctgtccacgttctgcatccaccgc
taccacaagcacgcgcacaagccgcccattgcttccgcggaaatgaccttctgccggcca
gcccagggcttcccaatcagctattcctcctcggggacccgccggccctccctggattcc
atggagaaccaggtgtctgtggactctttcaagatcccggaggatccaaagtgggaattt
cctcggaagaacttggttcttggcaaaaccctaggagaaggagagtttggaaaggtggtc
aaggcgacagccttccgtctaaaaggccgagcaggatacaccacagtggccgtgaaaatg
ctgaaagaaaacgcctcccagagtgagctccgagacctgctgtctgagttcaacctcttg
aagcaggtcaaccatccacatgtcatcaagctgtatggagcctgcagccaggacgggcca
cttcttctcattgtggagtatgccaagtatggctccctgcggggattcctccgtgacagc
cgcaagattgggcctggctacgtgggcagtggaggcagccgcaattccagctccctagac
cacccggatgaacgggtactgaccatgggcgacctcatctcctttgcctggcagatctca
aggggtatgcagtacttggctgagatgaagctcgtacatcgggacttagctgccaggaac
atcttggtggctgaaggacggaagatgaagatttctgattttgggctgtcccgagatgtt
tacgaagaagattcctatgtgaagaaaagcaagggccggattcctgtcaaatggatggca
atcgagtccctttttgatcatatctataccacccaaagtgatgtgtggtcctttggggta
ctcctatgggagattgtgaccctggggggcaacccctaccctggaattcctcctgaacga
ctcttcaaccttctgaagacgggccacaggatggagaggccggacaactgcagtgaggaa
atgtaccgcctgatgctgcagtgctggaaacaggagccagacaagaggccagtatttgct
gacatcagcaaggatctggagaagatgatggtcaagagcagagactacttggacctggca
gcctccaccccgtctgactcactgctttacgatgacggcctctcggaagaggagacgccc
ctggtggactgtaacagcgctcccctcccgcgctccctcccttccacatggattgaaaac
aaactctatggcatgtcagacccgaactggcctggagagagtcctgtaccactcacgaga
gccgatggcactagcactgggtgcccgagatatgcaaatgatagtgtatatgctaactgg
atggtttcaccctcagcggcaaaattaatggacacacttgatagttaa
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