Peromyscus leucopus (white-footed mouse): 114693220
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Entry
114693220 CDS
T07241
Symbol
Alox12
Name
(RefSeq) polyunsaturated fatty acid lipoxygenase ALOX12
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu00590
Arachidonic acid metabolism
pleu01100
Metabolic pathways
pleu01523
Antifolate resistance
pleu04726
Serotonergic synapse
pleu04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
114693220 (Alox12)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
114693220 (Alox12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
114693220 (Alox12)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
114693220 (Alox12)
Enzymes [BR:
pleu01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
114693220 (Alox12)
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Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
114693220
NCBI-ProteinID:
XP_028725370
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Position
8b:complement(53207961..53220494)
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AA seq
663 aa
AA seq
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MGRYRVRVVTGAWLFSGSLNRVGLWLVGAHREAKLELQLRPARGKEEEFDFDVAEDLGPL
QFVKLHKQHSVVDDAWFCDIIAIQAPGTSAEAVFPCYRWVQGEGVLSLPEGTARLAGDNA
LDVFQQHREKELKERQQIYRWATWKEGLPQTIAADCKDDLPLNMRFHEEKRLDFEWTLKA
GVLEMGLKRVYTLLRSWNRLEDFDQIFWGQKSALAEKVHRCWQDDELFGYQFLNGANPML
LRRSTSLPSRLVLPSGTEELQAQLEKELQNGSLFEVDFILLDGIPANVIGGEQQYLAAPL
VLLRMDPRGKLLPMAIQIQPPSSSSPAPTLFLPSDPPLAWLLAKIWVRSSDFQLQELQFH
LLNTHLVAEVIAVATMRCLPGLHPIFKLLVPHIRYTMEINTRSRTQLISDGGIFDQVVST
GGGGHVQLLNRAMAQLTYCSLCPPDDLADRGLLRLPSALYAQDALQLWEVTARYVEGMVH
LFYQSDDIVRGDPELQAWCREITEVGLCHAQDRGFPVSFQTRAQLGHFLTMCIFTCTAQH
AAINQGQLDWFGWVPNAPCTMRMPPPTNKEGVTMETVMGSLPDVHKSCLQMTITWHLGRL
QPDMVPLGQHKEKYFSDPRTKTVLSRFQADLGNLEREIIARNEQLDLPYEYLKPSRIENS
ITI
NT seq
1992 nt
NT seq
+upstream
nt +downstream
nt
atgggccgctaccgcgtccgtgtggtcactggggcctggctcttctcgggatccctcaac
cgagtggggctgtggctggttggggcgcatcgggaggcgaaactggagctgcagctgagg
cccgcgaggggcaaggaggaggagtttgacttcgatgttgccgaggacttggggccactg
cagtttgtgaaactccacaaacagcactcagtggtggacgacgcctggttctgcgacatc
atcgcgattcaggcgcccggaacaagcgccgaggcagtgttcccctgctaccgctgggtg
cagggagagggagtactaagcctgcccgaggggacagcccgcctggcaggagacaatgcc
ttggatgtcttccagcagcatcgagagaaggaactgaaggagaggcagcagatctaccgc
tgggccacctggaaggaaggcttacctcagacaatagcggcagactgtaaggatgacctg
cctctcaatatgagattccacgaggagaagaggctggactttgaatggacgctgaaggcg
ggggttctggaaatgggtctcaaacgtgtttacaccctcctgagaagctggaaccgtctg
gaagactttgatcagatcttctggggccagaagagtgccttggctgagaaggttcaccgg
tgctggcaggatgatgagctttttggctaccagttcctcaatggtgccaaccccatgctg
ttgagacgctccacctctctgccctccaggctggtactgccctctgggacagaggagctc
caagcccagttggagaaagaactccagaatggttccctgtttgaagttgactttattctg
ctggatgggattccagccaacgtgatcggaggagagcagcagtacctggccgcccctctt
gtcctgctgaggatggacccccgtgggaagctgctacccatggctatccagattcagcct
cccagttccagctccccagctccaacattgttcctgccctcagatcctcctcttgcctgg
ctcttggctaagatctgggtccgaagttcagatttccagctgcaggagctccagttccat
ttgctgaacactcatctggtggctgaggtcatcgctgttgccaccatgaggtgcctccca
ggactgcaccctatcttcaagctcctagttccccacatccgttacactatggaaatcaac
acacgaagccggacccagctcatctcagatggcggaatatttgatcaggtagtgagcaca
ggaggagggggccatgttcagttgctcaatcgggcaatggctcagctgacttactgctcc
ctctgtcctcctgacgacctggctgaccgaggcctgctgagactcccgagtgctctctat
gctcaggatgctttgcagctctgggaagtcactgccaggtacgtggaagggatggtccac
ctcttctaccagagtgacgacattgtgaggggagacccagagctgcaggcctggtgtcgg
gagatcactgaggtgggactgtgccatgcccaggacagaggtttccctgtctccttccag
acccgggctcagctgggacatttccttaccatgtgtatcttcacgtgcactgcccagcat
gctgccatcaatcagggccagctggactggttcggttgggtacctaatgctccatgcaca
atgaggatgcccccacccaccaacaaggaaggcgttactatggagacggtgatgggctca
ctacccgacgttcacaagtcctgtcttcaaatgaccatcacatggcatctgggtcgcctc
cagccagacatggtacccctaggacaacacaaagaaaaatatttctcagatcccaggacc
aaaactgtgctcagccgatttcaagcagatttggggaatttggaaagagagattatagcc
cggaatgagcaactggacctgccctatgaatacctcaagcccagccgcatagagaacagt
atcactatctga
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