Peromyscus leucopus (white-footed mouse): 114700348
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Entry
114700348 CDS
T07241
Symbol
Bace2
Name
(RefSeq) beta-secretase 2 isoform X1
KO
K07747
beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:
3.4.23.45
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
114700348 (Bace2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
pleu01002
]
114700348 (Bace2)
Enzymes [BR:
pleu01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.45 memapsin 1
114700348 (Bace2)
Peptidases and inhibitors [BR:
pleu01002
]
Aspartic peptidases
Family A1: pepsin family
114700348 (Bace2)
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Motif
Pfam:
Asp
TAXi_C
TAXi_N
Motif
Other DBs
NCBI-GeneID:
114700348
NCBI-ProteinID:
XP_028735755
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Position
12:complement(716027..797726)
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AA seq
514 aa
AA seq
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MGALLRALLLPLLAQWLLRAAPALAPAPFTLPLQVAAATSRGSSAVPGLGTPEMPRADGL
ALALEPAGAAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAGAPHS
YIDSYFDSERSSTYHPKGFDVTVKYTQGSWTGFVGEDIVTIPKGFNSSFLVNIATILESE
NFFLPGIKWNGILGLAYAALAKPSSSLETFFDSLVAQAKIPDIFSMQMCGAGLPVAGSGT
NGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDS
GTTLLRLPQKVFDAVVEAVARTSLIPEFSDGFWTGAQLACWTNSETPWAYFPKISIYLRD
ENSSRSFRITILPQLYIQPMMGAGLNYECYRFGISSSTNALVIGATVMEGFYVVFDRARK
RVGFAASPCAEIAGTTVSEISGPFSTGDIASSCVPAPALNEPILWIVSYALMSVCGVILL
VLILLLLLPVHCRHAPRDPEVVNDESSLVRHRWK
NT seq
1545 nt
NT seq
+upstream
nt +downstream
nt
atgggcgcgctgctccgagcgctcctgctcccgctgttggcgcagtggctcttgcgcgca
gcccccgcgctggccccagcgcccttcacgctacccctccaggtggccgcagccacgagc
cgcggatcctcggccgttcccgggctcgggacccctgagatgccccgtgcagatggcctg
gcgctagcgctggagcccgccggggctgccgccaacttcttggctatggtggacaacctg
cagggggactctggccgcggctactacctggagatgctgatcgggaccccgccgcagaag
ctacagattcttgtggacactggaagcagtaacttcgctgtggcaggtgccccacattcc
tacatagactcctactttgactcagagagatccagcacatatcaccccaagggctttgat
gtcactgtgaagtacacacagggaagctggactggctttgttggtgaggacattgttacc
atcccaaaaggcttcaacagctctttcctggtcaacattgccactattttggagtctgag
aatttctttttgcctgggattaaatggaatggaattctcggacttgcttatgctgccctg
gccaagccatcaagctctctggagaccttctttgattccctggtggcccaagcaaagatt
ccagacattttctccatgcagatgtgtggggctggattgccagtagccggatctggtacc
aacggaggtagtcttgtcctaggtgggatcgaaccaagtttgtataaaggagacatctgg
tataccccaattaaagaggagtggtactatcagatagagatcctgaaattggaaattgga
ggccagagcctcaacctggactgcagagagtataatgcagacaaggccattgtggacagc
ggcaccacgctcctgcgcctgccccagaaggtgttcgatgcggtggtggaagctgtggca
cgcacgtctctgattccagagttttctgatggcttctggacaggggcccagctggcatgc
tggacaaattctgaaacgccgtgggcgtatttccctaagatctctatctacctgagagat
gagaactccagtcgctccttccgaatcaccattctgccacagctctacattcagcccatg
atgggagctggtctcaattatgagtgttaccgttttggtatctcctcttccacaaacgca
ctggtgattggtgccaccgtgatggagggcttctacgtggtctttgacagagctcggaag
agggtgggctttgcagcgagtccctgtgcagagattgcaggtaccacagtgtctgagatt
tccgggcccttttccacgggagacatagccagcagctgtgtcccagcaccggctctgaat
gagcccatcttgtggattgtgtcctatgccctgatgagcgtgtgtggagtcatcctcctg
gttctgatcctcctcctgctgctcccagtgcactgccgacatgctccccgtgaccctgag
gtcgtcaatgatgagtcctcactggtcagacatcgatggaaatga
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